Imperial College London

Professor Hashim Ahmed

Faculty of MedicineDepartment of Surgery & Cancer

Chair in Urology (Clinical)
 
 
 
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Contact

 

hashim.ahmed

 
 
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Location

 

5L28Lab BlockCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

270 results found

Lau B, Shah TS, Valerio MV, Ahmed HA, Arya MAet al., 2015, History of cryotherapy for prostate cancer, Annual Meeting of the British-Association-of-Urological-Surgeons (BAUS), Publisher: WILEY-BLACKWELL, Pages: 31-31, ISSN: 1464-4096

CONFERENCE PAPER

Lau B, Shah TT, Valerio M, Hamid S, Ahmed HU, Arya Met al., 2015, Technological aspects of delivering cryotherapy for prostate cancer, EXPERT REVIEW OF MEDICAL DEVICES, Vol: 12, Pages: 183-190, ISSN: 1743-4440

JOURNAL ARTICLE

Orczyk C, Emberton M, Ahmed HU, 2015, What tumours should we treat with focal therapy based on risk category, grade, size and location?, CURRENT OPINION IN UROLOGY, Vol: 25, Pages: 212-219, ISSN: 0963-0643

JOURNAL ARTICLE

Orczyk C, Punwani S, Kirkham A, Ramachandran N, Walkden M, Freeman A, Jameson C, Shehada M, Moore C, Arya M, Emberton M, Ahmed Het al., 2015, [Not Available]., Prog Urol, Vol: 25, Pages: 829-830, ISSN: 1166-7087

JOURNAL ARTICLE

Panagiotaki E, Chan RW, Dikaios N, Ahmed HU, O'Callaghan J, Freeman A, Atkinson D, Punwani S, Hawkes DJ, Alexander DCet al., 2015, Microstructural Characterization of Normal and Malignant Human Prostate Tissue With Vascular, Extracellular, and Restricted Diffusion for Cytometry in Tumours Magnetic Resonance Imaging, INVESTIGATIVE RADIOLOGY, Vol: 50, Pages: 218-227, ISSN: 0020-9996

JOURNAL ARTICLE

Shah TT, Kasivisvanathan V, Jameson C, Freeman A, Emberton M, Ahmed HUet al., 2015, Histological outcomes after focal high-intensity focused ultrasound and cryotherapy, WORLD JOURNAL OF UROLOGY, Vol: 33, Pages: 955-964, ISSN: 0724-4983

JOURNAL ARTICLE

Sivaraman A, Sanchez-Salas R, Ahmed HU, Barret E, Cathala N, Mombet A, Uriburu Pizarro F, Carneiro A, Doizi S, Galiano M, Rozet F, Prapotnich D, Cathelineau Xet al., 2015, Clinical utility of transperineal template-guided mapping biopsy of the prostate after negative magnetic resonance imaging-guided transrectal biopsy., Urol Oncol, Vol: 33, Pages: 329.e7-329.11

PURPOSE: We evaluated the prostate cancer detection with transperineal template-guided mapping biopsy in patients with elevated prostate-specific antigen and negative magnetic resonance imaging (MRI)-guided biopsy. MATERIALS AND METHODS: Totally 75 patients underwent transperineal template-guided mapping biopsy for prior negative MRI-guided (cognitive registration) biopsy during April 2013 to August 2014. Primary objective was to report clinically significant cancer detection in this cohort of patients. Significant cancer was defined using varying thresholds of MCL or Gleason grade 3+4 or greater or both. Cancers with more than 80% of positive core length anterior to the level of urethra were termed anterior zone cancer. Secondary objective was to evaluate the potential clinical and radiological predictors for significant cancer detection. RESULTS: The mean age was 61.6 ± 6.5 years and median prostate-specific antigen was 10.4 ng/dl (7.9-18) with a mean MRI target size of 7.2mm (4-11). Transperineal template-guided mapping biopsy identified cancer in 36% (27/75) patients and 66.6% (18/27) of them were anterior zone cancers. The rates of detection of clinically significant and insignificant cancer according to the several definitions used range from 22.7% to 30.7% and 5.3% to 13.3%, respectively. Multivariate analysis did not identify any predictors for finding clinically significant and anterior cancers in this group of patients. CONCLUSION: Transperineal template-guided mapping biopsy appears to be an excellent biopsy protocol for downstream management following negative MRI-guided biopsy. Most of the cancers detected were predominantly anterior tumors.

JOURNAL ARTICLE

Valerio M, Ahmed HU, Emberton M, 2015, Focal Therapy of Prostate Cancer Using Irreversible Electroporation, TECHNIQUES IN VASCULAR AND INTERVENTIONAL RADIOLOGY, Vol: 18, Pages: 147-152, ISSN: 1089-2516

JOURNAL ARTICLE

Valerio M, Anele C, Freeman A, Jameson C, Singh PB, Hu Y, Emberton M, Ahmed HUet al., 2015, Identifying the Index Lesion with Template Prostate Mapping Biopsies, JOURNAL OF UROLOGY, Vol: 193, Pages: 1185-1190, ISSN: 0022-5347

JOURNAL ARTICLE

Valerio M, Donaldson I, Emberton M, Ehdaie B, Hadaschik BA, Marks LS, Mozer P, Rastinehad AR, Ahmed HUet al., 2015, Detection of Clinically Significant Prostate Cancer Using Magnetic Resonance Imaging-Ultrasound Fusion Targeted Biopsy: A Systematic Review, EUROPEAN UROLOGY, Vol: 68, Pages: 8-19, ISSN: 0302-2838

JOURNAL ARTICLE

Valerio M, McCartan N, Freeman A, Punwani S, Emberton M, Ahmed HUet al., 2015, Visually directed vs. software-based targeted biopsy compared to transperineal template mapping biopsy in the detection of clinically significant prostate cancer, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, Vol: 33, ISSN: 1078-1439

JOURNAL ARTICLE

Valerio M, Willis S, van der Meulen J, Emberton M, Ahmed HUet al., 2015, Methodological considerations in assessing the utility of imaging in early prostate cancer, CURRENT OPINION IN UROLOGY, Vol: 25, Pages: 536-542, ISSN: 0963-0643

JOURNAL ARTICLE

Willis SR, van der Meulen J, Valerio M, Miners A, Ahmed HU, Emberton Met al., 2015, A review of economic evaluations of diagnostic strategies using imaging in men at risk of prostate cancer, CURRENT OPINION IN UROLOGY, Vol: 25, Pages: 483-489, ISSN: 0963-0643

JOURNAL ARTICLE

Abd-Alazeez M, Ahmed HU, Arya M, Allen C, Dikaios N, Freeman A, Emberton M, Kirkham Aet al., 2014, Can multiparametric magnetic resonance imaging predict upgrading of transrectal ultrasound biopsy results at more definitive histology?, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, Vol: 32, Pages: 741-747, ISSN: 1078-1439

JOURNAL ARTICLE

Abd-Alazeez M, Ahmed HU, Arya M, Charman SC, Anastasiadis E, Freeman A, Emberton M, Kirkham Aet al., 2014, The accuracy of multiparametric MRI in men with negative biopsy and elevated PSA level-Can it rule out clinically significant prostate cancer?, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, Vol: 32, ISSN: 1078-1439

JOURNAL ARTICLE

Abd-Alazeez M, Kirkham A, Ahmed HU, Arya M, Anastasiadis E, Charman SC, Freeman A, Emberton Met al., 2014, Performance of multiparametric MRI in men at risk of prostate cancer before the first biopsy: a paired validating cohort study using template prostate mapping biopsies as the reference standard, PROSTATE CANCER AND PROSTATIC DISEASES, Vol: 17, Pages: 40-46, ISSN: 1365-7852

JOURNAL ARTICLE

Ahmed HU, 2014, PROSTATE CANCER Melbourne Consensus-noble but misguided, NATURE REVIEWS UROLOGY, Vol: 11, Pages: 250-251, ISSN: 1759-4812

JOURNAL ARTICLE

Ahmed HU, 2014, Introduction-Targeting the lesion, not the organ, UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, Vol: 32, Pages: 901-902, ISSN: 1078-1439

JOURNAL ARTICLE

Ahmed HU, Berge V, Bottomley D, Cross W, Heer R, Kaplan R, Leslie T, Parker C, Relton C, Stephens R, Sydes MR, Turnbull L, van der Meulen J, Vickers A, Wilt T, Emberton Met al., 2014, Can we deliver randomized trials of focal therapy in prostate cancer?, NATURE REVIEWS CLINICAL ONCOLOGY, Vol: 11, Pages: 482-491, ISSN: 1759-4774

JOURNAL ARTICLE

Berge V, Dickinson L, McCartan N, Hindley RG, Diep LM, Emberton M, Ahmed HUet al., 2014, Morbidity Associated with Primary High Intensity Focused Ultrasound and Redo High Intensity Focused Ultrasound for Localized Prostate Cancer, JOURNAL OF UROLOGY, Vol: 191, Pages: 1764-1769, ISSN: 0022-5347

JOURNAL ARTICLE

Gómez-Veiga F, Martínez-Breijo S, Solsona-Narbón E, Hernández C, Ciudin A, Ribal MJ, Dickinson L, Moore C, Ahmed H, Rodríguez Antolín A, Breda A, Gaya J, Portela-Pereira P, Emberton Met al., 2014, Focal therapy for prostate cancer. Alternative treatment., Actas Urol Esp, Vol: 38, Pages: 465-475

CONTEXT: The great controversy surrounding the treatment of localized prostate cancer is related with its possibilities of radical treatment or active surveillance. The objective of this paper is to analyze the rationale selection among current focal therapy modalities regarding tumor and patient selection. EVIDENCE ACQUISITION: Current articles about advantages and disadvantages on the treatment of localized prostate cancer as well as information about focal therapy regarding tumour selection, characteristics and indications cited in MEDLINE search were reviewed. SUMMARY OF EVIDENCE: Focal therapy standardized criteria must be: low risk tumors, PSA<10-15, Gleason score ≤ 6, and unilateral presentation all supported by image-guided biopsy and nuclear magnetic resonance (NMR). There are doubts about the suitability of focal therapy in cases of bilateralism or in those with Gleason score 3+4 or PSA>15. CONCLUSIONS: Focal therapy is an alternative for localized prostate cancer treatment. However, some aspects of their diagnosis and selection criteria should be defined by prospective studies which should provide knowledge about the indication for focal therapy.

JOURNAL ARTICLE

Gómez-Veiga F, Portela-Pereira P, Cozar-Olmo JM, Ahmed H, Moore C, Dickinson L, Algaba F, Izquierdo L, Alcaraz Asensio A, Martinez-Breijo S, Emberton Met al., 2014, Focal therapy for prostate cancer. Rationale, indications and selection., Actas Urol Esp, Vol: 38, Pages: 405-412

CONTEXT: The great controversy surrounding the treatment of localized prostate cancer is related with its possibilities of radical treatment or active surveillance. The objective of this paper is to analyze the rationale selection among current focal therapy modalities regarding tumor and patient selection. EVIDENCE ACQUISITION: Current articles about advantages and disadvantages on the treatment of localized prostate cancer as well as information about focal therapy regarding tumour selection, characteristics and indications cited in MEDLINE search were reviewed. SUMMARY OF EVIDENCE: Focal therapy standardized criteria must be: low risk tumors, PSA<10-15, Gleason score ≤ 6, and unilateral presentation all supported by image-guided biopsy and nuclear magnetic resonance (NMR). There are doubts about the suitability of focal therapy in cases of bilateralism or in those with Gleason score 3+4 or PSA>15. CONCLUSIONS: Focal therapy is an alternative for localized prostate cancer treatment. However, some aspects of their diagnosis and selection criteria should be defined by prospective studies which should provide knowledge about the indication for focal therapy.

JOURNAL ARTICLE

Kanthabalan A, Emberton M, Ahmed HU, 2014, Biopsy strategies for selecting patients for focal therapy for prostate cancer, CURRENT OPINION IN UROLOGY, Vol: 24, Pages: 209-217, ISSN: 0963-0643

JOURNAL ARTICLE

Lee DJ, Ahmed HU, Moore CM, Emberton M, Ehdaie Bet al., 2014, Multiparametric Magnetic Resonance Imaging in the Management and Diagnosis of Prostate Cancer: Current Applications and Strategies, CURRENT UROLOGY REPORTS, Vol: 15, ISSN: 1527-2737

JOURNAL ARTICLE

Robertson NL, Hu Y, Ahmed HU, Freeman A, Barratt D, Emberton Met al., 2014, Prostate Cancer Risk Inflation as a Consequence of Image-targeted Biopsy of the Prostate: A Computer Simulation Study, EUROPEAN UROLOGY, Vol: 65, Pages: 628-634, ISSN: 0302-2838

JOURNAL ARTICLE

Shah TT, Ahmed H, Kanthabalan A, Lau B, Ghei M, Maraj B, Arya Met al., 2014, Focal cryotherapy of localized prostate cancer: a systematic review of the literature, EXPERT REVIEW OF ANTICANCER THERAPY, Vol: 14, Pages: 1337-1347, ISSN: 1473-7140

JOURNAL ARTICLE

Simmons LAM, Ahmed HU, Moore CM, Punwani S, Freeman A, Hu Y, Barratt D, Charman SC, Van der Meulen J, Emberton Met al., 2014, The PICTURE study - Prostate Imaging (multi-parametric MRI and Prostate HistoScanning (TM)) Compared to Transperineal Ultrasound guided biopsy for significant prostate cancer Risk Evaluation, CONTEMPORARY CLINICAL TRIALS, Vol: 37, Pages: 69-83, ISSN: 1551-7144

JOURNAL ARTICLE

Singh PB, Anele C, Dalton E, Barbouti O, Stevens D, Gurung P, Arya M, Jameson C, Freeman A, Emberton M, Ahmed HUet al., 2014, Prostate Cancer Tumour Features on Template Prostate-mapping Biopsies: Implications for Focal Therapy, EUROPEAN UROLOGY, Vol: 66, Pages: 12-19, ISSN: 0302-2838

JOURNAL ARTICLE

Valerio M, Ahmed HU, 2014, Re: Tumor Target Volume for Focal Therapy of Prostate Cancerd-Does Multiparametric Magnetic Resonance Imaging Allow for a Reliable Estimation?, JOURNAL OF UROLOGY, Vol: 192, Pages: 1297-1298, ISSN: 0022-5347

JOURNAL ARTICLE

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