Imperial College London

Professor Hashim Ahmed

Faculty of MedicineDepartment of Surgery & Cancer

Chair in Urology (Clinical)
 
 
 
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Contact

 

hashim.ahmed

 
 
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Location

 

5L28Lab BlockCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

270 results found

Afaq A, Alahmed S, Chen S-H, Lengana T, Haroon A, Payne H, Ahmed H, Punwani S, Sathekge M, Bomanji Jet al., 2018, Impact of Ga-68-Prostate-Specific Membrane Antigen PET/CT on Prostate Cancer Management, JOURNAL OF NUCLEAR MEDICINE, Vol: 59, Pages: 89-92, ISSN: 0161-5505

JOURNAL ARTICLE

Ahmed HU, 2018, Opening Our Eyes to Multiparametric Magnetic Resonance Imaging Before Prostate Biopsy, EUROPEAN UROLOGY, Vol: 73, Pages: 361-362, ISSN: 0302-2838

JOURNAL ARTICLE

Appayya MB, Sidhu HS, Dikaios N, Johnston EW, Simons LAM, Freeman A, Kirkham APS, Ahmed HU, Punwani Set al., 2018, Characterizing indeterminate (Likert-score 3/5) peripheral zone prostate lesions with PSA density, PI-RADS scoring and qualitative descriptors on multiparametric MRI, BRITISH JOURNAL OF RADIOLOGY, Vol: 91, ISSN: 0007-1285

JOURNAL ARTICLE

Bonmati E, Hu Y, Villarini B, Rodell R, Martin P, Han L, Donaldson I, Ahmed HU, Moore CM, Emberton M, Barratt DCet al., 2018, Technical Note: Error metrics for estimating the accuracy of needle/instrument placement during transperineal magnetic resonance/ultrasound-guided prostate interventions, MEDICAL PHYSICS, Vol: 45, Pages: 1408-1414, ISSN: 0094-2405

JOURNAL ARTICLE

Brizmohun Appayya M, Adshead J, Ahmed HU, Allen C, Bainbridge A, Barrett T, Giganti F, Graham J, Haslam P, Johnston EW, Kastner C, Kirkham APS, Lipton A, McNeill A, Moniz L, Moore CM, Nabi G, Padhani AR, Parker C, Patel A, Pursey J, Richenberg J, Staffurth J, van der Meulen J, Walls D, Punwani Set al., 2018, National implementation of multi-parametric magnetic resonance imaging for prostate cancer detection - recommendations from a UK consensus meeting., BJU Int, Vol: 122, Pages: 13-25

OBJECTIVES: To identify areas of agreement and disagreement in the implementation of multi-parametric magnetic resonance imaging (mpMRI) of the prostate in the diagnostic pathway. MATERIALS AND METHODS: Fifteen UK experts in prostate mpMRI and/or prostate cancer management across the UK (involving nine NHS centres to provide for geographical spread) participated in a consensus meeting following the Research and Development Corporation and University of California-Los Angeles (UCLA-RAND) Appropriateness Method, and were moderated by an independent chair. The experts considered 354 items pertaining to who can request an mpMRI, prostate mpMRI protocol, reporting guidelines, training, quality assurance (QA) and patient management based on mpMRI levels of suspicion for cancer. Each item was rated for agreement on a 9-point scale. A panel median score of ≥7 constituted 'agreement' for an item; for an item to reach 'consensus', a panel majority scoring was required. RESULTS: Consensus was reached on 59% of items (208/354); these were used to provide recommendations for the implementation of prostate mpMRI in the UK. Key findings include prostate mpMRI requests should be made in consultation with the urological team; mpMRI scanners should undergo QA checks to guarantee consistently high diagnostic quality scans; scans should only be reported by trained and experienced radiologists to ensure that men with unsuspicious prostate mpMRI might consider avoiding an immediate biopsy. CONCLUSIONS: Our consensus statements demonstrate a set of criteria that are required for the practical dissemination of consistently high-quality prostate mpMRI as a diagnostic test before biopsy in men at risk.

JOURNAL ARTICLE

Chandak P, Byrne N, Lynch H, Allen C, Rottenberg G, Chandra A, Raison N, Ahmed H, Kasivisvanathan V, Elhage O, Dasgupta Pet al., 2018, Three-dimensional printing in robot-assisted radical prostatectomy - an Idea, Development, Exploration, Assessment, Long-term follow-up (IDEAL) Phase 2a study., BJU Int

JOURNAL ARTICLE

Chau EM, Arya M, Petrides N, Aldin Z, Mckenzie J, Emberton M, Virdi J, Ahmed HU, Kasivisvanathan Vet al., 2018, Performance characteristics of multiparametric-MRI at a non-academic hospital using transperineal template mapping biopsy as a reference standard, INTERNATIONAL JOURNAL OF SURGERY OPEN, Vol: 10, Pages: 66-71, ISSN: 2405-8572

JOURNAL ARTICLE

Elliott D, Hamdy FC, Leslie TA, Rosario D, Dudderidge T, Hindley R, Emberton M, Brewster S, Sooriakumaran P, Catto JWF, Emara A, Ahmed H, Whybrow P, le Conte S, Donovan JLet al., 2018, Overcoming difficulties with equipoise to enable recruitment to a randomised controlled trial of partial ablation versus radical prostatectomy for unilateral localised prostate cancer., BJU Int

OBJECTIVE: To describe how clinicians conceptualised equipoise in the PART (Partial prostate Ablation versus Radical prosTatectomy in intermediate risk, unilateral clinically localised prostate cancer) feasibility study and how this affected recruitment. SUBJECTS AND METHODS: PART included a QuinteT Recruitment Intervention (QRI) to optimise recruitment. Phase I aimed to understand recruitment, and included scrutinising recruitment data, interviewing the Trial Management Group and recruiters (n=13), and audio-recording recruitment consultations (n=64). Data were analysed using qualitative content and thematic analysis methods. In Phase II, strategies to improve recruitment were developed and delivered. RESULTS: Initially many recruiters found it difficult to maintain a position of equipoise and held preconceptions about which treatment was best for particular patients. They did not feel comfortable about approaching all eligible patients, and when the study was discussed, biases were conveyed through the use of terminology, poorly balanced information and direct treatment recommendations. Individual and group feedback led to presentations to patients becoming clearer and enabled recruiters to reconsider their sense of equipoise. Although the precise impact of the QRI alone cannot be determined, recruitment increased (from mean 1.4 (range=0-4) to 4.5 (range=0-12) patients per month) and the feasibility study reached its recruitment target. CONCLUSION: Although clinicians find it challenging to recruit participants to a trial comparing different contemporary treatments for prostate cancer, training and support can enable recruiters to become more comfortable with conveying equipoise and providing clearer information to patients. This article is protected by copyright. All rights reserved.

JOURNAL ARTICLE

Faria R, Soares MO, Spackman E, Ahmed HU, Brown LC, Kaplan R, Emberton M, Sculpher MJet al., 2018, Optimising the Diagnosis of Prostate Cancer in the Era of Multiparametric Magnetic Resonance Imaging: A Cost-effectiveness Analysis Based on the Prostate MR Imaging Study (PROMIS), EUROPEAN UROLOGY, Vol: 73, Pages: 23-30, ISSN: 0302-2838

JOURNAL ARTICLE

Faria R, Soares MO, Spackman E, Ahmed HU, Brown LC, Kaplan R, Emberton M, Sculpher MJet al., 2018, Re: Jochen Walz. The "PROMIS" of Magnetic Resonance Imaging Cost Effectiveness in Prostate Cancer Diagnosis? Eur Urol 2018;73:31-2, EUROPEAN UROLOGY, Vol: 73, Pages: E151-E152, ISSN: 0302-2838

JOURNAL ARTICLE

Ganzer R, Arthanareeswaran VKA, Ahmed HU, Cestari A, Rischmann P, Salomon G, Teber D, Liatsikos E, Stolzenburg J-U, Barret Eet al., 2018, Which technology to select for primary focal treatment of prostate cancer?-European Section of Urotechnology (ESUT) position statement., Prostate Cancer Prostatic Dis

BACKGROUND: With growing interest in focal therapy (FT) of prostate cancer (PCa) there is an increasing armamentarium of treatment modalities including high-intensity focused ultrasound (HIFU), cryotherapy, focal laser ablation (FLA), irreversible electroporation (IRE), vascular targeted photodynamic therapy (VTP), focal brachytherapy (FBT) and stereotactic ablative radiotherapy (SABR). Currently there are no clear recommendations as to which of these technologies are appropriate for individual patient characteristics. Our intention was to review the literature for special aspects of the different technologies that might be of advantage depending on individual patient and tumour characteristics. METHODS: The current literature on FT was screened for the following factors: morbidity, repeatability, tumour risk category, tumour location, tumour size and prostate volume and anatomical issues. The ESUT expert panel arrived at consensus regarding a position statement on a structured pathway for available FT technologies based on a combination of the literature and expert opinion. RESULTS: Side effects were low across different studies and FT modalities with urinary continence rates of 90-100% and erectile dysfunction between 5 and 52%. Short to medium cancer control based on post-treatment biopsies were variable between ablative modalities. Expert consensus suggested that posterior lesions are better amenable to FT using HIFU. Cryotherapy provides best possible outcomes for anterior tumours. Apical lesions, when treated with FBT, may yield the least urethral morbidity. CONCLUSIONS: Further prospective trials are required to assess medium to long term disease control of different ablative modalities for FT. Amongst different available FT modalities our ESUT expert consensus suggests that some may be better for diffe`rent tumour locations. Tumour risk, tumour size, tumour location, and prostate volume are all important factors to consider and might aid in designing future

JOURNAL ARTICLE

Giancarlo M, Ploussard G, Ost P, De Visschere PJL, Sooriakumaran P, Briganti A, Gandaglia G, Tilki D, Surcel CI, Tsaur I, Van den Bergh R, Kretschmer A, Borgmann H, Gontero P, Ahmed H, Valerio Met al., 2018, AN INTERNATIONAL SURVEY ABOUT FOCAL THERAPY FOR PROSTATE CANCER FROM THE YOUNG ACADEMIC UROLOGISTS (YAU): THE OPINION OF 484 PHYSICIANS, Publisher: INT INST ANTICANCER RESEARCH, Pages: 2567-2568, ISSN: 0250-7005

CONFERENCE PAPER

Grey A, Scott R, Charman S, van der Meulen J, Frinking P, Acher P, Liyanage S, Madaan S, Constantinescu G, Shah B, Graves CB, Freeman A, Jameson C, Ramachandran N, Emberton M, Arya M, Ahmed HUet al., 2018, The CADMUS trial - Multi-parametric ultrasound targeted biopsies compared to multi-parametric MRI targeted biopsies in the diagnosis of clinically significant prostate cancer, CONTEMPORARY CLINICAL TRIALS, Vol: 66, Pages: 86-92, ISSN: 1551-7144

JOURNAL ARTICLE

Kasivisvanathan V, Ahmed H, Cashman S, Challacombe B, Emberton M, Gao C, Lamb BW, Nambiar A, Pickard R, Shah TT, Smith Det al., 2018, The British Urology Researchers in Surgical Training (BURST) Research Collaborative: an alternative research model for carrying out large scale multi-centre urological studies, BJU INTERNATIONAL, Vol: 121, Pages: 6-9, ISSN: 1464-4096

JOURNAL ARTICLE

Peters M, Kanthabalan A, Shah TT, McCartan N, Moore CM, Arya M, van Zyp JRVDV, Moerland MA, Hindley RG, Emberton M, Ahmed HUet al., 2018, Development and internal validation of prediction models for biochemical failure and composite failure after focal salvage high intensity focused ultrasound for local radiorecurrent prostate cancer: Presentation of risk scores for individual patient prognoses, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, Vol: 36, ISSN: 1078-1439

JOURNAL ARTICLE

Rouhani MJ, Burleigh EJ, Hobbis C, Dunford C, Osman NI, Gan C, Gibbons NB, Ahmed HU, Miah Set al., 2018, UK medical students' perceptions, attitudes, and interest toward medical leadership and clinician managers, ADVANCES IN MEDICAL EDUCATION AND PRACTICE, Vol: 9, Pages: 119-124, ISSN: 1179-7258

JOURNAL ARTICLE

Rouhani MJ, Burleigh EJ, Hobbis C, Dunford C, Osman NI, Gan C, Gibbons NB, Ahmed HU, Miah Set al., 2018, Expanding management and leadership education in medical schools Response, ADVANCES IN MEDICAL EDUCATION AND PRACTICE, Vol: 9, Pages: 277-278, ISSN: 1179-7258

JOURNAL ARTICLE

Shah TT, Peters M, Guillaumier S, Arya M, Afzal N, Hosking-Jervis F, Dudderidge T, Hindley R, Lewi H, McCartan N, Moore CM, Nigam R, Ogden C, Persad R, Shah K, Virdi J, Winkler M, Emberton M, Ahmed HU, Minhas Set al., 2018, PREDICTORS OF POOR FUNCTIONAL OUTCOMES AFTER FOCAL HIGH INTENSITY FOCUSSED ULTRASOUND (HIFU), American-Urological-Association(AUA) Annual Meeting, Publisher: ELSEVIER SCIENCE INC, Pages: E378-E379, ISSN: 0022-5347

CONFERENCE PAPER

Shah TT, Valerio M, Ahmed HU, 2018, Re: Effect of Prior Focal Therapy on Perioperative, Oncologic and Functional Outcomes of Salvage Robotic Assisted Radical Prostatectomy, JOURNAL OF UROLOGY, Vol: 199, Pages: 1634-1635, ISSN: 0022-5347

JOURNAL ARTICLE

Walker NAF, Norris JM, Shah TT, Yap T, Cathcart P, Moore CM, Ahmed HU, Emberton M, Minhas Set al., 2018, A comparison of time taken to return to baseline erectile function following focal and whole gland ablative therapies for localized prostate cancer: A systematic review, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, Vol: 36, Pages: 67-76, ISSN: 1078-1439

JOURNAL ARTICLE

Ahmed HU, Bosaily AE-S, Brown LC, Gabe R, Kaplan R, Parmar MK, Collaco-Moraes Y, Ward K, Hindley RG, Freeman A, Kirkham AP, Oldroyd R, Parker C, Emberton Met al., 2017, Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS): a paired validating confirmatory study, LANCET, Vol: 389, Pages: 815-822, ISSN: 0140-6736

JOURNAL ARTICLE

Ahmed HU, Brown LC, Kaplan R, Parker C, Emberton Met al., 2017, Diagnostic accuracy of the PROMIS study Reply, LANCET, Vol: 390, Pages: 362-362, ISSN: 0140-6736

JOURNAL ARTICLE

Bass EJ, Donaldson IA, Freeman A, Jameson C, Punwani S, Moore C, Arya M, Emberton M, Ahmed HUet al., 2017, Magnetic resonance imaging targeted transperineal prostate biopsy: a local anaesthetic approach, PROSTATE CANCER AND PROSTATIC DISEASES, Vol: 20, Pages: 311-317, ISSN: 1365-7852

JOURNAL ARTICLE

Borghesi M, Ahmed H, Nam R, Schaeffer E, Schiavina R, Taneja S, Weidner W, Loeb Set al., 2017, Complications After Systematic, Random, and Image-guided Prostate Biopsy, EUROPEAN UROLOGY, Vol: 71, Pages: 353-365, ISSN: 0302-2838

JOURNAL ARTICLE

Davda R, Prentice M, Sarova A, Nei W, Orczyk C, Arya M, Moore C, Ahmed H, Emberton M, Mitra A, Payne Het al., 2017, Late Toxicity and Patient Reported Outcomes in Patients Treated With Salvage Radiation Following Primary High Intensity Focal Ultrasound for Localized Prostate Cancer, 59th Annual Meeting of the American-Society-for-Therapeutic-Radiation-Oncology (ASTRO), Publisher: ELSEVIER SCIENCE INC, Pages: E226-E226, ISSN: 0360-3016

CONFERENCE PAPER

Dickinson L, Ahmed HU, Hindley RG, McCartan N, Freeman A, Allen C, Emberton M, Kirkham APet al., 2017, Prostate-specific antigen vs. magnetic resonance imaging parameters for assessing oncological outcomes after high intensity-focused ultrasound focal therapy for localized prostate cancer, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, Vol: 35, ISSN: 1078-1439

JOURNAL ARTICLE

Dikaios N, Atkinson D, Tudisca C, Purpura P, Forster M, Ahmed H, Beale T, Emberton M, Punwani Set al., 2017, A comparison of Bayesian and non-linear regression methods for robust estimation of pharmacokinetics in DCE-MRI and how it affects cancer diagnosis, COMPUTERIZED MEDICAL IMAGING AND GRAPHICS, Vol: 56, Pages: 1-10, ISSN: 0895-6111

JOURNAL ARTICLE

Edison E, Shah TT, Ahmed HU, 2017, Focal Ablation of Early-Stage Prostate Cancer Candidate Selection, Treatment Guidance, and Assessment of Outcome, UROLOGIC CLINICS OF NORTH AMERICA, Vol: 44, Pages: 575-+, ISSN: 0094-0143

JOURNAL ARTICLE

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