Imperial College London

Dr Fu Siong Ng

Faculty of MedicineNational Heart & Lung Institute

Clinical Senior Lecturer in Cardiac Electrophysiology
 
 
 
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Contact

 

+44 (0)20 7594 3614f.ng Website

 
 
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Location

 

ICTEM buildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Ng:2014:europace/euu237.9,
author = {Ng, FS and Debney, MT and Protti, A and Lyon, AR and Shah, AM and Peters, NS},
doi = {europace/euu237.9},
journal = {Europace},
title = {15Early pharmacological enhancement of gap junction coupling with rotigaptide reduces arrhythmia vulnerability and modulates structural remodelling in reperfused myocardial infarction.},
url = {http://dx.doi.org/10.1093/europace/euu237.9},
volume = {16 Suppl 3},
year = {2014}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Survivors of myocardial infarction (MI) are at increased risk of late ventricular arrhythmias and sudden cardiac death with infarct size and scar heterogeneity as key determinants of arrhythmic risk. Current preventative strategies are limited to few, select antiarrhythmic drugs or an implantable cardioverter-defibrillator. Cardiac gap junctions (GJ) have a key role in allowing the passage of small molecules between cells and may mediate the spread of acute myocardial infarction. We hypothesised that enhancing GJ coupling in the acute phase of MI may beneficially modify the extent and pattern of necrosis and infarction acutely, thus affording a protective effect against late arrhythmogenesis.
AU - Ng,FS
AU - Debney,MT
AU - Protti,A
AU - Lyon,AR
AU - Shah,AM
AU - Peters,NS
DO - europace/euu237.9
PY - 2014///
TI - 15Early pharmacological enhancement of gap junction coupling with rotigaptide reduces arrhythmia vulnerability and modulates structural remodelling in reperfused myocardial infarction.
T2 - Europace
UR - http://dx.doi.org/10.1093/europace/euu237.9
UR - http://www.ncbi.nlm.nih.gov/pubmed/25298502
VL - 16 Suppl 3
ER -