Imperial College London

ProfessorGaryFrost

Faculty of MedicineDepartment of Medicine

Chair in Nutrition and Dietetics
 
 
 
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Contact

 

+44 (0)20 3313 8037g.frost Website

 
 
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Location

 

Commonwealth BiuldingHammersmith HospitalHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

351 results found

Chambers ES, Byrne CS, Aspey K, Chen Y, Khan S, Morrison DJ, Frost Get al., 2018, Acute oral sodium propionate supplementation raises resting energy expenditure and lipid oxidation in fasted humans, DIABETES OBESITY & METABOLISM, Vol: 20, Pages: 1034-1039, ISSN: 1462-8902

JOURNAL ARTICLE

Eriksen R, Gibson R, Lamb K, McMeel Y, Vergnaud A-C, Spear J, Aresu M, Chan Q, Elliott P, Frost Get al., 2018, Nutrient profiling and adherence to components of the UK national dietary guidelines association with metabolic risk factors for CVD and diabetes: Airwave Health Monitoring Study, BRITISH JOURNAL OF NUTRITION, Vol: 119, Pages: 695-705, ISSN: 0007-1145

JOURNAL ARTICLE

Infante JR, Korn RL, Rosen LS, LoRusso P, Dychter SS, Zhu J, Maneval DC, Jiang P, Shepard HM, Frost G, Von Hoff DD, Borad MJ, Ramanathan RKet al., 2018, Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours (vol 118, pg 156, 2018), BRITISH JOURNAL OF CANCER, Vol: 118, ISSN: 0007-0920

JOURNAL ARTICLE

Brooks L, Viardot A, Tsakmaki A, Stolarczyk E, Howard JK, Cani PD, Everard A, Sleeth ML, Psichas A, Anastasovskaj J, Bell JD, Bell-Anderson K, Mackay CR, Ghatei MA, Bloom SR, Frost G, Bewick GAet al., 2017, Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety, MOLECULAR METABOLISM, Vol: 6, Pages: 48-60, ISSN: 2212-8778

JOURNAL ARTICLE

Brown A, Guess N, Dornhorst A, Taheri S, Frost Get al., 2017, Insulin-associated weight gain in obese type 2 diabetes mellitus patients: What can be done?, DIABETES OBESITY & METABOLISM, Vol: 19, Pages: 1655-1668, ISSN: 1462-8902

JOURNAL ARTICLE

Cheung W, Keski-Rahkonen P, Assi N, Ferrari P, Freisling H, Rinaldi S, Slimani N, Zamora-Ros R, Rundle M, Frost G, Gibbons H, Carr E, Brennan L, Cross AJ, Pala V, Panico S, Sacerdote C, Palli D, Tumino R, Kuehn T, Kaaks R, Boeing H, Floegel A, Mancini F, Boutron-Ruault M-C, Baglietto L, Trichopoulou A, Naska A, Orfanos P, Scalbert Aet al., 2017, A metabolomic study of biomarkers of meat and fish intake, AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol: 105, Pages: 600-608, ISSN: 0002-9165

JOURNAL ARTICLE

Clar C, Al-Khudairy L, Loveman E, Kelly SAM, Hartley L, Flowers N, Germano R, Frost G, Rees Ket al., 2017, Low glycaemic index diets for the prevention of cardiovascular disease, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

JOURNAL ARTICLE

Fiamoncini J, Yiorkas AM, Gedrich K, Rundle M, Alsters SI, Roeselers G, van den Broek TJ, Clavel T, Lagkouvardos I, Wopereis S, Frost G, van Ommen B, Blakemore AI, Daniel Het al., 2017, Determinants of postprandial plasma bile acid kinetics in human volunteers, AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, Vol: 313, Pages: G300-G312, ISSN: 0193-1857

JOURNAL ARTICLE

Garcia Perez I, Posma JM, Gibson R, Chambers ES, Nicholson JK, Holmes E, Frost Get al., 2017, MODERNIZING DIETARY ASSESSMENT, Publisher: KARGER, Pages: 286-287, ISSN: 0250-6807

CONFERENCE PAPER

Garcia-Perez I, Posma JM, Gibson R, Chambers ES, Hansen TH, Vestergaard H, Hansen T, Beckmann M, Pedersen O, Elliott P, Stamler J, Nicholson JK, Draper J, Mathers JC, Holmes E, Frost Get al., 2017, Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial, LANCET DIABETES & ENDOCRINOLOGY, Vol: 5, Pages: 184-195, ISSN: 2213-8587

JOURNAL ARTICLE

Gibbons H, Michielsen CJR, Rundle M, Frost G, McNulty BA, Nugent AP, Walton J, Flynn A, Gibney MJ, Brennan Let al., 2017, Demonstration of the utility of biomarkers for dietary intake assessment; proline betaine as an example, MOLECULAR NUTRITION & FOOD RESEARCH, Vol: 61, ISSN: 1613-4125

JOURNAL ARTICLE

Gibson R, Eriksen R, Lamb K, McMeel Y, Vergnaud A-C, Spear J, Aresu M, Chan Q, Elliott P, Frost Get al., 2017, Dietary assessment of British police force employees: a description of diet record coding procedures and cross-sectional evaluation of dietary energy intake reporting (The Airwave Health Monitoring Study), BMJ OPEN, Vol: 7, ISSN: 2044-6055

JOURNAL ARTICLE

Gibson R, Eriksen R, Singh D, Vergnaud A-C, Heard A, Chan Q, Elliott P, Frost Get al., 2017, A cross-sectional investigation into the occupational and socio-demographic characteristics of British police force employees reporting a dietary pattern associated with cardiometabolic risk: findings from the Airwave Health Monitoring Study., Eur J Nutr

PURPOSE: The aims of this study were to (1) determine the association between diet quality using the Dietary Approaches to Stop Hypertension (DASH) score and cardiometabolic risk in a British working population and (2) identify employee characteristics associated with reporting a poorer quality dietary pattern. METHODS: British police employees enrolled (2007-2012) into the Airwave Health Monitoring Study (n = 5527) were included for sex-specific cross-sectional analyses. Dietary intakes were measured using 7-day food records. DASH score was calculated to determine diet quality. Logistic regression evaluated associations between (1) diet quality and increased cardiometabolic risk (defined as ≥ 3 risk markers: dyslipidaemia, elevated blood pressure, waist circumference, CRP or HbA1c), and (2) poor diet quality (lowest fifth of DASH score distribution) and employee characteristics. RESULTS: Employees recording a poor diet quality had greater odds (OR) of increased cardiometabolic risk independent of established risk factors (demographic, lifestyle and occupational) and BMI: men OR 1.50 (95% CI 1.12-2.00), women: OR 1.84 (95% CI 1.19-2.97) compared to the healthiest diet group. Characteristics associated with reporting a poor quality diet were employment in Scotland vs. England: men OR 1.88 (95% CI 1.53-2.32), women: OR 1.49 (95% CI 1.11-2.00), longer working hours (≥ 49 vs. ≤40 h) men: OR 1.53 (95% CI 1.21-1.92) women: OR 1.53 (95% CI 1.12-2.09). For men, job strain (high vs. low) was associated with reporting a poor diet quality OR 1.66 (95% CI 1.30-2.12). CONCLUSIONS: The general population disparities in diet quality between England and Scotland were reflected in British police employees. The association of longer working hours and job strain with diet quality supports the targeting of workplace nutritional interventions.

JOURNAL ARTICLE

Kelly SAM, Hartley L, Loveman E, Colquitt JL, Jones HM, Al-Khudairy L, Clar C, Germano R, Lunn HR, Frost G, Rees Ket al., 2017, Whole grain cereals for the primary or secondary prevention of cardiovascular disease, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

JOURNAL ARTICLE

O'Gorman A, Gibbons H, Ryan MF, Gibney ER, Gibney MJ, Frost GS, Roche HM, Brennan Let al., 2017, Exploring the Links between Diet and Health in an Irish Cohort: A Lipidomic Approach, JOURNAL OF PROTEOME RESEARCH, Vol: 16, Pages: 1280-1287, ISSN: 1535-3893

JOURNAL ARTICLE

Petropoulou K, Salt L, Warren F, Domoney C, Wilde P, Frost Get al., 2017, A seed trait studied by gregor mendel in pisum Sativum L. (PEA): Potential prevention of type 2 diabetes, Legumes for Global Food Security, Pages: 129-156, ISBN: 9781536122794

© 2017 Nova Science Publishers, Inc. Pulses have been attracting much interest in recent years from academia, industry and the general public. The attraction has been driven largely by the health benefits that pulses offer compared with refined, processed cereal based foods, coupled with the clear low environmental impact of these crops [1, 2]. Although the consumption of pulses is only a small fraction of that of staple crops such as wheat, maize and rice, the popularity of pulse foods is increasing, particularly in developed countries [3]. In the UK, consumer trends are moving towards a more varied diet, bringing in alternative sources of protein, carbohydrate and micronutrients and a move away from conventional cereals. Although some of these trends are based upon little or no rigorous scientific evidence, there are some clear health benefits associated with consumption of certain pulses. In this article, we will describe one such benefit that is the focus of a collaborative research programme which aims to improve our knowledge from basic plant science and genetics, through processing and consumption of foods and the physiological basis of associated health benefits. The programme aims to study how the type of starch contained in naturally occurring variants of pea seeds can help prevent the onset of type 2 diabetes. The specific aim is to understand how, through manipulating starch biosynthesis, the amount of fermentable carbohydrates reaching the bacterial community in the human colon might be increased. Fermentation of this carbohydrate is thought to produce metabolites which improve our ability to control blood sugar levels.

BOOK CHAPTER

Pingitore A, Chambers ES, Hill T, Maldonado IR, Liu B, Bewick G, Morrison DJ, Preston T, Wallis GA, Tedford C, Gonzalez RC, Huang GC, Choudhary P, Frost G, Persaud SJet al., 2017, The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro, DIABETES OBESITY & METABOLISM, Vol: 19, Pages: 257-265, ISSN: 1462-8902

JOURNAL ARTICLE

Pingitore A, Maldonado IR, Abuin NG, Liu B, Bewick GA, Huang G, Frost G, Persaud SJet al., 2017, Short-chain fatty acids potentiate insulin secretion and protect against apoptosis in mouse and human islets; role of FFAR2, 53rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Publisher: SPRINGER, Pages: S67-S67, ISSN: 0012-186X

CONFERENCE PAPER

Posma JM, Garcia-Perez I, Heaton JC, Burdisso P, Mathers JC, Draper J, Lewis M, Lindon JC, Frost G, Holmes E, Nicholson JKet al., 2017, Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers, ANALYTICAL CHEMISTRY, Vol: 89, Pages: 3300-3309, ISSN: 0003-2700

JOURNAL ARTICLE

Rahman S, Vorkas P, Morrison D, Frost G, Haskard D, Woollard Ket al., 2017, ACUTE DIETARY SATURATED FAT INTAKE CAN SUPPRESS THE INFLAMMATORY RESPONSE IN HUMAN CIRCULATING FOAMY MONOCYTES, 85th Congress of the European-Atherosclerosis-Society (EAS), Publisher: ELSEVIER IRELAND LTD, Pages: E116-E116, ISSN: 0021-9150

CONFERENCE PAPER

Umpleby AM, Shojaee-Moradie F, Fielding B, Li X, Marino A, Alsini N, Isherwood C, Jackson N, Ahmad A, Stolinski M, Lovegrove JA, Johnsen S, Mendis ASJR, Wright J, Wilinska ME, Hovorka R, Bell JD, Thomas EL, Frost GS, Griffin BAet al., 2017, Impact of liver fat on the differential partitioning of hepatic triacylglycerol into VLDL subclasses on high and low sugar diets, CLINICAL SCIENCE, Vol: 131, Pages: 2561-+, ISSN: 0143-5221

JOURNAL ARTICLE

Yin X, Gibbons H, Rundle M, Frost G, McNulty BA, Nugent AP, Walton J, Flynn A, Gibney MJ, Brennan Let al., 2017, Estimation of Chicken Intake by Adults Using Metabolomics-Derived Markers, JOURNAL OF NUTRITION, Vol: 147, Pages: 1850-1857, ISSN: 0022-3166

JOURNAL ARTICLE

Albar SA, Alwan NA, Evans CEL, Greenwood DC, Cade JEet al., 2016, Agreement between an online dietary assessment tool (myfood24) and an interviewer-administered 24-h dietary recall in British adolescents aged 11-18 years, BRITISH JOURNAL OF NUTRITION, Vol: 115, Pages: 1678-1686, ISSN: 0007-1145

JOURNAL ARTICLE

Beckmann M, Joosen AM, Clarke MM, Mugridge O, Frost G, Engel B, Taillart K, Lloyd AJ, Draper J, Lodge JKet al., 2016, Changes in the human plasma and urinary metabolome associated with acute dietary exposure to sucrose and the identification of potential biomarkers of sucrose intake, MOLECULAR NUTRITION & FOOD RESEARCH, Vol: 60, Pages: 444-457, ISSN: 1613-4125

JOURNAL ARTICLE

Bottin JH, Swann JR, Cropp E, Chambers ES, Ford HE, Ghatei MA, Frost GSet al., 2016, Mycoprotein reduces energy intake and postprandial insulin release without altering glucagon-like peptide-1 and peptide tyrosine-tyrosine concentrations in healthy overweight and obese adults: a randomised-controlled trial, BRITISH JOURNAL OF NUTRITION, Vol: 116, Pages: 360-374, ISSN: 0007-1145

JOURNAL ARTICLE

Boyd SE, Charani E, Lyons T, Frost G, Holmes AHet al., 2016, Information provision for antibacterial dosing in the obese patient: a sizeable absence?, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Vol: 71, Pages: 3588-3592, ISSN: 0305-7453

JOURNAL ARTICLE

Brown AC, Taheri S, Dornhorst A, Kapoor N, McGowan B, Leeds AR, Frost Get al., 2016, Using a low energy formula diet in obese patients with long-standing insulin-treated Type 2 diabetes produces significantly greater weight loss, improvement in glucose control and insulin reductions compared to gold standard clinical care over a 12 week period, DIABETIC MEDICINE, Vol: 33, Pages: 69-69, ISSN: 0742-3071

JOURNAL ARTICLE

Byrne CS, Chambers ES, Alhabeeb H, Chhina N, Morrison DJ, Preston T, Tedford C, Fitzpatrick J, Irani C, Busza A, Garcia-Perez I, Fountana S, Holmes E, Goldstone AP, Frost GSet al., 2016, Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods, AMERICAN JOURNAL OF CLINICAL NUTRITION, Vol: 104, Pages: 5-14, ISSN: 0002-9165

JOURNAL ARTICLE

Carter MC, Hancock N, Albar SA, Brown H, Greenwood DC, Hardie LJ, Frost GS, Wark PA, Cade JEet al., 2016, Development of a New Branded UK Food Composition Database for an Online Dietary Assessment Tool, NUTRIENTS, Vol: 8, ISSN: 2072-6643

JOURNAL ARTICLE

Darzi J, Frost GS, Swann JR, Costabile A, Robertson MDet al., 2016, L-rhamnose as a source of colonic propionate inhibits insulin secretion but does not influence measures of appetite or food intake, APPETITE, Vol: 98, Pages: 142-149, ISSN: 0195-6663

JOURNAL ARTICLE

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