Imperial College London

ProfessorGaryFrost

Faculty of MedicineDepartment of Medicine

Chair in Nutrition and Dietetics
 
 
 
//

Contact

 

+44 (0)20 3313 8037g.frost Website

 
 
//

Location

 

Commonwealth BiuldingHammersmith HospitalHammersmith Campus

//

Summary

 

Publications

Publication Type
Year
to

351 results found

Wong MCY, Lee WTK, Wong JSY, Frost G, Lodge Jet al., 2008, An approach towards method development for untargeted urinary metabolite profiling in metabonomic research using UPLC/QToF MS, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, Vol: 871, Pages: 341-348, ISSN: 1570-0232

JOURNAL ARTICLE

, 2008, Influence of body mass index on prescribing costs and potential cost savings of a weight management programme in primary care, Journal of Health Services Research & Policy, Vol: 13, Pages: 158-166, ISSN: 1355-8196

JOURNAL ARTICLE

Brynes AE, Frost GS, 2007, Increased sucrose intake is not associated with a change in glucose or insulin sensitivity in people with type 2 diabetes, INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, Vol: 58, Pages: 644-651, ISSN: 0963-7486

JOURNAL ARTICLE

Frost G, Masters K, King C, Kelly M, Hasan U, Heavens P, White R, Stanford Jet al., 2007, A new method of energy prescription to improve weight loss, JOURNAL OF HUMAN NUTRITION AND DIETETICS, Vol: 20, Pages: 152-156, ISSN: 0952-3871

JOURNAL ARTICLE

Grace C, Begum R, Subhani S, Frost G, Greenhalgh T, Kopelman Pet al., 2007, Understanding roadblocks to physical activity participation in a UK South Asian community: cultural and religious perspectives, 15th European Congress on Obesity, Publisher: NATURE PUBLISHING GROUP, Pages: S194-S194, ISSN: 0307-0565

CONFERENCE PAPER

Grace C, Begumt R, Subhani S, Frost G, Greenhalgh T, Kopelman Pet al., 2007, 'Fate depends on deeds': community and religious perspectives on diabetes prevention in a British Bangladeshi population, DIABETIC MEDICINE, Vol: 24, Pages: 27-27, ISSN: 0742-3071

JOURNAL ARTICLE

Jebb SA, Frost G, Griffin B, Lovegrove J, Moore C, Sanders T, Williams Cet al., 2007, The RISCK study: Testing the impact of the amount and type of dietary fat and carbohydrate on metabolic risk, Nutrition Bulletin, Vol: 32, Pages: 154-156, ISSN: 1471-9827

JOURNAL ARTICLE

Jesudason DR, Monteiro MP, McGowan BMC, Neary NM, Park AJ, Philippou E, Small CJ, Frost GS, Ghatei MA, Bloom SRet al., 2007, Low-dose pancreatic polypeptide inhibits food intake in man, BRITISH JOURNAL OF NUTRITION, Vol: 97, Pages: 426-429, ISSN: 0007-1145

JOURNAL ARTICLE

Kelly SAM, Summerbell CD, Brynes A, Whittaker V, Frost Get al., 2007, Wholegrain cereals for coronary heart disease, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

JOURNAL ARTICLE

Martin NM, Small CJ, Lee JL, Ellis S, Dhillo WS, Smith KL, Kong WM, Frost GS, Bloom SRet al., 2007, Low-dose oral tri-iodothyronine does not directly increase food intake in man, DIABETES OBESITY & METABOLISM, Vol: 9, Pages: 435-437, ISSN: 1462-8902

JOURNAL ARTICLE

McGough C, Baidwint C, Hackett C, Wedlake L, Norman A, Frost G, Blake P, Tai D, Khoo V, Harrington K, Andreyev HJNet al., 2007, A randomised controlled trial of elemental diet during pelvic radiotherapy, CLINICAL ONCOLOGY, Vol: 19, Pages: S11-S11, ISSN: 0936-6555

JOURNAL ARTICLE

McGough C, Wedlake L, Hackett C, Norman A, Frost G, Blake P, Tait D, Khoo V, Harrington K, Andreyev HJNet al., 2007, Use of simple biological markers to monitor gastrointestinal toxicity during pelvic radiotherapy, CLINICAL ONCOLOGY, Vol: 19, Pages: S39-S39, ISSN: 0936-6555

JOURNAL ARTICLE

Milton JE, Briche B, Brown IJ, Hickson M, Robertson CE, Frost GSet al., 2007, Relationship of glycaemic index with cardiovascular risk factors: analysis of the National Diet and Nutrition Survey for people aged 65 and older, PUBLIC HEALTH NUTRITION, Vol: 10, Pages: 1321-1335, ISSN: 1368-9800

JOURNAL ARTICLE

Milton JE, Sananthanan CS, Patterson M, Ghatei MA, Bloom SR, Frost GSet al., 2007, Glucagon-like peptide-1 (7-36) amide response to low versus high glycaemic index preloads in overweight subjects with and without type II diabetes mellitus, EUROPEAN JOURNAL OF CLINICAL NUTRITION, Vol: 61, Pages: 1364-1372, ISSN: 0954-3007

JOURNAL ARTICLE

Moore C, Gitau R, Frost GS, Griffin BA, Jebb SA, Sanders TA, Lovegrove JAet al., 2007, Strategy to alter the amount and composition of dietary carbohydrate and fat in free-living individuals participating in the RISCK trial, PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 66, Pages: 86A-86A, ISSN: 0029-6651

JOURNAL ARTICLE

Mosdol A, Witte DR, Frost G, Marmot MG, Brunner EJet al., 2007, Dietary glycemic index and glycemic load are associated with high-density-lipoprotein cholesterol at baseline but not with increased risk of diabetes in the Whitehall II study, AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol: 86, Pages: 988-994, ISSN: 0002-9165

JOURNAL ARTICLE

Nematy M, Brynes AE, Hornick PI, Patterson M, Ghatei MA, Bloom SR, Brett SJ, Frost GSet al., 2007, Postprandial ghrelin suppression is exaggerated following major surgery; implications for nutritional recovery, Nutrition & Metabolism, Vol: 4, ISSN: 1743-7075

JOURNAL ARTICLE

Philippou E, Neary NM, Chaudhri OB, Brynes AE, Dornhorst A, Leeds AR, Hickson M, Frost GSet al., 2007, Modest improvements in weight maintenance on a low-glycaemic index (G1) diet following weight loss in overweight and obese subjects, PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 66, Pages: 75A-75A, ISSN: 0029-6651

JOURNAL ARTICLE

So P-W, Yu W-S, Kuo Y-T, Wasserfall C, Goldstone AP, Bell JD, Frost Get al., 2007, Impact of Resistant Starch on Body Fat Patterning and Central Appetite Regulation, PLOS ONE, Vol: 2, ISSN: 1932-6203

JOURNAL ARTICLE

Wong MCY, Feldmann H, Frost G, Lodge Jet al., 2007, Nutritional metabonomics: optimisation for general serum metabolic profiling using ultraperformance liquid chromatography (UPLC) coupled with quadrupole orthogonal acceleration time-of-flight, PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 66, Pages: 110A-110A, ISSN: 0029-6651

JOURNAL ARTICLE

Baldwin C, McGough C, Norman AR, Frost GS, Cunningham DC, Andreyev HJNet al., 2006, Failure of dietetic referral in patients with gastrointestinal cancer and weight loss, EUROPEAN JOURNAL OF CANCER, Vol: 42, Pages: 2504-2509, ISSN: 0959-8049

JOURNAL ARTICLE

McGough C, Baldwin C, Norman A, Frost G, Blake P, Tait D, Khoo V, Harrington K, Andreyev HJNet al., 2006, Is supplementation with elemental diet feasible in patients undergoing pelvic radiotherapy?, CLINICAL NUTRITION, Vol: 25, Pages: 109-116, ISSN: 0261-5614

JOURNAL ARTICLE

McGough C, Peacock N, Hackett C, Baldwin C, Norman A, Frost G, Blake P, Tait D, Khoo V, Harrington K, Whelan K, Andreyev HJNet al., 2006, Taste preferences for oral nutrition supplements in patients before and after pelvic radiotherapy: A double-blind controlled study, CLINICAL NUTRITION, Vol: 25, Pages: 906-912, ISSN: 0261-5614

JOURNAL ARTICLE

Mead A, Van Goor A, Keightley H, Fox K, Frost Get al., 2006, Dietary improvements and impact on weight reduction in patients attending a cardiac prevention and rehabilitation programme: A longitudinal study, Annual Scientific Conference of the British-Society-Promoting-Cardiovascular-Health, Publisher: B M J PUBLISHING GROUP, Pages: A55-A56, ISSN: 1355-6037

CONFERENCE PAPER

Nematy M, Brynes AE, Hornick PI, Brett SJ, Frost GSet al., 2006, Postprandial ghrelin suppression is exaggerated following major surgery; implications for nutritional recovery., PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 65, Pages: 63A-63A, ISSN: 0029-6651

JOURNAL ARTICLE

Nematy M, Hickson M, Brynes AE, Charles PJ, Frost GSet al., 2006, Appetite controlling gut hormone release during acute exacerbation of chronic obstructive pulmonary disease, Winter Meeting of the British-Thoracic-Society/British-Lung-Foundation (BTS/BLF), Publisher: B M J PUBLISHING GROUP, Pages: II87-II87, ISSN: 0040-6376

CONFERENCE PAPER

Nematy M, Hickson M, Brynes AE, Ruxton CHS, Frost GSet al., 2006, Vulnerable patients with a fractured neck of femur: nutritional status and support in hospital, JOURNAL OF HUMAN NUTRITION AND DIETETICS, Vol: 19, Pages: 209-218, ISSN: 0952-3871

JOURNAL ARTICLE

Nematy M, O'Flynn JE, Wandrag L, Brynes AE, Brett SJ, Patterson M, Ghatei MA, Bloom SR, Frost GSet al., 2006, Changes in appetite related gut hormones in intensive care unit patients: a pilot cohort study, CRITICAL CARE, Vol: 10, ISSN: 1466-609X

JOURNAL ARTICLE

Nematy M, O'Flynn JE, Wandrag L, Brynes AE, Brett SJ, Patterson M, Ghatei MA, Bloom SR, Frost GSet al., 2006, Changes in appetite related gut hormones in intensive care unit patients: a pilot cohort study, Critical care (London, England), Vol: 10

METHODS: Sixteen ICU patients (60 +/- 4.7 years, body mass index (BMI) 28.1 +/- 1.7 kg/m2 (mean +/- standard error of the mean)) underwent fasting blood sample collections on days 1, 3, 5, 14, 21 and 28 of their stay at Hammersmith and Charing Cross Hospitals. Changes in appetite and biochemical and anthropometric markers of nutritional status were recorded. A comparison was made to a group of 36 healthy volunteers matched for age and BMI (54.3 +/- 2.9 years, p = 0.3; BMI 25.8 +/- 0.8 kg/m2 p = 0.2). RESULTS: Compared to healthy subjects, ICU patients exhibited a significantly lower level of ghrelin (day one 297.8 +/- 76.3 versus 827.2 +/- 78.7 pmol/l, p < 0.001) during their stay in the ICU. This tended to rise to the normal level during the last three weeks of hospital stay. Conversely, ICU patients showed a significantly higher level of PYY (day one 31.5 +/- 9.6 versus 11.3 +/- 1.0 pmol/l, p < 0.05) throughout their stay in the ICU and on the ward, with a downward trend to the normal level during the last three weeks of stay. CONCLUSIONS: Results from our study show high levels of PYY and low levels of ghrelin in ICU patients compared to healthy controls. There appears to be a relationship between the level of these gut hormones and nutritional intake. INTRODUCTION: The nutritional status of patients in the intensive care unit (ICU) appears to decline not only during their stay in the ICU but also after discharge from the ICU. Recent evidence suggests that gut released peptides, such as ghrelin and peptide YY (PYY) regulate the initiation and termination of meals and could play a role in the altered eating behaviour of sick patients. The aim of this study was to assess the patterns of ghrelin and PYY levels during the stay of ICU patients in hospital.

JOURNAL ARTICLE

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00330288&limit=30&person=true&page=8&respub-action=search.html