Imperial College London
Alternate

ProfessorElioRiboli

Faculty of Medicine, School of Public Health

Chair in Cancer Epidemiology and Prevention
 
 
 
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Contact

 

e.riboli Website CV

 
 
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Assistant

 

Ms Julieta Dourado +44 (0)20 7594 3426

 
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Location

 

152Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Aune:2018:10.1007/s10654-017-0351-y,
author = {Aune, D and Schlesinger, S and Norat, T and Riboli, E},
doi = {10.1007/s10654-017-0351-y},
journal = {European Journal of Epidemiology},
pages = {509--521},
title = {Tobacco smoking and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies},
url = {http://dx.doi.org/10.1007/s10654-017-0351-y},
volume = {33},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Smoking is an established risk factor for cardiovascular disease including coronary heart disease and stroke, however, data regarding smoking and sudden cardiac death have not been summarized in a meta-analysis previously. We therefore conducted a systematic review and meta-analysis to clarify this association. We searched the PubMed and Embase databases for studies of smoking and sudden cardiac death up to July 20th 2017. Prospective studies were included if they reported adjusted relative risk (RR) estimates and 95% confidence intervals (CIs) for smoking and sudden cardiac death. Summary RRs were estimated by use of a random effects model. Twelve prospective studies were included. The summary RR was 3.06 (95% CI 2.46-3.82, I2 = 41%, pheterogeneity = 0.12, n = 7) for current smokers and 1.38 (95% CI 1.20-1.60, I2 = 0%, pheterogeneity = 0.55, n = 7) for former smokers compared to never smokers. For four studies using non-current (never + former) smokers as the reference category the summary RR among current smokers was 2.08 (95% CI 1.70-2.53, I2 = 18%, pheterogeneity = 0.30). The results persisted in most of the subgroup analyses. There was no evidence of publication bias. These results confirm that smoking increases the risk of sudden cardiac death. Any further studies should investigate in more detail the effects of duration of smoking, number of cigarettes per day, pack-years, and time since quitting smoking and sudden cardiac death.
AU  - Aune,D
AU  - Schlesinger,S
AU  - Norat,T
AU  - Riboli,E
DO  - 10.1007/s10654-017-0351-y
EP  - 521
PY  - 2018///
SN  - 0393-2990
SP  - 509
TI  - Tobacco smoking and the risk of sudden cardiac death: a systematic review and meta-analysis of prospective studies
T2  - European Journal of Epidemiology
UR  - http://dx.doi.org/10.1007/s10654-017-0351-y
UR  - http://hdl.handle.net/10044/1/57038
VL  - 33
ER  -
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