Imperial College London
Alternate

ProfessorEstherRodriguez Villegas

Faculty of Engineering, Department of Electrical and Electronic Engineering

Professor in Low Power Electronics
 
 
 
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Contact

 

+44 (0)20 7594 6193e.rodriguez

 
 
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Location

 

914Electrical EngineeringSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Jiang:2017:10.1038/s41598-017-08078-8,
author = {Jiang, Z and Huxter, JR and Bowyer, S and Blockeel, AJ and Butler, J and imtiaz and Wafford, KA and Phillips, KG and Tricklebank, MD and Marston, HM and Rodriguez, E},
doi = {10.1038/s41598-017-08078-8},
journal = {Scientific Reports},
title = {TaiNi: maximizing research output whilst improving animals' welfare in neurophysiology experiments},
url = {http://dx.doi.org/10.1038/s41598-017-08078-8},
volume = {7},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Understanding brain function at the cell and circuit level requires representation of neuronal activity through multiple recording sites and at high sampling rates. Traditional tethered recording systems restrict movement and limit the environments suitable for testing, while existing wireless technology is still too heavy for extended recording in mice. Here we tested TaiNi, a novel ultra-lightweight (<2 g) low power wireless system allowing 72-hours of recording from 16 channels sampled at ~19.5 KHz (9.7 KHz bandwidth). We captured local field potentials and action-potentials while mice engaged in unrestricted behaviour in a variety of environments and while performing tasks. Data was synchronized to behaviour with sub-second precision. Comparisons with a state-of-the-art wireless system demonstrated a significant improvement in behaviour owing to reduced weight. Parallel recordings with a tethered system revealed similar spike detection and clustering. TaiNi represents a significant advance in both animal welfare in electrophysiological experiments, and the scope for continuously recording large amounts of data from small animals.
AU  - Jiang,Z
AU  - Huxter,JR
AU  - Bowyer,S
AU  - Blockeel,AJ
AU  - Butler,J
AU  - imtiaz
AU  - Wafford,KA
AU  - Phillips,KG
AU  - Tricklebank,MD
AU  - Marston,HM
AU  - Rodriguez,E
DO  - 10.1038/s41598-017-08078-8
PY  - 2017///
SN  - 2045-2322
TI  - TaiNi: maximizing research output whilst improving animals' welfare in neurophysiology experiments
T2  - Scientific Reports
UR  - http://dx.doi.org/10.1038/s41598-017-08078-8
UR  - http://hdl.handle.net/10044/1/49905
VL  - 7
ER  -
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