Imperial College London

ProfessorGadFrankel

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Molecular Pathogenesis
 
 
 
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Contact

 

+44 (0)20 7594 5253g.frankel

 
 
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Location

 

1.46Flowers buildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

221 results found

Fitzhenry RJ, Stevens MP, Jenkins C, Wallis TS, Heuschkel R, Murch S, Thomson M, Frankel G, Phillips ADet al., 2003, Human intestinal tissue tropism of intimin epsilon O103 Escherichia coli, FEMS MICROBIOLOGY LETTERS, Vol: 218, Pages: 311-316, ISSN: 0378-1097

JOURNAL ARTICLE

Goncalves NS, Hale C, Dougan G, Frankel G, MacDonald TTet al., 2003, Binding of intimin from enteropathogenic Escherichia coli to lymphocytes and its functional consequences, INFECTION AND IMMUNITY, Vol: 71, Pages: 2960-2965, ISSN: 0019-9567

JOURNAL ARTICLE

Jenkins C, Lawson AJ, Cheasty T, Willshaw GA, Wright P, Dougan G, Frankel G, Smith HRet al., 2003, Subtyping intimin genes from enteropathogenic Escherichia coli associated with outbreaks and sporadic cases in the United Kingdom and Eire, MOLECULAR AND CELLULAR PROBES, Vol: 17, Pages: 149-156, ISSN: 0890-8508

JOURNAL ARTICLE

Jenkins C, Pearce MC, Smith AW, Knight HI, Shaw DJ, Cheasty T, Foster G, Gunn GJ, Dougan G, Smith HR, Frankel Get al., 2003, Detection of Escherichia coli serogroups O26, O103, O111 and O145 from bovine faeces using immunomagnetic separation and PCR/DNA probe techniques, LETTERS IN APPLIED MICROBIOLOGY, Vol: 37, Pages: 207-212, ISSN: 0266-8254

JOURNAL ARTICLE

Jenkins C, Perry NT, Cheasty T, Shaw DJ, Frankel G, Dougan G, Gunn GJ, Smith HR, Paton AW, Paton JCet al., 2003, Distribution of the saa gene in strains of Shiga toxin-producing Escherzchia coli of human and bovine origins, JOURNAL OF CLINICAL MICROBIOLOGY, Vol: 41, Pages: 1775-1778, ISSN: 0095-1137

JOURNAL ARTICLE

Jenkins C, Willshaw GA, Evans J, Cheasty T, Chart H, Shaw DJ, Dougan G, Frankel G, Smith HRet al., 2003, Subtyping of virulence genes in verocytotoxin-producing Escherichia coli (VTEC) other than serogroup O157 associated with disease in the United Kingdom, JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 52, Pages: 941-947, ISSN: 0022-2615

JOURNAL ARTICLE

MacDonald TT, Frankel G, Dougan G, Goncalves NS, Simmons Cet al., 2003, Host defences to Citrobacter rodentium, INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, Vol: 293, Pages: 87-93, ISSN: 1438-4221

JOURNAL ARTICLE

Mundy R, Pickard D, Wilson RK, Simmons CP, Dougan G, Frankel Get al., 2003, Identification of a novel type IV pilus gene cluster required for gastrointestinal colonization of Citrobacter rodentium, MOLECULAR MICROBIOLOGY, Vol: 48, Pages: 795-809, ISSN: 0950-382X

JOURNAL ARTICLE

Neves BC, Mundy R, Petrovska L, Dougan G, Knutton S, Frankel Get al., 2003, CesD2 of enteropathogenic Escherichia coli is a second chaperone for the type III secretion translocator protein EspD, INFECTION AND IMMUNITY, Vol: 71, Pages: 2130-2141, ISSN: 0019-9567

JOURNAL ARTICLE

Neves BC, Shaw RK, Frankel G, Knutton Set al., 2003, Polymorphisms within EspA filaments of enteropathogenic and enterohemorrhagic Escherichia coli, INFECTION AND IMMUNITY, Vol: 71, Pages: 2262-2265, ISSN: 0019-9567

JOURNAL ARTICLE

Simmons CP, Clare S, Ghaem-Maghami M, Uren TK, Rankin J, Huett A, Goldin R, Lewis DJ, MacDonald TT, Strugnell RA, Frankel G, Dougan Get al., 2003, Central role for B lymphocytes and CD4(+) T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium, INFECTION AND IMMUNITY, Vol: 71, Pages: 5077-5086, ISSN: 0019-9567

JOURNAL ARTICLE

West NP, Sansonetti PJ, Frankel G, Tang CMet al., 2003, Finding your niche: what has been learnt from STM studies on GI colonization, TRENDS IN MICROBIOLOGY, Vol: 11, Pages: 338-344, ISSN: 0966-842X

JOURNAL ARTICLE

Arencibia I, Frankel G, Sundqvist KG, 2002, Induction of cell death in T lymphocytes by invasin via beta(1)-integrin, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 32, Pages: 1129-1138, ISSN: 0014-2980

JOURNAL ARTICLE

Delahay RM, Frankel G, 2002, Coiled-coil proteins associated with type III secretion systems: a versatile domain revisited, MOLECULAR MICROBIOLOGY, Vol: 45, Pages: 905-916, ISSN: 0950-382X

JOURNAL ARTICLE

Delahay RM, Shaw RK, Elliott SJ, Kaper JB, Knutton S, Frankel Get al., 2002, Functional analysis of the enteropathogenic Escherichia coli type III secretion system chaperone CesT identifies domains that mediate substrate interactions, MOLECULAR MICROBIOLOGY, Vol: 43, Pages: 61-73, ISSN: 0950-382X

JOURNAL ARTICLE

Fitzhenry RJ, Pickard DJ, Hartland EL, Reece S, Dougan G, Phillips AD, Frankel Get al., 2002, Intimin type influences the site of human intestinal mucosa colonisation by enterohaemorrhagic Escherichia coli O157 : H7, GUT, Vol: 50, Pages: 180-185, ISSN: 0017-5749

JOURNAL ARTICLE

Fitzhenry RJ, Reece S, Trabulsi LR, Heuschkel R, Murch S, Thomson A, Frankel G, Phillips ADet al., 2002, Tissue tropism of enteropathogenic Escherichia coli strains belonging to the O55 serogroup, INFECTION AND IMMUNITY, Vol: 70, Pages: 4362-4368, ISSN: 0019-9567

JOURNAL ARTICLE

Jenkins C, Chart H, Cheasty T, Willshaw GA, Pearce MC, Foster G, Gunn GJ, Smith HR, Dougan G, Synge BA, Frankel Get al., 2002, Verocytotoxin-producing Escherichia coli (VTEC) other than serogroup O157 from Scottish cattle, VETERINARY RECORD, Vol: 151, Pages: 58-60, ISSN: 0042-4900

JOURNAL ARTICLE

Jenkins C, Pearce MC, Chart H, Cheasty T, Willshaw GA, Gunn GJ, Dougan G, Smith HR, Synge BA, Frankel Get al., 2002, An eight-month study of a population of verocytotoxigenic Escherichia coli (VTEC) in a Scottish cattle herd, JOURNAL OF APPLIED MICROBIOLOGY, Vol: 93, Pages: 944-953, ISSN: 1364-5072

JOURNAL ARTICLE

Knutton S, Shaw R, Frankel G, 2002, Interaction of enteropathogenic Escherichia coli with red blood cell monolayers, BACTERIAL PATHOGENESIS, PT C, Vol: 358, Pages: 350-355, ISSN: 0076-6879

JOURNAL ARTICLE

Li CKF, Goncalves NS, Bachler M, Chance V, Mudgett J, Dougan G, Frankel G, Pender SLF, MacDonald TTet al., 2002, Critical role of stromelysin-1 (MMP-3) in mucosal T cell responses during Citrobacter rodentium infection in mice, GASTROENTEROLOGY, Vol: 122, Pages: A272-A272, ISSN: 0016-5085

JOURNAL ARTICLE

Reece S, Simmons CP, Fitzhenry RJ, Batchelor M, Hale C, Matthews S, Phillips AD, Dougan G, Frankel Get al., 2002, Mutagenesis of conserved tryptophan residues within the receptor-binding domain of intimin: influence on binding activity and virulence, MICROBIOLOGY-SGM, Vol: 148, Pages: 657-665, ISSN: 1350-0872

JOURNAL ARTICLE

Reece S, Simmons CP, Fitzhenry RJ, Ghaem-Maghami M, Mundy R, Hale C, Matthews S, Dougan G, Phillips AD, Frankel Get al., 2002, Tyrosine residues at the immunoglobulin-C-type lectin inter-domain boundary of intimin are not involved in Tir-binding but implicated in colonisation of the host, MICROBES AND INFECTION, Vol: 4, Pages: 1389-1399, ISSN: 1286-4579

JOURNAL ARTICLE

Shaw RK, Daniell S, Frankel G, Knutton Set al., 2002, Enteropathogenic Escherichia coli translocate Tir and form an intimin-Tir intimate attachment to red blood cell membranes, MICROBIOLOGY-SGM, Vol: 148, Pages: 1355-1365, ISSN: 1350-0872

JOURNAL ARTICLE

Simmons CP, Goncalves NS, Ghaem-Maghami M, Bajaj-Elliott M, Clare S, Neves B, Frankel G, Dougan G, MacDonald TTet al., 2002, Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma, JOURNAL OF IMMUNOLOGY, Vol: 168, Pages: 1804-1812, ISSN: 0022-1767

JOURNAL ARTICLE

Stevens MP, Marches O, Campbell J, Huter V, Frankel G, Phillips AD, Oswald E, Wallis TSet al., 2002, Intimin, tir, and Shiga toxin 1 do not influence enteropathogenic responses to Shiga toxin-producing Escherichia coli in bovine ligated intestinal loops, INFECTION AND IMMUNITY, Vol: 70, Pages: 945-952, ISSN: 0019-9567

JOURNAL ARTICLE

Stevens MP, van Diemen PM, Frankel G, Phillips AD, Wallis TSet al., 2002, Efa1 influences colonization of the bovine intestine by Shiga toxin-producing Escherichia coli serotypes O5 and O111, INFECTION AND IMMUNITY, Vol: 70, Pages: 5158-5166, ISSN: 0019-9567

JOURNAL ARTICLE

Daniell SJ, Delahay RM, Shaw RK, Hartland EL, Pallen MJ, Booy F, Ebel F, Knutton S, Frankel Get al., 2001, Coiled-coil domain of enteropathogenic Escherichia coli type III secreted protein EspD is involved in EspA filament-mediated cell attachment and hemolysis, INFECTION AND IMMUNITY, Vol: 69, Pages: 4055-4064, ISSN: 0019-9567

JOURNAL ARTICLE

Daniell SJ, Takahashi N, Wilson R, Friedberg D, Rosenshine I, Booy FP, Shaw RK, Knutton S, Frankel G, Aizawa Set al., 2001, The filamentous type III secretion translocon of enteropathogenic Escherichia coli, CELLULAR MICROBIOLOGY, Vol: 3, Pages: 865-871, ISSN: 1462-5814

JOURNAL ARTICLE

Delahay RM, Frankel G, Knutton S, 2001, Intimate interactions of enteropathogenic Escherichia coli at the host cell surface, CURRENT OPINION IN INFECTIOUS DISEASES, Vol: 14, Pages: 559-565, ISSN: 0951-7375

JOURNAL ARTICLE

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