Imperial College London

Professor Hugh JM Brady

Faculty of Natural SciencesDepartment of Life Sciences

Professor of Immunology



+44 (0)20 7594 3777h.brady




504Sir Alexander Fleming BuildingSouth Kensington Campus





My research group studies the molecular basis of immune cell development and function.  We are particularly interested in the role of the E4bp4/Nfil3 gene in NK cell development and both the function and role of the Mll gene in haematopoietic stem cell self-renewal and immune cell development.



Kostrzewski T, Borg AJ, Meng Y, et al., 2018, Multiple Levels of Control Determine How E4bp4/Nfil3 Regulates NK Cell Development, Journal of Immunology, Vol:200, ISSN:0022-1767, Pages:1370-1381

Male V, Brady HJM, 2017, COMMENTARY Murine thymic NK cells: A case of identity, European Journal of Immunology, Vol:47, ISSN:0014-2980, Pages:797-799

Smyth LA, Meader L, Xiao F, et al., 2017, Constitutive expression of the anti-apoptotic Bcl-2 family member A1 in murine endothelial cells leads to transplant tolerance, Clinical and Experimental Immunology, Vol:188, ISSN:0009-9104, Pages:219-225

Lee B-C, Kim M-S, Pae M, et al., 2016, Adipose Natural Killer Cells Regulate Adipose Tissue Macrophages to Promote Insulin Resistance in Obesity, Cell Metabolism, Vol:23, ISSN:1550-4131, Pages:685-698

Boulenouar S, Doisne J-M, Sferruzzi-Perri A, et al., 2016, The Residual Innate Lymphoid Cells in NFIL3-Deficient Mice Support Suboptimal Maternal Adaptations to Pregnancy, Frontiers in Immunology, Vol:7, ISSN:1664-3224

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