Imperial College London

ProfessorGadFrankel

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Molecular Pathogenesis
 
 
 
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Contact

 

+44 (0)20 7594 5253g.frankel

 
 
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Location

 

1.46Flowers buildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

223 results found

Girard F, Batisson I, Frankel GM, Harel J, Fairbrother JMet al., 2005, Interaction of enteropathogenic and Shiga toxin-producing Escherichia coli and porcine intestinal mucosa: Role of intimin and Tir in adherence, INFECTION AND IMMUNITY, Vol: 73, Pages: 6005-6016, ISSN: 0019-9567

JOURNAL ARTICLE

Liu WC, Jenkins C, Shaw DJ, Matthews L, Pearce MC, Low JC, Gunn GJ, Smith HR, Frankel G, Woolhouse MEJet al., 2005, Modelling the epidemiology of Verocytotoxin-producing Escherichia coli serogroups in young calves, EPIDEMIOLOGY AND INFECTION, Vol: 133, Pages: 449-458, ISSN: 0950-2688

JOURNAL ARTICLE

Marches O, Wiles S, Dziva F, La Ragione RM, Schuller S, Best A, Phillips AD, Hartland EL, Woodward MJ, Stevens MP, Frankel Get al., 2005, Characterization of two non-locus of enterocyte effacement-encoded type III-translocated effectors, NleC and NleD, in attaching and effacing pathogens, INFECTION AND IMMUNITY, Vol: 73, Pages: 8411-8417, ISSN: 0019-9567

JOURNAL ARTICLE

Mundy R, MacDonald TT, Dougan G, Frankel G, Wiles Set al., 2005, Citrobacter rodentium of mice and man, CELLULAR MICROBIOLOGY, Vol: 7, Pages: 1697-1706, ISSN: 1462-5814

JOURNAL ARTICLE

Ramboarina S, Fernandes PJ, Daniell S, Islam S, Simpson P, Frankel G, Booy F, Donnenberg MS, Matthews Set al., 2005, Structure of the bundle-forming pilus from enteropathogenic Escherichia coli, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 280, Pages: 40252-40260, ISSN: 0021-9258

JOURNAL ARTICLE

Shaw RK, Cleary J, Murphy MS, Frankel G, Knutton Set al., 2005, Interaction of enteropathogenic Escherichia coli with human intestinal mucosa: Role of effector proteins in brush border remodeling and formation of attaching and effacing lesions, INFECTION AND IMMUNITY, Vol: 73, Pages: 1243-1251, ISSN: 0019-9567

JOURNAL ARTICLE

Shaw RK, Smollett K, Cleary J, Garmendia J, Straatman-Iwanowska A, Frankel G, Knutton Set al., 2005, Enteropathogenic Escherichia coli type III effectors EspG and EspG2 disrupt the microtubule network of intestinal epithelial cells, INFECTION AND IMMUNITY, Vol: 73, Pages: 4385-4390, ISSN: 0019-9567

JOURNAL ARTICLE

Wiles S, Clare S, Harker J, Huett A, Young D, Dougan G, Frankel Get al., 2005, Organ-specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium (vol 6, pg 963, 2004), CELLULAR MICROBIOLOGY, Vol: 7, Pages: 459-459, ISSN: 1462-5814

JOURNAL ARTICLE

Wiles S, Dougan G, Frankel G, 2005, Emergence of a 'hyperinfectious' bacterial state after passage of Citrobacter rodentium through the host gastrointestinal tract, CELLULAR MICROBIOLOGY, Vol: 7, Pages: 1163-1172, ISSN: 1462-5814

JOURNAL ARTICLE

Batchelor M, Guignot J, Patel A, Cummings N, Cleary J, Knutton S, Holden DW, Connerton I, Frankel Get al., 2004, Involvement of the intermediate filament protein cytokeratin-18 in actin pedestal formation during EPEC infection, EMBO REPORTS, Vol: 5, Pages: 104-109, ISSN: 1469-221X

JOURNAL ARTICLE

Cleary J, Lai LC, Shaw RK, Straatman-Iwanowska A, Donnenberg MS, Frankel G, Knutton Set al., 2004, Enteropathogenic Escherichia coli (EPEC) adhesion to intestinal epithelial cells: role of bundle-forming pili (BFP), EspA filaments and intimin, MICROBIOLOGY-SGM, Vol: 150, Pages: 527-538, ISSN: 1350-0872

JOURNAL ARTICLE

Dahan S, Knutton S, Shaw RK, Crepin VF, Dougan G, Frankel Get al., 2004, Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes, INFECTION AND IMMUNITY, Vol: 72, Pages: 5452-5459, ISSN: 0019-9567

JOURNAL ARTICLE

Garmendia J, Phillips AD, Carlier MF, Chong YW, Schuller S, Marches O, Dahan S, Oswald E, Shaw RK, Knutton S, Frankel Get al., 2004, TccP is an enterohaemorrhagic Escherichia coli O157 : H7 type III effector protein that couples Tir to the actin-cytoskeleton, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 1167-1183, ISSN: 1462-5814

JOURNAL ARTICLE

Haque A, Bowe F, Fitzhenry RJ, Frankel G, Thomson M, Heuschkel R, Murch S, Stevens MP, Wallis TS, Phillips AD, Dougan Get al., 2004, Early interactions of Salmonella enterica serovar typhimurium with human small intestinal epithelial explants, GUT, Vol: 53, Pages: 1424-1430, ISSN: 0017-5749

JOURNAL ARTICLE

Li CKF, Pender SLF, Pickard KM, Chance V, Holloway JA, Huett A, Goncalves NS, Mudgett JS, Dougan G, Frankel G, MacDonald TTet al., 2004, Impaired immunity to intestinal bacterial infection in stromelysin-1 (matrix metalloproteinase-3)-deficient mice, JOURNAL OF IMMUNOLOGY, Vol: 173, Pages: 5171-5179, ISSN: 0022-1767

JOURNAL ARTICLE

Mundy R, Jenkins C, Yu J, Smith H, Frankel Get al., 2004, Distribution of espl among clinical enterohaemorrhagic and enteropathogenic Escherichia coli isolates, JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 53, Pages: 1145-1149, ISSN: 0022-2615

JOURNAL ARTICLE

Mundy R, Petrovska L, Smollett K, Simpson N, Wilson RK, Yu J, Tu XL, Rosenshine I, Clare S, Dougan G, Frankel Get al., 2004, Identification of a novel Citrobacter rodentium type III secreted protein, EspI, and roles of this and other secreted proteins in infection, INFECTION AND IMMUNITY, Vol: 72, Pages: 2288-2302, ISSN: 0019-9567

JOURNAL ARTICLE

O'Connell CB, Creasey EA, Knutton S, Elliott S, Crowther LJ, Luo WS, Albert MJ, Kaper JB, Frankel G, Donnenberg MSet al., 2004, SepL, a protein required for enteropathogenic Escherichia coli type III translocation, interacts with secretion component SepD, MOLECULAR MICROBIOLOGY, Vol: 52, Pages: 1613-1625, ISSN: 0950-382X

JOURNAL ARTICLE

Pearce MC, Jenkins C, Vali L, Smith AW, Knight HI, Cheasty T, Smith HR, Gunn GJ, Woolhouse MEJ, Amyes SGB, Frankel Get al., 2004, Temporal shedding patterns and virulence factors of Escherichia coli serogroups O26, O103, O111, O145, and O157 in a cohort of beef calves and their dams, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol: 70, Pages: 1708-1716, ISSN: 0099-2240

JOURNAL ARTICLE

Petrovska L, Aspinall RJ, Barber L, Clare S, Simmons CP, Stratford R, Khan SA, Lemoine NR, Frankel G, Holden DW, Dougan Get al., 2004, Salmonella enterica serovar Typhimurium interaction with dendritic cells: impact of the sifA gene, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 1071-1084, ISSN: 1462-5814

JOURNAL ARTICLE

Prasannan S, Simpson P, Wilson RK, Crepin VF, Frankel G, Matthews Set al., 2004, Letter to the Editor: H-1, C-13, and N-15 resonance assignments of the EscJ protein, a structural component of the Type III secretion system of enteropathogenic E-coli (EPEC), JOURNAL OF BIOMOLECULAR NMR, Vol: 30, Pages: 387-388, ISSN: 0925-2738

JOURNAL ARTICLE

Ramboarina S, Fernandes P, Simpson P, Frankel G, Donnenberg M, Matthews Set al., 2004, Letter to the Editor: Complete resonance assignments of bundlin (BfpA) from the bundle-forming pilus of enteropathogenic Escherichia coli, JOURNAL OF BIOMOLECULAR NMR, Vol: 29, Pages: 427-428, ISSN: 0925-2738

JOURNAL ARTICLE

Schuller S, Frankel G, Phillips AD, 2004, Interaction of Shiga toxin from Escherichia coli with human intestinal epithelial cell lines and explants: Stx2 induces epithelial damage in organ culture, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 289-301, ISSN: 1462-5814

JOURNAL ARTICLE

Shamaei-Tousi A, Cahill R, Frankel G, 2004, Interaction between protein subunits of the type IV secretion system of Bartonella henselae, JOURNAL OF BACTERIOLOGY, Vol: 186, Pages: 4796-4801, ISSN: 0021-9193

JOURNAL ARTICLE

Shaw DJ, Jenkins C, Pearce MC, Cheasty T, Gunn GJ, Dougan G, Smith HR, Woolhouse AEJ, Frankel Get al., 2004, Shedding patterns of verocytotoxin-producing Escherichia coli strains in a cohort of calves and their dams on a Scottish beef farm, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol: 70, Pages: 7456-7465, ISSN: 0099-2240

JOURNAL ARTICLE

Wiles S, Clare S, Harker J, Huett A, Young D, Dougan G, Frankel Get al., 2004, Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium, CELLULAR MICROBIOLOGY, Vol: 6, Pages: 963-972, ISSN: 1462-5814

JOURNAL ARTICLE

Zhang LH, Chaudhuri RR, Constantinidou C, Hobman JL, Patel MD, Jones AC, Sarti D, Roe AJ, Vlisidou I, Shaw RK, Falciani F, Stevens MP, Gally DL, Knutton S, Frankel G, Penn CW, Pallen MJet al., 2004, Regulators encoded in the Escherichia coli type III secretion system 2 gene cluster influence expression of genes within the locus for enterocyte effacement in enterohemorrhagic E. coli O157 : H7, INFECTION AND IMMUNITY, Vol: 72, Pages: 7282-7293, ISSN: 0019-9567

JOURNAL ARTICLE

Creasey EA, Delahay RM, Bishop AA, Shaw RK, Kenny B, Knutton S, Frankel Get al., 2003, CesT is a bivalent enteropathogenic Escherichia coli chaperone required for translocation of both Tir and Map, MOLECULAR MICROBIOLOGY, Vol: 47, Pages: 209-221, ISSN: 0950-382X

JOURNAL ARTICLE

Creasey EA, Delahay RM, Daniell SJ, Frankel Get al., 2003, Yeast two-hybrid system survey of interactions between LEE-encoded proteins of enteropathogenic Escherichia coli, MICROBIOLOGY-SGM, Vol: 149, Pages: 2093-2106, ISSN: 1350-0872

JOURNAL ARTICLE

Creasey EA, Friedberg D, Shaw RK, Umanski T, Knutton S, Rosenshine I, Frankel Get al., 2003, CesAB is an enteropathogenic Escherichia coli chaperone for the type-III translocator proteins EspA and EspB, MICROBIOLOGY-SGM, Vol: 149, Pages: 3639-3647, ISSN: 1350-0872

JOURNAL ARTICLE

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