Imperial College London


Faculty of MedicineDepartment of Medicine

Reader in Infectious Diseases



+44 (0)20 7594 3903g.cooke




Infectious Diseases SectionWinston Churchill WingSt Mary's Campus





Graham Cooke is a clinician scientist based within the Division of Infectious Diseases at the Wright-Fleming Institute. He trained in General Medicine and Infectious Diseases, working in Oxford, London and South Africa. Prior to taking up his current position,  he was based at the Africa Health Research Institute  in KwaZulu-Natal.

His current work is focussed on stratified/precision medicine in infection, particularly HIV and viral hepatitis.


Funding: Wellcome Trust, NIHR, MRC, Médecins sans Frontières, BRC Imperial College


Follow on twitter: @grahamscooke

Selected Publications

Journal Articles

Ansari MA, Pedergnana V, Ip CLC, et al., 2017, Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus, Nature Genetics, Vol:49, ISSN:1061-4036, Pages:666-+

Gurrala R, Lang Z, Shepherd L, et al., 2016, Novel pH sensing semiconductor for point-of-care detection of HIV-1 viremia, Scientific Reports, Vol:6, ISSN:2045-2322

Stanaway JD, Flaxman AD, Naghavi M, et al., 2016, The global burden of viral hepatitis from 1990 to 2013: findings from the Global Burden of Disease Study 2013, The Lancet, Vol:388, ISSN:0140-6736, Pages:1081-1088

Simmons B, Saleem J, Hill A, et al., 2016, Risk of Late Relapse or Reinfection With Hepatitis C Virus After Achieving a Sustained Virological Response: A Systematic Review and Meta-analysis, Clinical Infectious Diseases, Vol:62, ISSN:1058-4838, Pages:683-694

Simmons B, Saleem J, Heath K, et al., 2015, Long-Term Treatment Outcomes of Patients Infected With Hepatitis C Virus: A Systematic Review and Meta-analysis of the Survival Benefit of Achieving a Sustained Virological Response, Clinical Infectious Diseases, Vol:61, ISSN:1058-4838, Pages:730-740

van de Ven N, Fortunak J, Simmons B, et al., 2015, Minimum Target Prices for Production of Direct-Acting Antivirals and Associated Diagnostics to Combat Hepatitis C Virus, Hepatology, Vol:61, ISSN:1527-3350, Pages:1174-1182

Rao VB, Johari N, du Cros P, et al., 2015, Hepatitis C seroprevalence and HIV co-infection in sub-Saharan Africa: a systematic review and meta-analysis, Lancet Infectious Diseases, Vol:15, ISSN:1473-3099, Pages:819-824

Hill A, Cooke G, 2014, Hepatitis C can be cured globally, but at what cost?, Science, Vol:345, ISSN:0036-8075, Pages:141-142

Messina JP, Humphreys I, Flaxman A, et al., 2015, Global Distribution and Prevalence of Hepatitis C Virus Genotypes, Hepatology, Vol:61, ISSN:0270-9139, Pages:77-87

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