Imperial College London
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Professor Hashim Ahmed

Faculty of Medicine, Department of Surgery & Cancer

Chair in Urology (Clinical)
 
 
 
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Contact

 

hashim.ahmed

 
 
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Location

 

5L28Lab BlockCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Afaq:2017:10.2967/jnumed.117.192625,
author = {Afaq, A and Alahmed, S and Chen, S-H and Lengana, T and Haroon, A and Payne, H and Ahmed, H and Punwani, S and Sathekge, M and Bomanji, J},
doi = {10.2967/jnumed.117.192625},
journal = {Journal of Nuclear Medicine},
title = {(68)Ga-PSMA PET/CT impact on prostate cancer management.},
url = {http://dx.doi.org/10.2967/jnumed.117.192625},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Aim: To assess the impact of (68)Ga-Prostate Specific Membrane Antigen (PSMA) Positron Emission Tomography/ Computed Tomography (PET/CT) on management of prostate cancer in patients with biochemical recurrence (BCR). Methods: Documented management plans were retrospectively reviewed before and after (68)Ga-PSMA PET/CT in 100 patients with BCR and change in plans recorded. Results: Management changed after (68)Ga-PSMA PET/CT in 39 patients (39%). These occurred in 23/68 (33.8%) of patients with radical prostatectomy (RP) and 16/32 (50%) of patients previously treated with radical radiotherapy. Positive scan (P < 0.001) and higher Prostate Specific Antigen (PSA) (P = 0.024) were associated with management changes. No significant association with management change was found with Gleason grade, stage, presence of metastatic disease, PSA velocity or doubling time. Conclusion:(68)Ga-PSMA PET/CT altered management in 39% of patients with BCR, and occurred more often in patients with radical radiotherapy treatment, a positive (68)Ga-PSMA scan and higher PSA level.
AU  - Afaq,A
AU  - Alahmed,S
AU  - Chen,S-H
AU  - Lengana,T
AU  - Haroon,A
AU  - Payne,H
AU  - Ahmed,H
AU  - Punwani,S
AU  - Sathekge,M
AU  - Bomanji,J
DO  - 10.2967/jnumed.117.192625
PY  - 2017///
SN  - 1535-5667
TI  - (68)Ga-PSMA PET/CT impact on prostate cancer management.
T2  - Journal of Nuclear Medicine
UR  - http://dx.doi.org/10.2967/jnumed.117.192625
ER  -
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