Imperial College London

ProfessorGavinScreaton

Faculty of MedicineDepartment of Immunology and Inflammation

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 1190g.screaton Website

 
 
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Assistant

 

Ms Claire Puddephatt +44 (0)20 7594 1190

 
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Location

 

2.15Faculty BuildingSouth Kensington Campus

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Summary

 

Summary

Professor Gavin Screaton was appointed to the Chair of Medicine at Imperial College in 2004. The Department of Medicine has recently been restructured and houses over 900 research and support staff with activities housed in 5 divisions: Brain Sciences; Infectious Diseases; Experimental Medicine; Diabetes, Endocrinology & Metabolism, and Immunology & Inflammation.

Professor Screaton received his first degree from Cambridge in 1984 before moving on to Oxford to complete his medical studies in 1987. He then completed training in General Internal medicine and obtained a DPhil from Oxford University in 1998. His research, which has been supported by a series of Fellowships awarded by the MRC and Wellcome Trust, has covered a variety of topics from control of RNA processing and apoptosis to immunology. The current interests of his laboratory revolve around the immunology of infectious diseases with a special interest in dengue haemorrhagic fever, where his research is currently funded by the MRC and Wellcome Trust, with active research collaborations in South-East Asia.

Professor Screaton is a Fellow of the Academy of Medical Sciences, a Fellow of the Royal College of Physicians, a member of the Association of Physicians and was made a Founder Senior Investigator in the National Institute for Health Research. He also sits on funding panels at the Wellcome Trust and MRC.

Publications

Journals

Slon-Campos JL, Dejnirattisai W, Jagger BW, et al., 2019, A protective Zika virus E-dimer-based subunit vaccine engineered to abrogate antibody-dependent enhancement of dengue infection, Nature Immunology, Vol:20, ISSN:1529-2908, Pages:1291-+

Salazar V, Jagger BW, Mongkolsapaya J, et al., 2019, Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice, Cell Reports, Vol:26, ISSN:2211-1247, Pages:1585-+

Tsai W-Y, Chen H-L, Tsai J-J, et al., 2018, Potent Neutralizing Human Monoclonal Antibodies Preferentially Target Mature Dengue Virus Particles: Implication for Novel Strategy for Dengue Vaccine, Journal of Virology, Vol:92, ISSN:0022-538X

Campos JLS, Mongkolsapaya J, Screaton GR, 2018, The immune response against flaviviruses, Nature Immunology, Vol:19, ISSN:1529-2908, Pages:1189-1198

Renner M, Flanagan A, Dejnirattisai W, et al., 2018, Characterization of a potent and highly unusual minimally enhancing antibody directed against dengue virus, Nature Immunology, Vol:19, ISSN:1529-2908, Pages:1248-+

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