Imperial College London

ProfessorIanWilson

Faculty of MedicineDepartment of Surgery & Cancer

Chair in Drug Metabolism and Molecular Toxicology
 
 
 
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Contact

 

+44 (0)20 7594 0730i.wilson

 
 
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Location

 

Room 102Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

Prof. Wilson holds the Chair in Drug Metabolism and Molecular Toxicology.

Ian Wilson trained as a biochemist at the University of Manchester Institute of Science and Technology, going on to a PhD at Keele University on insect moulting hormones. After this he worked in the Pharmaceutical industry, most recently as a Senior Principal Scientist in the Dept of Drug Metabolism and Pharmacokinetics at the AstraZeneca Research site at Alderley Park in Cheshire (UK), joining Imperial College in 2012. He is the author, or co-author, of some 480 papers or reviews, and has received a number of awards in separation and analytical science from the Royal Society of Chemistry, including the Gold Medal of the Analytical Division (2005) and most recently the Knox Medal of the RSC Separation Science Group (2012). He received the Jubilee Medal of the Chromatographic Society in 1994 and gave the inaugural Desty Memorial lecture for Innovation in Separation Science in1996. His research is directed towards the development of hyphenated techniques in chromatography and their application to problems in drug metabolism, toxicology and metabonomics

Publications

Journals

Gray N, Zia R, King A, et al., High speed quantitative UPLC-MS analysis of multiple amines in human plasma and serum via pre-column derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate: Application to acetaminophen-induced liver failure, Analytical Chemistry, ISSN:1520-6882

Wilson ID, Nicholson JK, Plumb RS, Ion Mobility Spectrometry Combined With Ultra Performance Liquid Chromatography/Mass Spectrometry For Metabolic Phenotyping of Urine: Effects of Column Length, Gradient Duration and Ion Mobility Spectrometry on Metabolite Detection., Analytica Chimica Acta, ISSN:1873-4324

Akingbasote JA, Foster AJ, Jones HB, et al., 2017, Improved hepatic physiology in hepatic cytochrome P450 reductase null (HRN™) mice dosed orally with fenclozic acid, Toxicology Research, Vol:6, ISSN:2045-452X, Pages:81-88

Gray N, Zia R, King A, et al., 2017, High-Speed Quantitative UPLC-MS Analysis of Multiple Amines in Human Plasma and Serum via Precolumn Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate: Application to Acetaminophen-Induced Liver Failure, Analytical Chemistry, Vol:89, ISSN:0003-2700, Pages:2478-2487

P. Dickie A, Wilson CE, Schreiter K, et al., 2017, Lumiracoxib metabolism in male C57bl/6J mice: characterisation of novel in vivo metabolites, Xenobiotica, Vol:47, ISSN:0049-8254, Pages:538-546

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