Imperial College London

DrJanineBosse

Faculty of MedicineDepartment of Infectious Disease

Senior Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 1803j.bosse

 
 
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Location

 

234Wright Fleming WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Bosse:2017:10.1128/JCM.02166-16,
author = {Bosse, JT and Li, Y and Sárközi, R and Gottschalk, M and Angen, O and Nedbalcova, K and Rycroft, AN and Fodor, L and Langford, PR},
doi = {10.1128/JCM.02166-16},
journal = {Journal of Clinical Microbiology},
pages = {902--907},
title = {A unique capsule locus in the newly designated Actinobacillus pleuropneumoniae serovar 16 and development of a diagnostic PCR assay},
url = {http://dx.doi.org/10.1128/JCM.02166-16},
volume = {55},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Actinobacillus pleuropneumoniae causes pleuropneumonia, an economically significant, lung disease of pigs. Recently, isolates of A. pleuropneumoniae that were serologically distinct from the previously characterized 15 serovars were described, and a proposal put forward that they comprised a new serovar 16. Here we used whole genome sequencing of the proposed serovar 16 reference strain A-85/14 to confirm presence of a unique capsular polysaccharide biosynthetic locus. For molecular diagnostics, primers were designed from the capsule locus of A-85/14 and a PCR formulated that differentiated serovar 16 isolates from all 15 known serovars, and other common respiratory pathogenic/commensal bacteria of pigs. Analysis of the capsule locus of strain A-85/14 combined with the previous serological data, show the existence of a sixteenth serovar – designated serovar 16 - of A. pleuropneumoniae.
AU - Bosse,JT
AU - Li,Y
AU - Sárközi,R
AU - Gottschalk,M
AU - Angen,O
AU - Nedbalcova,K
AU - Rycroft,AN
AU - Fodor,L
AU - Langford,PR
DO - 10.1128/JCM.02166-16
EP - 907
PY - 2017///
SN - 1098-660X
SP - 902
TI - A unique capsule locus in the newly designated Actinobacillus pleuropneumoniae serovar 16 and development of a diagnostic PCR assay
T2 - Journal of Clinical Microbiology
UR - http://dx.doi.org/10.1128/JCM.02166-16
UR - http://hdl.handle.net/10044/1/43600
VL - 55
ER -