Imperial College London

DrIanMaconochie

Faculty of MedicineSchool of Public Health

Professor of Practice (Paediatric Emergency Medicine)
 
 
 
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Contact

 

+44 (0)20 3312 3729i.maconochie

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Publication Type
Year
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249 results found

Maconochie IK, Bingham R, 2014, ABC of Resuscitation, 6th Edition Paediatric Resuscitation, BMJ-BRITISH MEDICAL JOURNAL, Vol: 348, ISSN: 1756-1833

Journal article

Hartshorn S, Bevan C, Cleugh F, Lyttle M, Maconochie I, O'Sullivan Ret al., 2014, G12 What are the Research Priorities of Paediatric Emergency Medicine Clinicians in the United Kingdom & Ireland? An International Survey, Archives of Disease in Childhood, Vol: 99, Pages: A5-A6, ISSN: 0003-9888

Journal article

Mintegi S, Lyttle MD, Maconochie IK, Benito J, Gervaix A, Moll H, Shavit I, Da Dalt L, Waisman Yet al., 2014, From cradle to adolescence: the development of Research in European Pediatric Emergency Medicine, EUROPEAN JOURNAL OF EMERGENCY MEDICINE, Vol: 21, Pages: 24-29, ISSN: 0969-9546

Journal article

Seiger N, van Veen M, Almeida H, Steyerberg EW, van Meurs AHJ, Carneiro R, Alves CF, Maconochie I, van der Lei J, Moll HAet al., 2014, Improving the manchester triage system for pediatric emergency care: an international multicenter study, PLOS One, Vol: 9, ISSN: 1932-6203

ObjectivesThis multicenter study examines the performance of the Manchester Triage System (MTS) after changing discriminators, and with the addition use of abnormal vital sign in patients presenting to pediatric emergency departments (EDs).DesignInternational multicenter studySettingsEDs of two hospitals in The Netherlands (2006–2009), one in Portugal (November–December 2010), and one in UK (June–November 2010).PatientsChildren (<16years) triaged with the MTS who presented at the ED.MethodsChanges to discriminators (MTS 1) and the value of including abnormal vital signs (MTS 2) were studied to test if this would decrease the number of incorrect assignment. Admission to hospital using the new MTS was compared with those in the original MTS. Likelihood ratios, diagnostic odds ratios (DORs), and c-statistics were calculated as measures for performance and compared with the original MTS. To calculate likelihood ratios and DORs, the MTS had to be dichotomized in low urgent and high urgent.Results60,375 patients were included, of whom 13% were admitted. When MTS 1 was used, admission to hospital increased from 25% to 29% for MTS ‘very urgent’ patients and remained similar in lower MTS urgency levels. The diagnostic odds ratio improved from 4.8 (95%CI 4.5–5.1) to 6.2 (95%CI 5.9–6.6) and the c-statistic remained 0.74. MTS 2 did not improve the performance of the MTS.ConclusionsMTS 1 performed slightly better than the original MTS. The use of vital signs (MTS 2) did not improve the MTS performance.

Journal article

Maconochie IK, Bhaumik S, 2014, Fluid therapy for acute bacterial meningitis, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

Journal article

Plunkett A, Maconochie I, Scholefield BR, 2014, Towards global reporting of every paediatric cardiac arrest, RESUSCITATION, Vol: 85, Pages: 15-16, ISSN: 0300-9572

Journal article

Seiger N, Maconochie I, Oostenbrink R, Moll HAet al., 2013, Validity of Different Pediatric Early Warning Scores in the Emergency Department, PEDIATRICS, Vol: 132, Pages: E841-E850, ISSN: 0031-4005

Journal article

Cheung R, Ardolino A, Lawrence T, Bouamra O, Lecky FE, Berry K, Chaudhury A, Issa S, Koralage N, Lyttle MD, Maconochie IKet al., 2013, THE ACCURACY OF EXISTING PRE-HOSPITAL TRIAGE TOOLS FOR INJURED CHILDREN IN ENGLAND–AN ANALYSIS USING TRAUMA REGISTRY AND EMERGENCY DEPARTMENT DATA, Emergency Medicine Journal, Vol: 30, Pages: 867.1-867, ISSN: 1472-0205

Journal article

Lyttle MD, Ardolino A, Berry K, Bouamra O, Cheung R, Lawrence T, Lecky F, Maconochie IKet al., 2013, USING EXISTING PAEDIATRIC PRE-HOSPITAL TRAUMA TRIAGE TOOLS TO IDENTIFY CHILDREN WITH SEVERE TRAUMATIC BRAIN INJURY–AN ANALYSIS OF NATIONAL TRAUMA REGISTRY DATA, Emergency Medicine Journal, Vol: 30, Pages: 879.2-879, ISSN: 1472-0205

Journal article

Maconochie I, Bingham R, 2013, How to perform cardiopulmonary resuscitation: an opportunity for technology development, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 98, Pages: 571-572, ISSN: 0003-9888

Journal article

Martin P, Theobald P, Kemp A, Maguire S, Maconochie I, Jones Met al., 2013, Real-time feedback can improve infant manikin cardiopulmonary resuscitation by up to 79%-A randomised controlled trial, RESUSCITATION, Vol: 84, Pages: 1125-1130, ISSN: 0300-9572

Journal article

Martin P, Theobald P, Kemp A, Maguire S, Maconochie I, Jones Met al., 2013, P11 Can Real-Time Performance Feedback Improve Chest Compression Quality During Simulated Infant CPR? A Randomised Controlled Trial, Archives of Disease in Childhood, Vol: 98, Pages: A5-A6, ISSN: 0003-9888

Journal article

Cheung R, Ardolino A, Lawrence T, Bouamra O, Lecky F, Berry K, Lyttle MD, Maconochie IKet al., 2013, The accuracy of existing prehospital triage tools for injured children in England-an analysis using trauma registry data, EMERGENCY MEDICINE JOURNAL, Vol: 30, Pages: 476-479, ISSN: 1472-0205

Journal article

Van de Voorde P, Emerson B, Gomez B, Willems J, Yildizdas D, Iglowstein I, Kerkhof E, Mullen N, Pinto CR, Detaille T, Qureshi N, Naud J, De Dooy J, Van Lancker R, Dupont A, Boelsma N, Mor M, Walker D, Sabbe M, Hachimi-Idrissi S, Da Dalt L, Waisman H, Biarent D, Maconochie I, Moll H, Benito Jet al., 2013, Paediatric community-acquired septic shock: results from the REPEM network study, EUROPEAN JOURNAL OF PEDIATRICS, Vol: 172, Pages: 667-674, ISSN: 0340-6199

Introduction and purpose of the studyWith this study we aimed to describe a “true world” picture of severe paediatric ‘community-acquired’ septic shock and establish the feasibility of a future prospective trial on early goal-directed therapy in children. During a 6-month to 1-year retrospective screening period in 16 emergency departments (ED) in 12 different countries, all children with severe sepsis and signs of decreased perfusion were included.ResultsA 270,461 paediatric ED consultations were screened, and 176 cases were identified. Significant comorbidity was present in 35.8 % of these cases. Intensive care admission was deemed necessary in 65.7 %, mechanical ventilation in 25.9 % and vasoactive medications in 42.9 %. The median amount of fluid given in the first 6 h was 30 ml/kg. The overall mortality in this sample was 4.5 %. Only 1.2 % of the survivors showed a substantial decrease in Paediatric Overall Performance Category (POPC). ‘Severe’ outcome (death or a decrease ≥2 in POPC) was significantly related (p < 0.01) to: any desaturation below 90 %, the amount of fluid given in the first 6 h, the need for and length of mechanical ventilation or vasoactive support, the use of dobutamine and a higher lactate or lower base excess but not to any variables of predisposition, infection or host response (as in the PIRO (Predisposition, Infection, Response, Organ dysfunction) concept).ConclusionThe outcome in our sample was very good. Many children received treatment early in their disease course, so avoiding subsequent intensive care. While certain variables predispose children to become septic and shocked, in our sample, only measures of organ dysfunction and concomitant treatment proved to be significantly related with outcome. We argue why future studies should rather be large multinational prospective observational trials and not necessarily randomised controlled trials.

Journal article

Cleugh FM, Maconochie IK, 2013, Management of the multiply injured child, Paediatrics and Child Health (United Kingdom), Vol: 23, Pages: 194-199, ISSN: 1751-7222

Injury is the commonest cause of death and morbidity in children and accounts for most attendances at paediatric emergency departments. However, the incidence of major trauma in UK children remains low. Optimal management of the multiply injured child relies on anticipation and preparation, followed by a standardized, consistent and structured response from healthcare professionals. Initial management involves a primary survey with resuscitation, using an 'ABC' approach, and treatment of life-threatening injuries as they arise. The details of this are outlined in this review, highlighting important child-specific factors. Once stabilized, injured children must be assessed by secondary survey to rule out all possible injuries and, if necessary, transferred to an appropriate tertiary unit. Support from regionalized trauma networks and ongoing training for staff is paramount in optimizing outcome of the multiply injured child. © 2012 Elsevier Ltd.

Journal article

Perkins GD, Bossaert L, Nolan J, Koster RW, Monsieurs K, Castren Met al., 2013, Proposed revisions to the EU clinical trials directive-Comments from the European Resuscitation Council, RESUSCITATION, Vol: 84, Pages: 263-264, ISSN: 0300-9572

Journal article

Wong T, Stang AS, Ganshorn H, Hartling L, Maconochie IK, Thomsen AM, Johnson DWet al., 2013, Combined and alternating paracetamol and ibuprofen therapy for febrile children, COCHRANE DATABASE OF SYSTEMATIC REVIEWS, ISSN: 1469-493X

Journal article

Maconochie I, 2013, Highlights from this issue, Emergency Medicine Journal, Vol: 30, Pages: 1-1, ISSN: 1472-0205

Journal article

Seiger N, Veen MV, Steyerberg E, Lei JVD, Ruige M, Meurs AV, Maconochie I, Moll Het al., 2012, 1621 Heart Rates and Respiratory Rates are Associated with Manchester Pain Scores in Children Presented at the Emergency Department, Archives of Disease in Childhood, Vol: 97, Pages: A459-A459, ISSN: 0003-9888

Journal article

Maconochie IK, 2012, Highlights from this issue, Emergency Medicine Journal, Vol: 29, Pages: 691-691, ISSN: 1472-0205

Journal article

Wright K, Oyeyinka K, Gilmour I, Salter R, Maconochie Iet al., 2012, Alcohol, violence and substance related presentations to A&E in 16-18 year olds: the need for targeted adolescent services, Archives of Disease in Childhood, Vol: 97, Pages: A150.1-A150, ISSN: 0003-9888

Journal article

Smith SA, Long CN, Denney G, Gray J, Lakhanpaul M, Maconochie I, Oates L, Rashid A, Slater Ret al., 2012, Care of children and young people with a decreased conscious level (multi-site audit 2010-2011), Archives of Disease in Childhood, Vol: 97, Pages: A143.3-A144, ISSN: 0003-9888

Journal article

Carasco C, Fletcher P, Maconochie I, 2012, Review of commonly used age based weight estimates for paediatric drug dosing in relation to the pharmacokinetic properties of resuscitation drugs, Archives of Disease in Childhood, Vol: 97, Pages: A147.2-A149, ISSN: 0003-9888

Journal article

Hann G, Moin Y, Kamal A, Maconochie Iet al., 2012, Towards the safer transfer of children during winter bed crises: a survey of London paediatric registrars' opinions on current transfer arrangements in order to improve patient safety, Archives of Disease in Childhood, Vol: 97, Pages: A144.1-A144, ISSN: 0003-9888

Journal article

Jain T, Long C, Rashid A, Denney G, Maconochie I, Grey J, Oates L, Lakhanpaul M, Salter R, Smith Set al., 2012, The impact of alcohol on conscious level in children and young people, Archives of Disease in Childhood, Vol: 97, Pages: A61.1-A61, ISSN: 0003-9888

Journal article

Farber HJ, Abramson SL, 2012, Highlights from this Issue, PEDIATRIC ALLERGY IMMUNOLOGY AND PULMONOLOGY, Vol: 25, Pages: 1-2, ISSN: 2151-321X

Journal article

Wong T, Johnson DW, Ganshorn H, Maconochie IK, Hartling L, Stang ASet al., 2012, Combined and alternating paracetamol and ibuprofen therapy for fever in children

Journal article

Maconochie IK, 2012, Highlights from this issue, Emergency Medicine Journal, Vol: 29, Pages: 1-1, ISSN: 1472-0205

Journal article

Clark A, Lloyd K, Sheikh A, Alfaham M, East M, Ewan P, Jewkes F, King R, Leech S, Maconochie I, Sinnott L, Sohi D, Tomlin S, Warner Jet al., 2011, The RCPCH care pathway for children at risk of anaphylaxis: an evidence and consensus based national approach to caring for children with life-threatening allergies, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 96, Pages: I6-I9, ISSN: 0003-9888

Journal article

Maguire S, Ranmal R, Komulainen S, Pearse S, Maconochie I, Lakhanpaul M, Davies F, Kai J, Stephenson Tet al., 2011, Which urgent care services do febrile children use and why?, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 96, Pages: 810-816, ISSN: 0003-9888

Journal article

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