Imperial College London


Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Visiting Professor



+44 (0)20 7594 0730i.wilson




102Sir Alexander Fleming BuildingSouth Kensington Campus





Prof. Wilson holds the Chair in Drug Metabolism and Molecular Toxicology.

Ian Wilson trained as a biochemist at the University of Manchester Institute of Science and Technology, going on to a PhD at Keele University on insect moulting hormones. After this he worked in the Pharmaceutical industry, most recently as a Senior Principal Scientist in the Dept of Drug Metabolism and Pharmacokinetics at the AstraZeneca Research site at Alderley Park in Cheshire (UK), joining Imperial College in 2012. He is the author, or co-author, of some 480 papers or reviews, and has received a number of awards in separation and analytical science from the Royal Society of Chemistry, including the Gold Medal of the Analytical Division (2005) and most recently the Knox Medal of the RSC Separation Science Group (2012). He received the Jubilee Medal of the Chromatographic Society in 1994 and gave the inaugural Desty Memorial lecture for Innovation in Separation Science in1996. His research is directed towards the development of hyphenated techniques in chromatography and their application to problems in drug metabolism, toxicology and metabonomics



Gray N, Gethings LA, Plumb RS, et al., 2020, UHPLC-MS-Based lipidomic and metabonomic investigation of the metabolic phenotypes of wild type and hepatic CYP reductase null (HRN) mice, Journal of Pharmaceutical and Biomedical Analysis, Vol:186, ISSN:0731-7085, Pages:1-9

Wilson I, Letertre M, Munjoma N, et al., A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats, Journal of Proteome Research, ISSN:1535-3893

Letertre M, Munjoma NC, Slade SE, et al., Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat, Chromatographia, ISSN:0009-5893

Wilson I, Dargue R, Zia R, et al., 2020, Metabolism and effects on endogenous metabolism of paracetamol (acetaminophen) in a porcine model of liver failure, Toxicological Sciences, Vol:175, ISSN:1096-0929, Pages:87-97

Dargue R, Grant I, Nye L, et al., 2020, The analysis of acetaminophen (paracetamol) and 7 metabolites in rat, pig and human plasma by U(H)PLC-MS, Bioanalysis, Vol:12, ISSN:1757-6180, Pages:485-500

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