Imperial College London
Portrait Picture

Prof Ed Tate

Faculty of Natural Sciences, Department of Chemistry

GSK Chair in Chemical Biology
 
 
 
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Contact

 

+44 (0)20 7594 3752e.tate Website CV

 
 
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Assistant

 

Ms Agnes Lee +44 (0)20 7594 9852

 
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Location

 

301BMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Beard:2018:10.1039/c8cc01400k,
author = {Beard, R and Singh, N and Grundschober, C and Gee, AD and Tate, EW},
doi = {10.1039/c8cc01400k},
journal = {Chemical Communications},
pages = {8120--8123},
title = {High-yielding 18F radiosynthesis of a novel oxytocin receptor tracer, a probe for nose-to-brain oxytocin uptake in vivo},
url = {http://dx.doi.org/10.1039/c8cc01400k},
volume = {54},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - A novel Al18F labelled peptide tracer for PET imaging of oxytocin receptor has been accessed through a high radiochemical yield approach. This tracer showed comparable affinity and higher selectivity and stability compared to oxytocin, and was used to demonstrate direct nose-to-brain uptake following intranasal administration, a common yet controversial delivery route for oxytocin-based therapeutics.
AU  - Beard,R
AU  - Singh,N
AU  - Grundschober,C
AU  - Gee,AD
AU  - Tate,EW
DO  - 10.1039/c8cc01400k
EP  - 8123
PY  - 2018///
SN  - 1359-7345
SP  - 8120
TI  - High-yielding 18F radiosynthesis of a novel oxytocin receptor tracer, a probe for nose-to-brain oxytocin uptake in vivo
T2  - Chemical Communications
UR  - http://dx.doi.org/10.1039/c8cc01400k
UR  - http://hdl.handle.net/10044/1/60028
VL  - 54
ER  -
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