Imperial College London

ProfessorJonathanFriedland

Faculty of MedicineDepartment of Medicine

Chair in Infectious Diseases and Immunity
 
 
 
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Contact

 

+44 (0)20 3313 8521j.friedland Website

 
 
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Assistant

 

Miss Amy Cock +44 (0)20 3313 1943

 
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Location

 

8N21ACommonwealth BuildingHammersmith Campus

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Summary

 

Summary

Brief Biosketch

Professor Jon Friedland is Campus Director of the Hammersmith Campus and Head of Infectious Diseases and Immunity at Imperial College London. He is an Honorary Consultant in Infectious Diseases at Imperial College Healthcare NHS Trust. Jon Friedland graduated in medicine from Cambridge University and Kings College, London University.  After medical training at London Postgraduate Hospitals and the John Radcliffe Hospital in Oxford, he completed a PhD as part of a MRC Training Fellowship.  He was appointed Senior Lecturer/Hon Consultant at the Royal Postgraduate Medical School in 1993 becoming Reader at Imperial College in 2000 and Departmental Chair in 2004.

His major research interest is in innate immune response and particularly the role of matrix metalloproteinase’s in the immunopathology of tuberculosis and the development of novel therapeutic approaches. Other interests are in the development of novel diagnostics for tuberculosis and migrant health. During the course of his research, he has published over 190 peer reviewed papers, invited editorials and reviews as well as 3 books.  Our Research team won the Medical Futures Innovations Award for best overall innovation (from 1200).  In 2005, Jon Friedland was awarded the Royal College of Physicians Weber-Parkes Prize Medal for research in tuberculosis. He was elected Fellow of the Academy of Medical Sciences in 2008 and a Fellow of the Royal College of Physicians of Ireland in 2010.

 

Selected Publications

Journal Articles

Ong CWM, Pabisiak PJ, Brilha S, et al., 2017, Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis, Journal of Neuroinflammation, Vol:14, ISSN:1742-2094

Hargreaves S, Nellums L, Friedland JS, 2016, Time to rethink approaches to migrant health screening, The Lancet, Vol:388, ISSN:0140-6736, Pages:2456-2457

Ong CWM, Elkington PT, Brilha S, et al., 2015, Neutrophil-Derived MMP-8 Drives AMPK-Dependent Matrix Destruction in Human Pulmonary Tuberculosis, PLOS Pathogens, Vol:11, ISSN:1553-7366

Singh S, Saraiva L, Elkington PTG, et al., 2014, Regulation of matrix metalloproteinase-1,-3, and-9 in Mycobacterium tuberculosis-dependent respiratory networks by the rapamycin- sensitive PI3K/p70(S6K) cascade, The FASEB Journal, Vol:28, ISSN:0892-6638, Pages:85-93

Elkington P, Shiomi T, Breen R, et al., 2011, MMP-1 drives immunopathology in human tuberculosis and transgenic mice, Journal of Clinical Investigation, Vol:121, ISSN:0021-9738, Pages:1827-1833

More Publications