Imperial College London
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ProfessorEricKerrigan

Faculty of Engineering, Department of Electrical and Electronic Engineering

Professor of Control and Optimization
 
 
 
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Contact

 

+44 (0)20 7594 6343e.kerrigan Website

 
 
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Assistant

 

Mrs Raluca Reynolds +44 (0)20 7594 6281

 
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Location

 

1114Electrical EngineeringSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Solis-Lemus:2020:10.1098/rsos.200585,
author = {Solis-Lemus, JA and Costar, E and Doorly, D and Kerrigan, EC and Kennedy, CH and Tait, F and Niederer, S and Vincent, PE and Williams, SE},
doi = {10.1098/rsos.200585},
journal = {Royal Society Open Science},
pages = {1--12},
title = {A simulated single ventilator/dual patient ventilation strategy for acute respiratory distress syndrome during the COVID-19 pandemic},
url = {http://dx.doi.org/10.1098/rsos.200585},
volume = {7},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The potential for acute shortages of ventilators at the peak of the COVID-19 pandemic has raised the possibility of needing to support two patients from a single ventilator. To provide a system for understanding and prototyping designs, we have developed a mathematical model of two patients supported by a mechanical ventilator. We propose a standard set-up where we simulate the introduction of T-splitters to supply air to two patients and a modified set-up where we introduce a variable resistance in each inhalation pathway and one-way valves in each exhalation pathway. Using the standard set-up, we demonstrate that ventilating two patients with mismatched lung compliances from a single ventilator will lead to clinically significant reductions in tidal volume in the patient with the lowest respiratory compliance. Using the modified set-up, we demonstrate that it could be possible to achieve the same tidal volumes in two patients with mismatched lung compliances, and we show that the tidal volume of one patient can be manipulated independently of the other. The results indicate that, with appropriate modifications, two patients could be supported from a single ventilator with independent control of tidal volumes.
AU  - Solis-Lemus,JA
AU  - Costar,E
AU  - Doorly,D
AU  - Kerrigan,EC
AU  - Kennedy,CH
AU  - Tait,F
AU  - Niederer,S
AU  - Vincent,PE
AU  - Williams,SE
DO  - 10.1098/rsos.200585
EP  - 12
PY  - 2020///
SN  - 2054-5703
SP  - 1
TI  - A simulated single ventilator/dual patient ventilation strategy for acute respiratory distress syndrome during the COVID-19 pandemic
T2  - Royal Society Open Science
UR  - http://dx.doi.org/10.1098/rsos.200585
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000565132700001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://royalsocietypublishing.org/doi/10.1098/rsos.200585
UR  - http://hdl.handle.net/10044/1/104347
VL  - 7
ER  -
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