Imperial College London
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ProfessorJamesBarlow

Business School

Chair in Technology and Innovation Management
 
 
 
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Contact

 

+44 (0)20 7594 5936j.barlow Website CV

 
 
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Assistant

 

Mrs Lorraine Sheehy +44 (0)20 7594 9173

 
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Location

 

Room 197EBusiness School BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Huddy:2015:10.1136/bmjopen-2015-007840,
author = {Huddy, JR and Ni, M and Mavroveli, S and Barlow, J and Williams, DA and Hanna, GB},
doi = {10.1136/bmjopen-2015-007840},
journal = {BMJ Open},
pages = {e007840--e007840},
title = {A research protocol for developing a Point-Of-Care Key Evidence Tool 'POCKET': a checklist for multidimensional evidence reporting on point-of-care in vitro diagnostics.},
url = {http://dx.doi.org/10.1136/bmjopen-2015-007840},
volume = {5},
year = {2015}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - INTRODUCTION: Point-of-care in vitro diagnostics (POC-IVD) are increasingly becoming widespread as an acceptable means of providing rapid diagnostic results to facilitate decision-making in many clinical pathways. Evidence in utility, usability and cost-effectiveness is currently provided in a fragmented and detached manner that is fraught with methodological challenges given the disruptive nature these tests have on the clinical pathway. The Point-of-care Key Evidence Tool (POCKET) checklist aims to provide an integrated evidence-based framework that incorporates all required evidence to guide the evaluation of POC-IVD to meet the needs of policy and decisionmakers in the National Health Service (NHS). METHODS AND ANALYSIS: A multimethod approach will be applied in order to develop the POCKET. A thorough literature review has formed the basis of a robust Delphi process and validation study. Semistructured interviews are being undertaken with POC-IVD stakeholders, including industry, regulators, commissioners, clinicians and patients to understand what evidence is required to facilitate decision-making. Emergent themes will be translated into a series of statements to form a survey questionnaire that aims to reach a consensus in each stakeholder group to what needs to be included in the tool. Results will be presented to a workshop to discuss the statements brought forward and the optimal format for the tool. Once assembled, the tool will be field-tested through case studies to ensure validity and usability and inform refinement, if required. The final version will be published online with a call for comments. Limitations include unpredictable sample representation, development of compromise position rather than consensus, and absence of blinding in validation exercise. ETHICS AND DISSEMINATION: The Imperial College Joint Research Compliance Office and the Imperial College Hospitals NHS Trust R&D department have approved the protocol. The checklist tool will be
AU  - Huddy,JR
AU  - Ni,M
AU  - Mavroveli,S
AU  - Barlow,J
AU  - Williams,DA
AU  - Hanna,GB
DO  - 10.1136/bmjopen-2015-007840
EP  - 007840
PY  - 2015///
SN  - 2044-6055
SP  - 007840
TI  - A research protocol for developing a Point-Of-Care Key Evidence Tool 'POCKET': a checklist for multidimensional evidence reporting on point-of-care in vitro diagnostics.
T2  - BMJ Open
UR  - http://dx.doi.org/10.1136/bmjopen-2015-007840
UR  - http://hdl.handle.net/10044/1/25191
VL  - 5
ER  -
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