Imperial College London


Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Clinical Professor of Endocrinology



+44 (0)20 3313 1383graham.williams




10N5Commonwealth BuildingHammersmith Campus





Graham Williams became Professor of Endocrinology at Imperial College London in 2005.  He obtained a BSc in Anatomy and MBBS from St. Thomas’s Hospital, University of London and a PhD from the University of Birmingham.  He trained as a Howard Hughes Medical Institute Fellow at Harvard Medical School, Boston, USA and as a Medical Research Council Training Fellow and Clinician Scientist Fellow at the University of Birmingham.  He was appointed as Senior Lecturer at the Royal Postgraduate Medical School, London (1995) and received an MRC Career Establishment Award.  He was promoted to Reader (2000) and subsequently Professor (2005).

Professor Williams is Head of the Molecular Endocrinology Laboratory in the Department of Medicine at Hammersmith Campus.  His research focuses on the (i) genetic origins of bone and cartilage disease and (ii) molecular mechanisms of thyroid hormone action during skeletal development and in adult bone maintenance and tissue repair.  This research is internationally recognised and the laboratory is generously funded by a Wellcome Trust Strategic Award, MRC Research Grant, European Commission Horizon 2020 Award and Wellcome Trust Investigator Award.  Professor Williams receives regular invitations to speak at international scientific meetings all over the world and the laboratory collaborates widely throughout the UK, Europe, USA and Asia.  Clinical Training Fellows, PhD students and post-doctoral scientists in the Molecular Endocrinology Group have received 42 prizes for research excellence.

Professor Williams was awarded the Society for Endocrinology Medal (2011), Bermuda Hospitals Board Edwin B. Astwood Memorial Lecture (2011), European Thyroid Association Merck Serono Prize (2012), Danish Thyroid Association Distinguished Annual Lectureship Award (2014), American Thyroid Association Sidney H. Ingbar Distinguished Lectureship Award (2014), British Thyroid Association Pitt-Rivers Medal (2016) and European Calcified Tissue Society Steven Boonen Clinical Research Award (2018).  He received a Wellcome Trust Investigator Award (2016-2021).

Professor Williams was elected as President of the Society for Endocrinology (2016-2019) and as Treasurer and a Member of Council (2010-2016).  He was President of the British Thyroid Association (2011-2014), and sat as a member of the British Thyroid Association Executive (2003-2009 & 2011-2015) and the European Thyroid Association Executive Committee (2008-2011).

Professor Williams has served on numerous Editorial Boards, Grant Review Panels and Scientific Programme Organising Committees over the years and became an elected Fellow of the Academy of Medical Sciences in 2019.



Joustra SD, Roelfsema F, van Trotsenburg ASP, et al., 2020, IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction, Journal of Clinical Endocrinology & Metabolism, Vol:105, ISSN:0021-972X, Pages:E70-E84

Leitch VD, Bassett JHD, Williams GR, 2020, Role of thyroid hormones in craniofacial development, Nature Reviews Endocrinology, Vol:16, ISSN:1759-5029, Pages:147-164

Leitch VD, Brassill MJ, Rahman S, et al., 2019, PYY is a negative regulator of bone mass and strength, Bone, Vol:127, ISSN:8756-3282, Pages:427-435

Beck-Cormier S, Lelliott CJ, Logan JG, et al., 2019, Slc20a2, encoding the phosphate transporter PiT2, is a novel genetic determinant of bone quality and strength, Journal of Bone and Mineral Research, Vol:34, ISSN:1523-4681, Pages:1101-1114

Freudenthal B, Shetty S, Butterfield NC, et al., 2019, Genetic and pharmacological targeting of transcriptional repression in resistance to thyroid hormone alpha, Thyroid, Vol:29, ISSN:1050-7256

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