Imperial College London


Faculty of MedicineDepartment of Medicine

Chair in Infectious Diseases and Immunity



+44 (0)20 3313 8521j.friedland Website




Miss Amy Cock +44 (0)20 3313 1943




8N21ACommonwealth BuildingHammersmith Campus





Brief Biosketch

Professor Jon Friedland is Campus Director of the Hammersmith Campus and Head of Infectious Diseases and Immunity at Imperial College London. He is an Honorary Consultant in Infectious Diseases at Imperial College Healthcare NHS Trust. Jon Friedland graduated in medicine from Cambridge University and Kings College, London University.  After medical training at London Postgraduate Hospitals and the John Radcliffe Hospital in Oxford, he completed a PhD as part of a MRC Training Fellowship.  He was appointed Senior Lecturer/Hon Consultant at the Royal Postgraduate Medical School in 1993 becoming Reader at Imperial College in 2000 and Departmental Chair in 2004.

His major research interest is in innate immune response and particularly the role of matrix metalloproteinase’s in the immunopathology of tuberculosis and the development of novel therapeutic approaches. Other interests are in the development of novel diagnostics for tuberculosis and migrant health. During the course of his research, he has published over 190 peer reviewed papers, invited editorials and reviews as well as 3 books.  Our Research team won the Medical Futures Innovations Award for best overall innovation (from 1200).  In 2005, Jon Friedland was awarded the Royal College of Physicians Weber-Parkes Prize Medal for research in tuberculosis. He was elected Fellow of the Academy of Medical Sciences in 2008 and a Fellow of the Royal College of Physicians of Ireland in 2010.


Selected Publications

Journal Articles

Elkington P, Shiomi T, Breen R, et al., 2011, MMP-1 drives immunopathology in human tuberculosis and transgenic mice, Journal of Clinical Investigation, Vol:121, ISSN:0021-9738, Pages:1827-1833

Fitzwater SP, Caviedes L, Gilman RH, et al., 2010, Prolonged Infectiousness of Tuberculosis Patients in a Directly Observed Therapy Short-Course Program with Standardized Therapy, Clinical Infectious Diseases, Vol:51, ISSN:1058-4838, Pages:371-378

Green JA, Elkington PT, Pennington CJ, et al., 2010, Mycobacterium tuberculosis Upregulates Microglial Matrix Metalloproteinase-1 and-3 Expression and Secretion via NF-kappa B- and Activator Protein-1-Dependent Monocyte Networks, Journal of Immunology, Vol:184, ISSN:0022-1767, Pages:6492-6503

Escombe AR, Moore DAJ, Gilman RH, et al., 2009, Upper-Room Ultraviolet Light and Negative Air Ionization to Prevent Tuberculosis Transmission, PLOS Medicine, Vol:6, ISSN:1549-1277

Escombe AR, Moore DAJ, Gilman RH, et al., 2008, The Infectiousness of Tuberculosis Patients Coinfected with HIV, PLOS Medicine, Vol:5, ISSN:1549-1277, Pages:1387-1397

Sheen P, O'Kane CM, Chaudhary K, et al., 2009, High MMP-9 activity characterises pleural tuberculosis correlating with granuloma formation, European Respiratory Journal, Vol:33, ISSN:0903-1936, Pages:134-141

More Publications