Imperial College London

Professor Hashim Ahmed

Faculty of MedicineDepartment of Surgery & Cancer

Chair in Urology (Clinical)
 
 
 
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Contact

 

hashim.ahmed

 
 
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Location

 

5L28Lab BlockCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

275 results found

Kasivisvanathan V, Dufour R, Moore CM, Ahmed HU, Abd-Alazeez M, Charman SC, Freeman A, Allen C, Kirkham A, van der Meulen J, Emberton Met al., 2013, Multiparametric MRI in the diagnosis of prostate cancer: a validation study of the European Consensus Meeting Risk Scoring System, Annual Scientific Meeting of the British-Association-of-Urological-Surgeons (BAUS), Publisher: WILEY-BLACKWELL, Pages: 11-11, ISSN: 1464-4096

CONFERENCE PAPER

Kasivisvanathan V, Emberton M, Ahmed HU, 2013, Focal Therapy for Prostate Cancer: Rationale and Treatment Opportunities, CLINICAL ONCOLOGY, Vol: 25, Pages: 461-473, ISSN: 0936-6555

JOURNAL ARTICLE

Loeb S, Vellekoop A, Ahmed HU, Catto J, Emberton M, Nam R, Rosario DJ, Scattoni V, Lotan Yet al., 2013, Systematic Review of Complications of Prostate Biopsy, EUROPEAN UROLOGY, Vol: 64, Pages: 876-892, ISSN: 0302-2838

JOURNAL ARTICLE

Simmons L, Ahmed HU, Winkler M, Zatura F, Braeckman J, Autier PA, Nir D, Meiers I, Charman S, Emberton Met al., 2013, PROSTATE HISTOSCANNING FOR THE DETECTION OF CLINICALLY SIGNIFICANT PROSTATE CANCER - RESULTS FROM THE BLIND PHASE OF THE MULTICENTRE EUROPEAN PHS02 STUDY, Annual Meeting of the American-Urological-Association (AUA), Publisher: ELSEVIER SCIENCE INC, Pages: E907-E908, ISSN: 0022-5347

CONFERENCE PAPER

Wilt TJ, Ahmed HU, 2013, Prostate cancer screening and the management of clinically localized disease, BMJ-BRITISH MEDICAL JOURNAL, Vol: 346, ISSN: 1756-1833

JOURNAL ARTICLE

Abd Alazeez M, Ahmed H, Moore C, Kirkham A, Freeman A, Emberton Met al., 2012, The Role of mp-MRI in the Detection of Prostate Cancer, CLINICAL ONCOLOGY, Vol: 24, Pages: 154-154, ISSN: 0936-6555

JOURNAL ARTICLE

Abd Alazeez M, Ahmed HU, Anastasiadis E, Arya M, Kirkham A, Emberton Met al., 2012, Can multi-parametric MRI prior to first TRUS biopsy rule out clinically important prostate cancer? A validating cohort study using template prostate mapping as a reference test, Annual Scientific Meeting of the British-Association-of-Urological-Surgeons (BAUS), Publisher: WILEY-BLACKWELL, Pages: 17-17, ISSN: 1464-4096

CONFERENCE PAPER

Ahmed HU, 2012, Focal Therapy Will Become Standard Treatment for Localized Prostate Cancer, JOURNAL OF UROLOGY, Vol: 187, Pages: 792-794, ISSN: 0022-5347

JOURNAL ARTICLE

Ahmed HU, Akin O, Coleman JA, Crane S, Emberton M, Goldenberg L, Hricak H, Kattan MW, Kurhanewicz J, Moore CM, Parker C, Polascik TJ, Scardino P, van As N, Villers Aet al., 2012, Transatlantic Consensus Group on active surveillance and focal therapy for prostate cancer, BJU INTERNATIONAL, Vol: 109, Pages: 1636-1647, ISSN: 1464-4096

JOURNAL ARTICLE

Ahmed HU, Arumainayagam N, Kirkham AP, Allen C, Sohaib SA, Freeman A, Emberton Met al., 2012, What burden of prostate cancer can radiologists rule-out on multi-parametric MRI? An analysis based on template prostate mapping biopsies as the reference standard, EUROPEAN UROLOGY SUPPLEMENTS, Vol: 11, Pages: E795-U685, ISSN: 1569-9056

JOURNAL ARTICLE

Ahmed HU, Arya M, Freeman A, Emberton Met al., 2012, Do low-grade and low-volume prostate cancers bear the hallmarks of malignancy?, LANCET ONCOLOGY, Vol: 13, Pages: E509-E517, ISSN: 1470-2045

JOURNAL ARTICLE

Ahmed HU, Cathcart P, Chalasani V, Williams A, McCartan N, Freeman A, Kirkham A, Allen C, Chin J, Emberton Met al., 2012, Whole-gland salvage high-intensity focused ultrasound therapy for localized prostate cancer recurrence after external beam radiation therapy, CANCER, Vol: 118, Pages: 3071-3078, ISSN: 0008-543X

JOURNAL ARTICLE

Ahmed HU, Cathcart P, McCartan N, Kirkham A, Allen C, Freeman A, Emberton Met al., 2012, Focal salvage therapy for localized prostate cancer recurrence after external beam radiotherapy A Pilot Study, CANCER, Vol: 118, Pages: 4148-4155, ISSN: 0008-543X

JOURNAL ARTICLE

Ahmed HU, Emberton M, 2012, URINARY INCONTINENCE AFTER PROSTATE CANCER Image guided diagnosis and treatment to prevent incontinence after radical prostatectomy, BRITISH MEDICAL JOURNAL, Vol: 344, ISSN: 0959-535X

JOURNAL ARTICLE

Ahmed HU, Emberton M, 2012, Focal HIFU for prostate cancer Reply, LANCET ONCOLOGY, Vol: 13, Pages: E284-E284, ISSN: 1470-2045

JOURNAL ARTICLE

Ahmed HU, Emberton M, Kepner G, Kepner Jet al., 2012, A biomedical engineering approach to mitigate the errors of prostate biopsy, NATURE REVIEWS UROLOGY, Vol: 9, Pages: 227-U81, ISSN: 1759-4812

JOURNAL ARTICLE

Ahmed HU, Gabe R, Kaplan R, Parker C, Emberton Met al., 2012, Multi-parametric magnetic resonance imaging in the diagnosis and characterization of prostate cancer prior to first biopsy in men at risk: The PROMIS study, EUROPEAN UROLOGY SUPPLEMENTS, Vol: 11, Pages: E824-U743, ISSN: 1569-9056

JOURNAL ARTICLE

Ahmed HU, Hindley RG, Dickinson L, Freeman A, Kirkham AP, Sahu M, Scott R, Allen C, Van der Meulen J, Emberton Met al., 2012, Focal therapy for localised unifocal and multifocal prostate cancer: a prospective development study, LANCET ONCOLOGY, Vol: 13, Pages: 622-632, ISSN: 1470-2045

JOURNAL ARTICLE

Ahmed HU, Singh P, Dalton E, Stevens D, Barbouti O, Gurung P, Freeman A, Emberton Met al., 2012, Patterns of prostate cancer on template prostate mapping biopsies in 291 men: Implications for focal therapy, EUROPEAN UROLOGY SUPPLEMENTS, Vol: 11, Pages: E22-U334, ISSN: 1569-9056

JOURNAL ARTICLE

Barzell WE, Melamed MR, Cathcart P, Moore CM, Ahmed HU, Emberton Met al., 2012, Identifying Candidates for Active Surveillance: An Evaluation of the Repeat Biopsy Strategy for Men with Favorable Risk Prostate Cancer, JOURNAL OF UROLOGY, Vol: 188, Pages: 762-767, ISSN: 0022-5347

JOURNAL ARTICLE

Dickinson L, Ahmed H, McCartan N, Freeman A, Kirkham A, Allen C, Hindley R, Emberton Met al., 2012, Medium-Term Outcomes Following Primary Focal Therapy Using HIFU for Localized Prostate Cancer, UROLOGY, Vol: 80, Pages: S162-S162, ISSN: 0090-4295

JOURNAL ARTICLE

Dickinson L, Hu Y, Ahmed H, Allen C, Kirkham A, Emberton M, Barratt Det al., 2012, MRI-Guided Prostate Cancer Focal Ablation Using HIFU by Means of Image to Image Registration, UROLOGY, Vol: 80, Pages: S161-S161, ISSN: 0090-4295

JOURNAL ARTICLE

Dickinson L, Hu Y, Carter T, Ahmed HU, Allen C, Kirkham A, Emberton M, Barratt Det al., 2012, MR-directed selective HIFU therapy of prostate cancer using a TRUS guidance platform, EUROPEAN UROLOGY SUPPLEMENTS, Vol: 11, Pages: E24-U338, ISSN: 1569-9056

JOURNAL ARTICLE

Hu Y, Ahmed HU, Carter T, Arumainayagam N, Lecornet E, Barzell W, Freeman A, Nevoux P, Hawkes DJ, Villers A, Emberton M, Barratt DCet al., 2012, A biopsy simulation study to assess the accuracy of several transrectal ultrasonography (TRUS)-biopsy strategies compared with template prostate mapping biopsies in patients who have undergone radical prostatectomy, BJU INTERNATIONAL, Vol: 110, Pages: 812-820, ISSN: 1464-4096

JOURNAL ARTICLE

Hu Y, Ahmed HU, Taylor Z, Allen C, Emberton M, Hawkes D, Barratt Det al., 2012, MR to ultrasound registration for image-guided prostate interventions, MEDICAL IMAGE ANALYSIS, Vol: 16, Pages: 687-703, ISSN: 1361-8415

JOURNAL ARTICLE

Karavitakis M, Ahmed HU, Abel PD, Hazell S, Winkler MHet al., 2012, Margin Status After Laparoscopic Radical Prostatectomy and the Index Lesion: Implications for Preoperative Evaluation of Tumor Focality in Prostate Cancer, JOURNAL OF ENDOUROLOGY, Vol: 26, Pages: 503-508, ISSN: 0892-7790

JOURNAL ARTICLE

Karavitakis M, Ahmed HU, Abel PD, Hazell S, Winkler MHet al., 2012, Anatomically versus biologically unifocal prostate cancer: a pathological evaluation in the context of focal therapy., Ther Adv Urol, Vol: 4, Pages: 155-160

OBJECTIVES: Since tumor focality in prostate cancer continues to be considered a major limitation for focal prostate therapy, in this study we attempted to compare the pathological features and the proportion of patients with anatomically unifocal versus biologically unifocal tumors (i.e. multifocal prostate cancer in which the secondary nonindex elements are small, low grade and clinically insignificant) who were suitable for focal therapy. METHODS: Ninety-five consecutive whole mount laparoscopic radical prostatectomy samples underwent pathological assessment (from January 2007 to November 2009). Tumor focality, laterality, Gleason score and volume of individual foci, total tumor volume, pathological stage and surgical margin status were assessed. The index lesion was defined as the largest by volume. Patients suitable for focal ablation were defined as having tumors that were unifocal, organ confined, with a Gleason score (GS) up to 7 prostate cancer, or multifocal, organ confined, GS up to 7 prostate cancer, with one large index lesion and the remaining foci demonstrating features of clinically insignificant disease (total tumor volume of all secondary foci ≤0.5 cm(3) with GS ≤ 6). RESULTS: Patients with biologically unifocal cancer had significantly lower total tumor volume (3.26 versus 7.28 cm(3); p < 0.001), index lesion volume (2.9 versus 7.16 cm(3); p < 0.001), rates of seminal vesicle invasion (4% versus 34%; p < 0.001), rates of positive surgical margins (22.4% versus 52.1%; p < 0.001) and rates of 4+3 GS tumors (10.2% versus 29.1%; p = 0.018). The proportion of patients suitable for focal therapy was higher in the biologically unifocal versus anatomically unifocal cancer group, although without reaching statistical significance (65.3% versus 45.8%; p = 0.11). CONCLUSIONS: Patients with biologically unifocal tumors have better pathological outcome than those with anatomically unifocal disease. At present the assumption that multifocality

JOURNAL ARTICLE

Karavitakis M, Ahmed HU, Abel PD, Livni N, Hazell S, Winkler MHet al., 2012, Trends in pathologic outcomes after introduction of active surveillance in the UK: Implication for focal therapy, PROSTATE, Vol: 72, Pages: 1464-1468, ISSN: 0270-4137

JOURNAL ARTICLE

Karavitakis M, Ahmed HU, Abel PD, Livni N, Hazell S, Winkler MHet al., 2012, Evolution of the pathological outcomes after radical prostatectomy with increasing use of active surveillance in the UK: Implication for focal therapy, EUROPEAN UROLOGY SUPPLEMENTS, Vol: 11, Pages: E20-U330, ISSN: 1569-9056

JOURNAL ARTICLE

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