Publications
521 results found
McGough C, Wedlake L, Hackett C, et al., 2007, Use of simple biological markers to monitor gastrointestinal toxicity during pelvic radiotherapy, CLINICAL ONCOLOGY, Vol: 19, Pages: S39-S39, ISSN: 0936-6555
McGough C, Baidwint C, Hackett C, et al., 2007, A randomised controlled trial of elemental diet during pelvic radiotherapy, CLINICAL ONCOLOGY, Vol: 19, Pages: S11-S11, ISSN: 0936-6555
Jesudason DR, Monteiro MP, McGowan BMC, et al., 2007, Low-dose pancreatic polypeptide inhibits food intake in man, BRITISH JOURNAL OF NUTRITION, Vol: 97, Pages: 426-429, ISSN: 0007-1145
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- Citations: 59
Grace C, Begumt R, Subhani S, et al., 2007, 'Fate depends on deeds': community and religious perspectives on diabetes prevention in a British Bangladeshi population, DIABETIC MEDICINE, Vol: 24, Pages: 27-27, ISSN: 0742-3071
Kelly SAM, Summerbell CD, Brynes A, et al., 2007, Wholegrain cereals for coronary heart disease, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X
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- Citations: 57
Brynes AE, Frost GS, 2007, Increased sucrose intake is not associated with a change in glucose or insulin sensitivity in people with type 2 diabetes, INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, Vol: 58, Pages: 644-651, ISSN: 0963-7486
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- Citations: 5
Moore C, Gitau R, Frost GS, et al., 2007, Strategy to alter the amount and composition of dietary carbohydrate and fat in free-living individuals participating in the RISCK trial, PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 66, Pages: 86A-86A, ISSN: 0029-6651
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- Citations: 1
Wong MCY, Feldmann H, Frost G, et al., 2007, Nutritional metabonomics: optimisation for general serum metabolic profiling using ultraperformance liquid chromatography (UPLC) coupled with quadrupole orthogonal acceleration time-of-flight, PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 66, Pages: 110A-110A, ISSN: 0029-6651
Philippou E, Neary NM, Chaudhri OB, et al., 2007, Modest improvements in weight maintenance on a low-glycaemic index (G1) diet following weight loss in overweight and obese subjects, PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 66, Pages: 75A-75A, ISSN: 0029-6651
Wynne K, Park AJ, Small CJ, et al., 2006, Oxyntomodulin increases energy expenditure in addition to decreasing energy intake in overweight and obese humans: a randomised controlled trial, INTERNATIONAL JOURNAL OF OBESITY, Vol: 30, Pages: 1729-1736, ISSN: 0307-0565
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- Citations: 251
Nematy M, Hickson M, Brynes AE, et al., 2006, Appetite controlling gut hormone release during acute exacerbation of chronic obstructive pulmonary disease, Winter Meeting of the British-Thoracic-Society/British-Lung-Foundation (BTS/BLF), Publisher: B M J PUBLISHING GROUP, Pages: II87-II87, ISSN: 0040-6376
McGough C, Peacock N, Hackett C, et al., 2006, Taste preferences for oral nutrition supplements in patients before and after pelvic radiotherapy: A double-blind controlled study, CLINICAL NUTRITION, Vol: 25, Pages: 906-912, ISSN: 0261-5614
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- Citations: 18
Nematy M, Powell CA, Brynes AE, et al., 2006, Peptide YY (PYY) is increased in elderly patients with femoral neck fractures: A prospective cohort study, JOURNAL OF PARENTERAL AND ENTERAL NUTRITION, Vol: 30, Pages: 530-531, ISSN: 0148-6071
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- Citations: 1
Baldwin C, McGough C, Norman AR, et al., 2006, Failure of dietetic referral in patients with gastrointestinal cancer and weight loss, EUROPEAN JOURNAL OF CANCER, Vol: 42, Pages: 2504-2509, ISSN: 0959-8049
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- Citations: 38
Thomas EL, Brynes AE, Hamilton G, et al., 2006, Effect of nutritional counselling on hepatic, muscle and adipose tissue fat content and distribution in non-alcoholic fatty liver disease, WORLD JOURNAL OF GASTROENTEROLOGY, Vol: 12, Pages: 5813-5819, ISSN: 1007-9327
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- Citations: 88
Nematy M, Hickson M, Brynes AE, et al., 2006, Vulnerable patients with a fractured neck of femur: nutritional status and support in hospital, JOURNAL OF HUMAN NUTRITION AND DIETETICS, Vol: 19, Pages: 209-218, ISSN: 0952-3871
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- Citations: 34
Mead A, Van Goor A, Keightley H, et al., 2006, Dietary improvements and impact on weight reduction in patients attending a cardiac prevention and rehabilitation programme: A longitudinal study, Annual Scientific Conference of the British-Society-Promoting-Cardiovascular-Health, Publisher: B M J PUBLISHING GROUP, Pages: A55-A56, ISSN: 1355-6037
Patel AD, Stanley SA, Murphy KG, et al., 2006, Ghrelin stimulates insulin-induced glucose uptake in adipocytes, REGULATORY PEPTIDES, Vol: 134, Pages: 17-22, ISSN: 0167-0115
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- Citations: 62
Nematy M, O'Flynn JE, Wandrag L, et al., 2006, Changes in appetite related gut hormones in intensive care unit patients: a pilot cohort study, Critical care (London, England), Vol: 10
METHODS: Sixteen ICU patients (60 +/- 4.7 years, body mass index (BMI) 28.1 +/- 1.7 kg/m2 (mean +/- standard error of the mean)) underwent fasting blood sample collections on days 1, 3, 5, 14, 21 and 28 of their stay at Hammersmith and Charing Cross Hospitals. Changes in appetite and biochemical and anthropometric markers of nutritional status were recorded. A comparison was made to a group of 36 healthy volunteers matched for age and BMI (54.3 +/- 2.9 years, p = 0.3; BMI 25.8 +/- 0.8 kg/m2 p = 0.2). RESULTS: Compared to healthy subjects, ICU patients exhibited a significantly lower level of ghrelin (day one 297.8 +/- 76.3 versus 827.2 +/- 78.7 pmol/l, p < 0.001) during their stay in the ICU. This tended to rise to the normal level during the last three weeks of hospital stay. Conversely, ICU patients showed a significantly higher level of PYY (day one 31.5 +/- 9.6 versus 11.3 +/- 1.0 pmol/l, p < 0.05) throughout their stay in the ICU and on the ward, with a downward trend to the normal level during the last three weeks of stay. CONCLUSIONS: Results from our study show high levels of PYY and low levels of ghrelin in ICU patients compared to healthy controls. There appears to be a relationship between the level of these gut hormones and nutritional intake. INTRODUCTION: The nutritional status of patients in the intensive care unit (ICU) appears to decline not only during their stay in the ICU but also after discharge from the ICU. Recent evidence suggests that gut released peptides, such as ghrelin and peptide YY (PYY) regulate the initiation and termination of meals and could play a role in the altered eating behaviour of sick patients. The aim of this study was to assess the patterns of ghrelin and PYY levels during the stay of ICU patients in hospital.
McGough C, Baldwin C, Norman A, et al., 2006, Is supplementation with elemental diet feasible in patients undergoing pelvic radiotherapy?, CLINICAL NUTRITION, Vol: 25, Pages: 109-116, ISSN: 0261-5614
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- Citations: 11
Wright L, Hickson M, Frost G, 2006, Eating together is important: using a dining room in an acute elderly medical ward increases energy intake, JOURNAL OF HUMAN NUTRITION AND DIETETICS, Vol: 19, Pages: 23-26, ISSN: 0952-3871
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- Citations: 66
Philippou E, Milton JE, Brynes AE, et al., 2006, An exploration into the proportion of carbohydrate used in the calculation of diet glycaemic index (GI) for which GI values are published or estimated., PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 65, Pages: 59A-59A, ISSN: 0029-6651
Nematy M, Brynes AE, Hornick PI, et al., 2006, Postprandial ghrelin suppression is exaggerated following major surgery; implications for nutritional recovery., PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 65, Pages: 63A-63A, ISSN: 0029-6651
Philippou E, McGowan B, Brynes AE, et al., 2006, The effect of a 12-week low-glycaemic index diet on heart disease risk factors and 24 h glucose profile in healthy middle-aged volunteers at risk of heart disease: a pilot study., PROCEEDINGS OF THE NUTRITION SOCIETY, Vol: 65, Pages: 59A-59A, ISSN: 0029-6651
Nematy M, O'Flynn JE, Wandrag L, et al., 2005, Changes in appetite related gut hormones in intensive care unit patients: a pilot cohort study, Critical Care, Vol: 10, ISSN: 1364-8535
INTRODUCTION:The nutritional status of patients in the intensive care unit (ICU) appears to decline not only during their stay in the ICU but also after discharge from the ICU. Recent evidence suggests that gut released peptides, such as ghrelin and peptide YY (PYY) regulate the initiation and termination of meals and could play a role in the altered eating behaviour of sick patients. The aim of this study was to assess the patterns of ghrelin and PYY levels during the stay of ICU patients in hospital.METHODS:Sixteen ICU patients (60 +/- 4.7 years, body mass index (BMI) 28.1 +/- 1.7 kg/m2 (mean +/- standard error of the mean)) underwent fasting blood sample collections on days 1, 3, 5, 14, 21 and 28 of their stay at Hammersmith and Charing Cross Hospitals. Changes in appetite and biochemical and anthropometric markers of nutritional status were recorded. A comparison was made to a group of 36 healthy volunteers matched for age and BMI (54.3 +/- 2.9 years, p = 0.3; BMI 25.8 +/- 0.8 kg/m2 p = 0.2).RESULTS:Compared to healthy subjects, ICU patients exhibited a significantly lower level of ghrelin (day one 297.8 +/- 76.3 versus 827.2 +/- 78.7 pmol/l, p < 0.001) during their stay in the ICU. This tended to rise to the normal level during the last three weeks of hospital stay. Conversely, ICU patients showed a significantly higher level of PYY (day one 31.5 +/- 9.6 versus 11.3 +/- 1.0 pmol/l, p < 0.05) throughout their stay in the ICU and on the ward, with a downward trend to the normal level during the last three weeks of stay.CONCLUSIONS:Results from our study show high levels of PYY and low levels of ghrelin in ICU patients compared to healthy controls. There appears to be a relationship between the level of these gut hormones and nutritional intake.
Rahemtulla Z, Baldwin C, Spiro A, et al., 2005, The palatability of milk-based and non-milk-based nutritional supplements in gastrointestinal cancer and the effect of chemotherapy, CLINICAL NUTRITION, Vol: 24, Pages: 1029-1037, ISSN: 0261-5614
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- Citations: 38
Neary NM, Small CJ, Druce MR, et al., 2005, Peptide YY<sub>3-36</sub> and glucagon-like peptide-1<sub>7-36</sub> inhibit food intake additively, ENDOCRINOLOGY, Vol: 146, Pages: 5120-5127, ISSN: 0013-7227
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- Citations: 271
O'Flynn J, Peake H, Hickson M, et al., 2005, The prevalence of malnutrition in hospitals can be reduced: Results from three consecutive cross-sectional studies, CLINICAL NUTRITION, Vol: 24, Pages: 1078-1088, ISSN: 0261-5614
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- Citations: 98
Gibbs H, Broom J, Brown F, et al., 2005, The impact of obesity on drug prescribing in primary care, BRITISH JOURNAL OF GENERAL PRACTICE, Vol: 55, Pages: 743-749, ISSN: 0960-1643
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- Citations: 55
Druce MR, Wren AM, Park AJ, et al., 2005, Ghrelin increases food intake in obese as well as lean subjects, INTERNATIONAL JOURNAL OF OBESITY, Vol: 29, Pages: 1130-1136, ISSN: 0307-0565
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- Citations: 280
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