Overview
Dr Keun's research programme centres on the application of small molecule profiling (metabolomics & small RNA sequencing) to problems in oncology and toxicology . His current work includes:
- using systems biology to understand and exploit post-transcriptional regulation of metabolism by microRNAs and RNA splicing
- identifying translational biomarkers of drug toxicity
- investigating metabolic inhibitors as an anti-cancer therapies
- measuring metabolic risk factors for cancer in population studies
- understanding the links between lifetime environmental exposure ('the exposome') and health outcomes
Dr Keun's research is supported by Cancer Research UK, EU-FP7/Horizon 2020, AstraZeneca/BBSRC Prostate Cancer UK
Collaborators
HANI GABRA, SORA, IC
Guest Lectures
College of Public Health, National Taiwan University, 2013
College of Public Health, National Taiwan University, Taipei, 2013
International Society for the Study of Xenobiotics, Amsterdam, 2012
Session speaker, European Association for Cancer Research (EACR) meeting, Barcelona, Spain, 2012
30th Heidelberg Grand Round, German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ), 2011
Research Student Supervision
Rana,S, Systematic analysis of prognostic and predictive miRNA-mRNA networks in Prostate Cancer