Imperial College London
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Dr Harriet Kemp

Faculty of Medicine, Department of Surgery & Cancer

Clinical Lecturer
 
 
 
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Contact

 

h.kemp

 
 
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Location

 

Chelsea and Westminster HospitalChelsea and Westminster Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kemp:2017:bja/aex124,
author = {Kemp, HI and Cook, TM and Thomas, M and Harper, NJN},
doi = {bja/aex124},
journal = {BRITISH JOURNAL OF ANAESTHESIA},
pages = {132--139},
title = {UK anaesthetists' perspectives and experiences of severe perioperative anaphylaxis: NAP6 baseline survey},
url = {http://dx.doi.org/10.1093/bja/aex124},
volume = {119},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: There is limited information on UK anaesthetists’ perspectives and experiences of perioperative anaphylaxis. This baseline survey of the Sixth National Audit Project (NAP6) aimed to identify relevant departmental preparedness and practices, and individual experiences, perceptions and drug-avoidance patterns.Methods: All anaesthetists in 356 UK NHS hospitals were invited to complete an electronic survey.Results: 11 104 anaesthetists (77% crude response rate) from 341 (96%) hospitals responded. Most had immediate access to guidelines for anaphylaxis treatment (87%) and established referral pathways for investigation (82%), but a minority reported access to designated treatment packs (37%) or an anaphylaxis lead (35%). Anaesthetists reported 1734 cases of suspected perioperative anaphylaxis in 2014–5 of which 81% were referred for specialist investigation and 14% reported to the Medicines and Healthcare Products Regulatory Agency (MHRA). In their career, 76% of respondents had seen a case of perioperative anaphylaxis (1:7.25 years of practice) and 4% reported a death (1:311 years of practice), equivalent to 2.3% of events being fatal. Agents most frequently perceived to cause anaphylaxis were antibiotics, particularly penicillins, and neuromuscular blocking agents, notably rocuronium. Suxamethonium and penicillins were avoided by a higher proportion of respondents than events attributed to these drugs whereas the converse was true for atracurium and teicoplanin.Conclusions: This is the largest ever survey of anaesthetists’ practices and experiences relating to perioperative anaphylaxis. It identifies gaps in preparedness and referral for further investigation and to the UK MHRA. It provides important data about drugs implicated in such events and anaesthetists’ attitudes to anaphylaxis.
AU  - Kemp,HI
AU  - Cook,TM
AU  - Thomas,M
AU  - Harper,NJN
DO  - bja/aex124
EP  - 139
PY  - 2017///
SN  - 0007-0912
SP  - 132
TI  - UK anaesthetists' perspectives and experiences of severe perioperative anaphylaxis: NAP6 baseline survey
T2  - BRITISH JOURNAL OF ANAESTHESIA
UR  - http://dx.doi.org/10.1093/bja/aex124
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000404260400021&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/50888
VL  - 119
ER  -
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