Imperial College London
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DrJanineBosse

Faculty of Medicine, Department of Infectious Disease

Honorary Senior Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 1803j.bosse

 
 
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Location

 

234Wright Fleming WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Bosse:2017:10.1128/JCM.02166-16,
author = {Bosse, JT and Li, Y and Sárközi, R and Gottschalk, M and Angen, O and Nedbalcova, K and Rycroft, AN and Fodor, L and Langford, PR},
doi = {10.1128/JCM.02166-16},
journal = {Journal of Clinical Microbiology},
pages = {902--907},
title = {A unique capsule locus in the newly designated Actinobacillus pleuropneumoniae serovar 16 and development of a diagnostic PCR assay},
url = {http://dx.doi.org/10.1128/JCM.02166-16},
volume = {55},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Actinobacillus pleuropneumoniae causes pleuropneumonia, an economically significant, lung disease of pigs.  Recently, isolates of A. pleuropneumoniae that were serologically distinct from the previously characterized 15 serovars were described, and a proposal put forward that they comprised a new serovar 16. Here we used whole genome sequencing of the proposed serovar 16 reference strain A-85/14 to confirm presence of a unique capsular polysaccharide biosynthetic locus. For molecular diagnostics, primers were designed from the capsule locus of A-85/14 and a PCR formulated that differentiated serovar 16 isolates from all 15 known serovars, and other common respiratory pathogenic/commensal bacteria of pigs. Analysis of the capsule locus of strain A-85/14 combined with the previous serological data, show the existence of a sixteenth serovar – designated serovar 16 - of A. pleuropneumoniae.
AU  - Bosse,JT
AU  - Li,Y
AU  - Sárközi,R
AU  - Gottschalk,M
AU  - Angen,O
AU  - Nedbalcova,K
AU  - Rycroft,AN
AU  - Fodor,L
AU  - Langford,PR
DO  - 10.1128/JCM.02166-16
EP  - 907
PY  - 2017///
SN  - 1098-660X
SP  - 902
TI  - A unique capsule locus in the newly designated Actinobacillus pleuropneumoniae serovar 16 and development of a diagnostic PCR assay
T2  - Journal of Clinical Microbiology
UR  - http://dx.doi.org/10.1128/JCM.02166-16
UR  - http://hdl.handle.net/10044/1/43600
VL  - 55
ER  -
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