My research group studies the molecular basis of immune cell development and function. We are particularly interested in the role of the E4bp4/Nfil3 gene in NK cell development and both the function and role of the Mll gene in haematopoietic stem cell self-renewal and immune cell development.
et al., 2018, Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs, Science Signaling, Vol:11, ISSN:1945-0877
et al., 2018, Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development, Journal of Immunology, Vol:200, ISSN:0022-1767, Pages:1370-1381
Male V, Brady HJM, 2017, COMMENTARY Murine thymic NK cells: A case of identity, European Journal of Immunology, Vol:47, ISSN:0014-2980, Pages:797-799
et al., 2017, Constitutive expression of the anti-apoptotic Bcl-2 family member A1 in murine endothelial cells leads to transplant tolerance, Clinical and Experimental Immunology, Vol:188, ISSN:0009-9104, Pages:219-225
et al., 2016, Adipose Natural Killer Cells Regulate Adipose Tissue Macrophages to Promote Insulin Resistance in Obesity, Cell Metabolism, Vol:23, ISSN:1550-4131, Pages:685-698