Imperial College London

Professor Hugh JM Brady

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Immunology
 
 
 
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Contact

 

+44 (0)20 7594 3777h.brady

 
 
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Location

 

504Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

My research group studies the molecular basis of immune cell development and function.  We are particularly interested in the role of the E4bp4/Nfil3 gene in NK cell development and both the function and role of the Mll gene in haematopoietic stem cell self-renewal and immune cell development.

Publications

Journals

Rätsep MT, Moore SD, Jafri S, et al., 2018, Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency., Am J Physiol Lung Cell Mol Physiol, Vol:315, Pages:L977-L990

Rollings CM, Sinclair LV, Brady HJM, et al., 2018, Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs, Science Signaling, Vol:11, ISSN:1945-0877

Kostrzewski T, Borg AJ, Meng Y, et al., 2018, Multiple levels of control determine how E4bp4/Nfil3 regulates NK cell development, Journal of Immunology, Vol:200, ISSN:1550-6606, Pages:1370-1381

Male V, Brady HJM, 2017, Murine thymic NK cells: a case of identity, European Journal of Immunology, Vol:47, ISSN:0014-2980, Pages:797-799

Smyth LA, Meader L, Xiao F, et al., 2017, Constitutive expression of the anti-apoptotic Bcl-2 family member A1 in murine endothelial cells leads to transplant tolerance, Clinical and Experimental Immunology, Vol:188, ISSN:1365-2249, Pages:219-225

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