Imperial College London

ProfessorJaneMitchell

Faculty of MedicineNational Heart & Lung Institute

Professor of Pharmacology in Critical Care Medicine
 
 
 
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Contact

 

+44 (0)20 7351 8137j.a.mitchell

 
 
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Assistant

 

Ms Lisa Quinn +44 (0)20 7594 1345

 
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Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Publication Type
Year
to

415 results found

Harrington LS, Mitchell JA, 2004, Novel role for P2X receptor activation in endothelium-dependent vasodilation, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 143, Pages: 611-617, ISSN: 0007-1188

Journal article

Osborne CS, Chakalova L, Brown KE, Carter D, Horton A, Debrand E, Goyenechea B, Mitchell JA, Lopes S, Reik W, Fraser Pet al., 2004, Active genes dynamically colocalize to shared sites of ongoing transcription, NATURE GENETICS, Vol: 36, Pages: 1065-1071, ISSN: 1061-4036

Journal article

Warner TD, Vojnovic I, Giuliano F, Jiménez R, Bishop-Bailey D, Mitchell JAet al., 2004, Cyclooxygenases 1, 2, and 3 and the production of prostaglandin I<sub>2</sub>:: Investigating the activities of acetaminophen and cyclooxygenase-2-selective inhibitors in rat tissues, JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, Vol: 310, Pages: 642-647, ISSN: 0022-3565

Journal article

Warner TD, Mitchell JA, 2004, Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic, FASEB JOURNAL, Vol: 18, Pages: 790-804, ISSN: 0892-6638

Journal article

Stanford SJ, Walters MJ, Mitchell JA, 2004, Carbon monoxide inhibits endothelin-1 release by human pulmonary artery smooth muscle cells, EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 486, Pages: 349-352, ISSN: 0014-2999

Journal article

Warner TD, Mitchell JA, 2003, HIF, stretching to get control of VEGF., Clin Sci (Lond), Vol: 105, Pages: 393-394, ISSN: 0143-5221

Mechanical forces are key regulators of cell function, particularly of cells within the arterial wall that are exposed to the shear stress and pulsatile pressure of flowing blood. The finding by Chang and colleagues in this issue of Clinical Science that cell stretch can up-regulate the expression of hypoxia-inducible factor-1alpha and vascular endothelial growth factor, which is a key regulator of blood vessel remodelling, provides us with further insight into the mechanisms underlying remodelling at sites of occlusive disease within the cardiovascular system.

Journal article

Woods M, Wood EG, Bardswell SC, Bishop-Bailey D, Barker S, Wort SJ, Mitchell JA, Warner TDet al., 2003, Role for nuclear factor-κB and signal transducer and activator of transcription 1/interferon regulatory factor-1 in cytokine-induced endothelin-1 release in human vascular smooth muscle cells, MOLECULAR PHARMACOLOGY, Vol: 64, Pages: 923-931, ISSN: 0026-895X

Journal article

Stanford SJ, San H, Nabel EG, Hislop AA, Haworth SG, Mitchell JAet al., 2003, Induction of heme oxygenase-1 in the murine lung afterbirth does not influence vascular remodelling, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188

Conference paper

Fleet MR, Anandarajah J, Walters MJ, Belcher PE, Sriskandan S, Mitchell JAet al., 2003, Cigarette smoke inhibits the induction of NOSII activity in murine macrophages stimulated with Gram negative bacteria, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188

Conference paper

Harrington LS, Mitchell JA, 2003, Activation of P2X-like receptors in rat isolated 2<SUP>nd</SUP> order mesenteric arteries induces vasodilation:: Role of EDHF, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188

Conference paper

Somuyiwa A, Stanford S, Gitlin J, Vojnovic I, Warner TD, Hislop A, Howarth S, Mitchell JAet al., 2003, Cyclo-oxygenase-2 expression in the lung in the period of pulmonary development after birth, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188

Conference paper

Anandarajah J, Fleet MR, Walters MJ, Belcher PE, Sriskandan S, Mitchell JAet al., 2003, Gram positive and Gram negative bacteria synergise to cause nitric oxide synthase induction in murine macrophages, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188

Conference paper

Jimenez R, Warner TD, Belcher PE, Vojnovic I, Mitchell JAet al., 2003, Induction of NOSII and COX activity in primary cultures of murine smooth muscle cells, Meeting of the British-Pharmacological-Society, Publisher: NATURE PUBLISHING GROUP, ISSN: 0007-1188

Conference paper

Warner TD, Mitchell JA, 2003, Nonsteroidal antiinflammatory drugs inhibiting prostanoid efflux: As easy as ABC?, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 100, Pages: 9108-9110, ISSN: 0027-8424

Journal article

Stanford SJ, Walters MJ, Hislop AA, Haworth SG, Evans TW, Mann BE, Motterlini R, Mitchell JAet al., 2003, Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role, EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 473, Pages: 135-141, ISSN: 0014-2999

Journal article

Price S, Mitchell JA, Anning PB, Evans TWet al., 2003, Type II nitric oxide synthase activity is cardio-protective in experimental sepsis, EUROPEAN JOURNAL OF PHARMACOLOGY, Vol: 472, Pages: 111-118, ISSN: 0014-2999

Journal article

Mistry H, Gitlin JM, Mitchell JA, Hiley CRet al., 2003, Endothelium-dependent relaxation and endothelial hyperpolarization by P2Y receptor agonists in rat-isolated mesenteric artery, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 139, Pages: 661-671, ISSN: 0007-1188

Journal article

Stanford SJ, Walters MJ, Hislop AA, Haworth SG, Evans TW, Mitchell JAet al., 2003, Heme oxygenase is expressed in human pulmonary artery smooth muscle where carbon monoxide has an anti-proliferative role, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: NATURE PUBLISHING GROUP, Pages: U26-U26, ISSN: 0007-1188

Conference paper

Walters MJ, Warner TD, Bishop-Bailey D, Mitchell JAet al., 2003, The PPARγ ligand 15-deoxy-Δ<SUP>12,14</SUP>-prostaglandin J<sub>2</sub> (15D-PGJ<sub>2</sub>) inhibits proliferation and cytokine release from human pulmonary artery smooth muscle, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: NATURE PUBLISHING GROUP, Pages: U66-U66, ISSN: 0007-1188

Conference paper

Stanford SJ, San H, Nabel EG, Hislop AA, Haworth SG, Mitchell JAet al., 2003, Heme oxygenase-1 deficient mice do not appear to have pulmonary hypertension, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U25-U25, ISSN: 0007-1188

Conference paper

Belcher E, Evans TW, Sriskandan S, Mitchell JAet al., 2003, Gram-positive <i>Staphylococcus aureus</i> contrasts with Gram-negative <i>Escherichia coli</i> in the induction of tumour necrosis factor-alpha and nitric oxide from macrophages in urine, Meeting of the Intensive-Care-Society, Publisher: OXFORD UNIV PRESS, Pages: 540P-541P, ISSN: 0007-0912

Conference paper

Belcher E, Evans TW, Sriskandan S, Mitchell JAet al., 2003, Staphylococcus aureus induces nitric oxide release in cardiovascular tissue via a toll like receptor 2-independent pathway, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U16-U16, ISSN: 0007-1188

Conference paper

Stanford SJ, Hislop AA, Haworth SG, Mitchell JAet al., 2003, Induction of heme oxygenase-1 in the porcine lung after birth, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U25-U25, ISSN: 0007-1188

Conference paper

Belcher E, Evans TW, Sriskandan S, Mitchell JAet al., 2003, Escherichia coli induces nitric oxide release in cardiovascular tissue via a toll like receptor 4-independent pathway, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U16-U16, ISSN: 0007-1188

Conference paper

Walters MJ, Mitchell JA, 2003, Cigarette smoke extract (CSE) stimulates human THP-1 monocytes directly and synergises with IL-1β to release IL-8, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: NATURE PUBLISHING GROUP, Pages: U22-U22, ISSN: 0007-1188

Conference paper

Patel HJ, Belvisi MG, Bishop-Bailey D, Yacoub MH, Mitchell JAet al., 2003, Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: Relevance for chronic obstructive pulmonary-disease therapy, JOURNAL OF IMMUNOLOGY, Vol: 170, Pages: 2663-2669, ISSN: 0022-1767

Journal article

Gray PA, Warner TD, Vojnovic I, Del Soldato P, Parikh A, Scadding GK, Mitchell JAet al., 2002, Effects of non-steroidal anti-inflammatory drugs on cyclooxygenase and lipoxygenase activity in whole blood from aspirin-sensitive asthmatics vs healthy donors, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 137, Pages: 1031-1038, ISSN: 0007-1188

Journal article

Belcher E, Evans TW, Sriskandan S, Mitchell JAet al., 2002, The main site of iNOS activity induced by Gram postive <i>Staphylococcus aureus</i> may be blood vessels and not macrophages:: Comparisons with Gram negative <i>Escherichia coli</i>, Winter Meeting of the British-Thoracic-Society, Publisher: BRITISH MED JOURNAL PUBL GROUP, ISSN: 0040-6376

Conference paper

Calatayud S, Warner TD, Breese EJ, Mitchell JAet al., 2002, Modulation by colony stimulating factors of human epithelial colon cancer cell apoptosis, CYTOKINE, Vol: 20, Pages: 163-167, ISSN: 1043-4666

Journal article

Warner TD, Mitchell JA, Vane JR, 2002, Cyclo-oxygenase-2 inhibitors and cardiovascular events, LANCET, Vol: 360, Pages: 1700-1701, ISSN: 0140-6736

Journal article

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