Imperial College London

DrGeoffBaldwin

Faculty of Natural SciencesDepartment of Life Sciences

Reader in Biochemistry
 
 
 
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Contact

 

+44 (0)20 7594 5288g.baldwin

 
 
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Location

 

508Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@book{Baldwin:2012:10.1142/P837,
author = {Baldwin, G and Bayer, T and Dickinson, R and Ellis, T and Freemont, PS and Kitney, RI and Polizzi, K and Stan, GB},
doi = {10.1142/P837},
title = {Synthetic Biology - A Primer},
url = {http://dx.doi.org/10.1142/P837},
year = {2012}
}

RIS format (EndNote, RefMan)

TY  - BOOK
AB - © 2012 by Imperial College Press. All rights reserved. Synthetic Biology — A Primer gives a broad overview of the emerging field of synthetic biology and the foundational concepts on which it is built. It will be of interest to final year undergraduates, postgraduates and established researchers who are interested in learning about this exciting new field. The book introduces readers to fundamental concepts in molecular biology and engineering and then explores the two major themes for synthetic biology, namely ‘bottom-up’ and ‘top-down’ engineering approaches. ‘Top-down’ engineering utilises a conceptual framework of engineering and systematic design to build new biological systems by integrating robustly characterised biological parts into an existing system through the use of extensive mathematical modelling. The ‘bottom-up’ approach involves the design and building of synthetic protocells using basic chemical and biochemical building blocks from scratch. Exemplars of cutting-edge applications designed using synthetic biology principles are presented, including the production of novel biofuels from renewable feedstocks, microbial synthesis of pharmaceuticals and fine chemicals, and the design and implementation of biosensors to detect infections and environmental waste. The book also uses the Internationally Genetically Engineered Machine (iGEM) competition to illustrate the power of synthetic biology as an innovative research and training science. Finally, the primer includes a chapter on the ethical, legal and societal issues surrounding synthetic biology, illustrating the integration of social sciences in synthetic biology research.
AU - Baldwin,G
AU - Bayer,T
AU - Dickinson,R
AU - Ellis,T
AU - Freemont,PS
AU - Kitney,RI
AU - Polizzi,K
AU - Stan,GB
DO - 10.1142/P837
PY - 2012///
SN - 9781848168626
TI - Synthetic Biology - A Primer
UR - http://dx.doi.org/10.1142/P837
ER -