Imperial College London
Alternate

DrGabrielBirgand

Faculty of Medicine, Department of Infectious Disease

Honorary Research Fellow
 
 
 
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Contact

 

+44 (0)20 3313 2732g.birgand Website CV

 
 
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Location

 

Commonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Charani:2017:10.1016/j.ijid.2017.04.020,
author = {Charani, E and Ahmad, R and Tarrant, C and Birgand, G and Leather, A and Mendelson, M and Moonesinghe, SR and Sevdalis, N and Singh, S and Holmes, A},
doi = {10.1016/j.ijid.2017.04.020},
journal = {International Journal of Infectious Diseases},
pages = {29--34},
title = {Opportunities for system level improvement in antibiotic use across the surgical pathway},
url = {http://dx.doi.org/10.1016/j.ijid.2017.04.020},
volume = {60},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Optimizing antibiotic prescribing across the surgical pathway (before, during, and after surgery) is a key aspect of tackling important drivers of antimicrobial resistance and simultaneously decreasing the burden of infection at the global level. In the UK alone, 10 million patients undergo surgery every year, which is equivalent to 60% of the annual hospital admissions having a surgical intervention. The overwhelming majority of surgical procedures require effectively limited delivery of antibiotic prophylaxis to prevent infections. Evidence from around the world indicates that antibiotics for surgical prophylaxis are administered ineffectively, or are extended for an inappropriate duration of time postoperatively. Ineffective antibiotic prophylaxis can contribute to the development of surgical site infections (SSIs), which represent a significant global burden of disease. The World Health Organization estimates SSI rates of up to 50% in postoperative surgical patients (depending on the type of surgery), with a particular problem in low- and middle-income countries, where SSIs are the most frequently reported healthcare-associated infections. Across European hospitals, SSIs alone comprise 19.6% of all healthcare-acquired infections. Much of the scientific research in infection management in surgery is related to infection prevention and control in the operating room, surgical prophylaxis, and the management of SSIs, with many studies focusing on infection within the 30-day postoperative period. However it is important to note that SSIs represent only one of the many types of infection that can occur postoperatively. This article provides an overview of the surgical pathway and considers infection management and antibiotic prescribing at each step of the pathway. The aim was to identify the implications for research and opportunities for system improvement.
AU  - Charani,E
AU  - Ahmad,R
AU  - Tarrant,C
AU  - Birgand,G
AU  - Leather,A
AU  - Mendelson,M
AU  - Moonesinghe,SR
AU  - Sevdalis,N
AU  - Singh,S
AU  - Holmes,A
DO  - 10.1016/j.ijid.2017.04.020
EP  - 34
PY  - 2017///
SN  - 1201-9712
SP  - 29
TI  - Opportunities for system level improvement in antibiotic use across the surgical pathway
T2  - International Journal of Infectious Diseases
UR  - http://dx.doi.org/10.1016/j.ijid.2017.04.020
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000405489800006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/50657
VL  - 60
ER  -
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