Imperial College London
Portrait Picture

Professor Hashim Ahmed

Faculty of Medicine, Department of Surgery & Cancer

Chair in Urology (Clinical)
 
 
 
//

Contact

 

hashim.ahmed

 
 
//

Location

 

5L28Lab BlockCharing Cross Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Borghesi:2016:10.1016/j.eururo.2016.08.004,
author = {Borghesi, M and Ahmed, H and Nam, R and Schaeffer, E and Schiavina, R and Taneja, S and Weidner, W and Loeb, S},
doi = {10.1016/j.eururo.2016.08.004},
journal = {European Urology},
pages = {353--365},
title = {Complications after systematic, random, and image-guided prostate biopsy},
url = {http://dx.doi.org/10.1016/j.eururo.2016.08.004},
volume = {71},
year = {2016}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - ContextProstate biopsy (PB) represents the gold standard method to confirm the presence of cancer. In addition to traditional random or systematic approaches, a magnetic resonance imaging (MRI)–guided technique has been introduced recently.ObjectiveTo perform a systematic review of complications after transrectal ultrasound (TRUS)–guided, transperineal, and MRI-guided PB.Evidence acquisitionWe performed a systematic literature search of Web of Science, Embase, and Scopus databases up to October 2015, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Complications and mortality following random, systematic, and image-guided PBs were reviewed. Eighty-five references were included.Evidence synthesisThe most frequent complication after PB was minor and self-limiting bleeding (hematuria and hematospermia), regardless of the biopsy approach. Occurrence of rectal bleeding was comparable for traditional TRUS-guided and image-guided PBs. Almost 25% of patients experienced lower urinary tract symptoms, but only a few had urinary retention, with higher rates after a transperineal approach. Temporary erectile dysfunction was not negligible, with a return to baseline after 1–6 mo. The incidence of infective complications is increasing, with higher rates among men with medical comorbidities and older age. Transperineal and in-bore MRI–targeted biopsy may reduce the risk of severe infectious complications. Mortality after PB is uncommon, regardless of biopsy technique.ConclusionsComplications after PB are frequent but often self-limiting. The incidence of hospitalization due to severe infections is continuously increasing. The patient's general health status, risk factors, and likelihood of antimicrobial resistance should be carefully appraised before scheduling a PB.
AU  - Borghesi,M
AU  - Ahmed,H
AU  - Nam,R
AU  - Schaeffer,E
AU  - Schiavina,R
AU  - Taneja,S
AU  - Weidner,W
AU  - Loeb,S
DO  - 10.1016/j.eururo.2016.08.004
EP  - 365
PY  - 2016///
SN  - 0302-2838
SP  - 353
TI  - Complications after systematic, random, and image-guided prostate biopsy
T2  - European Urology
UR  - http://dx.doi.org/10.1016/j.eururo.2016.08.004
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396333700015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - http://hdl.handle.net/10044/1/53868
VL  - 71
ER  -
Download