Imperial College London
Alternate

ProfessorJonFriedland

Faculty of Medicine, Department of Infectious Disease

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 3313 8521j.friedland Website

 
 
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Assistant

 

Ms Teyanna Gaeta +44 (0)20 3313 1943

 
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Location

 

8N21ACommonwealth BuildingHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

250 results found

Jellis J, Evans C, Hughes S, Friedland JSet al., 1996, Presumed Pott's disease, LANCET, Vol: 347, Pages: 476-477, ISSN: 0140-6736

Journal article

Friedland JS, Hartley JC, Hartley CGC, Shattock RJ, Griffin GEet al., 1996, Cytokine secretion in vivo and ex vivo following chemotherapy of Mycobacterium tuberculosis infection, TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, Vol: 90, Pages: 199-203, ISSN: 0035-9203

Journal article

Friedland JS, Shaw TC, Zhao L, Stylianou Eet al., 1996, Phagocytosis of zymosan but not of latex by human monocytic cells activates the NF-kappa B family of transcription factors and IL-8 secretion., JOURNAL OF LEUKOCYTE BIOLOGY, Pages: 201-201, ISSN: 0741-5400

Journal article

FRIEDLAND JS, PORTER JC, 1995, CYTOKINE THERAPY IN SEPTIC SHOCK, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 333, Pages: 942-942, ISSN: 0028-4793

Journal article

Biswas S, Friedland JS, Remick DG, Davies EG, Sharland Met al., 1995, Elevated plasma interleukin 8 in respiratory syncytial virus bronchiolitis., Pediatr Infect Dis J, Vol: 14, ISSN: 0891-3668

Journal article

BISWAS S, FRIEDLAND JS, REMICK DG, DAVIES EG, SHARLAND Met al., 1995, ELEVATED PLASMA INTERLEUKIN-8 IN RESPIRATORY SYNCYTIAL VIRUS BRONCHIOLITIS, PEDIATRIC INFECTIOUS DISEASE JOURNAL, Vol: 14, Pages: 919-919, ISSN: 0891-3668

Journal article

FRIEDLAND JS, HARTLEY JC, HARTLEY CGC, SHATTOCK RJ, GRIFFIN GEet al., 1995, INHIBITION OF EX-VIVO PROINFLAMMATORY CYTOKINE SECRETION IN FATAL MYCOBACTERIUM-TUBERCULOSIS INFECTION, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Vol: 100, Pages: 233-238, ISSN: 0009-9104

Journal article

FRIEDLAND JS, 1995, CHEMOKINES AND HUMAN INFECTION, CLINICAL SCIENCE, Vol: 88, Pages: 393-400, ISSN: 0143-5221

Journal article

PORTER JC, FRIEDLAND JS, FREEDMAN AR, 1994, TUBERCULOUS BRONCHOESOPHAGEAL FISTULAS IN PATIENTS INFECTED WITH THE HUMAN-IMMUNODEFICIENCY-VIRUS - 3 CASE-REPORTS AND REVIEW, CLINICAL INFECTIOUS DISEASES, Vol: 19, Pages: 954-957, ISSN: 1058-4838

Journal article

FRIEDLAND JS, 1994, HICCUPS, TOXOPLASMOSIS, AND AIDS, CLINICAL INFECTIOUS DISEASES, Vol: 18, Pages: 835-835, ISSN: 1058-4838

Journal article

Friedland JS, 1994, Hiccups, toxoplasmosis, and AIDS., Clin Infect Dis, Vol: 18, ISSN: 1058-4838

Journal article

FRIEDLAND JS, 1994, CHEMOTACTIC CYTOKINES AND TUBERCULOSIS, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 22, Pages: 310-312, ISSN: 0300-5127

Journal article

SHATTOCK RJ, FRIEDLAND JS, GRIFFIN GE, 1994, PHAGOCYTOSIS OF MYCOBACTERIUM-TUBERCULOSIS MODULATES HUMAN-IMMUNODEFICIENCY-VIRUS REPLICATION IN HUMAN MONOCYTIC CELLS, JOURNAL OF GENERAL VIROLOGY, Vol: 75, Pages: 849-856, ISSN: 0022-1317

Journal article

Shattock RJ, Friedland JS, Griffin GE, 1994, Phagocytosis of Mycobacterium tuberculosis modulates human immunodeficiency virus replication in human monocytic cells., J Gen Virol, Vol: 75 ( Pt 4), Pages: 849-856, ISSN: 0022-1317

Macrophage activation resulting from phagocytosis has the potential to modulate human immunodeficiency virus (HIV) replication. We have determined the effects of phagocytosis of particulate stimuli on transcription and release of HIV. Using THP-1 and Mono Mac 6 human monocytic cell lines transfected with HIV long terminal repeat sequence chloramphenicol acetyltransferase (LTR CAT) constructs we have demonstrated that phagocytosis of Mycobacterium tuberculosis enhanced HIV-1 and -2 LTR CAT expression. However phagocytosis of zymosan or inert latex beads had little or no effect on CAT expression. Enhancement of HIV LTR CAT expression was dependent upon intact NF-kappa B binding sites and was independent of tumour necrosis factor alpha secretion. M. tuberculosis strains of different degrees of virulence induced similar levels of enhanced CAT expression. In contrast, phagocytosis of M. tuberculosis by HIV-1-infected THP-1 cells reduced supernatant reverse transcriptase (RT) activity without suppression of p24 antigen release. Phagocytosis of zymosan granules or latex particles did not alter released RT activity. However, phagocytosis of either M. tuberculosis, zymosan granules or latex particles by HIV-1-infected human peripheral blood monocyte-derived macrophages reduced supernatant RT activity. These data indicate that phagocytosis of M. tuberculosis may enhance HIV transcription in monocytic cells although it may reduce release of intact HIV.

Journal article

FRIEDLAND JS, 1994, MYCOBACTERIA, CHRONIC INFLAMMATION AND THE GRANULOMA, BAILLIERES CLINICAL INFECTIOUS DISEASES, Vol: 1, Pages: 51-64, ISSN: 1071-6564

Journal article

Friedland JS, Jeffrey I, Griffin GE, Booker M, Courtenay-Evans Ret al., 1994, Q fever and intrauterine death., Lancet, Vol: 343, ISSN: 0140-6736

Journal article

FRIEDLAND JS, JEFFREY I, GRIFFIN GE, BOOKER M, COURTENAYEVANS Ret al., 1994, Q-FEVER AND INTRAUTERINE DEATH, LANCET, Vol: 343, Pages: 288-288, ISSN: 0140-6736

Journal article

SHATTOCK RJ, FRIEDLAND JS, GRIFFIN GE, 1993, RELEASE OF HUMAN-IMMUNODEFICIENCY-VIRUS BY THP-1 CELLS AND HUMAN MACROPHAGES IS REGULATED BY CELLULAR ADHERENCE AND ACTIVATION, JOURNAL OF VIROLOGY, Vol: 67, Pages: 3569-3575, ISSN: 0022-538X

Journal article

FRIEDLAND JS, 1993, CYTOKINES, PHAGOCYTOSIS, AND MYCOBACTERIUM-TUBERCULOSIS, LYMPHOKINE AND CYTOKINE RESEARCH, Vol: 12, Pages: 127-133, ISSN: 0277-6766

Journal article

FRIEDLAND JS, SHATTOCK RJ, GRIFFIN GE, 1993, PHAGOCYTOSIS OF MYCOBACTERIUM-TUBERCULOSIS OR PARTICULATE STIMULI BY HUMAN MONOCYTIC CELLS INDUCES EQUIVALENT MONOCYTE CHEMOTACTIC PROTEIN-1 GENE-EXPRESSION, CYTOKINE, Vol: 5, Pages: 150-156, ISSN: 1043-4666

Journal article

FRIEDLAND JS, SHATTOCK RJ, JOHNSON JD, REMICK DG, HOLLIMAN RE, GRIFFIN GEet al., 1993, DIFFERENTIAL CYTOKINE GENE-EXPRESSION AND SECRETION AFTER PHAGOCYTOSIS BY A HUMAN MONOCYTIC CELL-LINE OF TOXOPLASMA-GONDII COMPARED WITH MYCOBACTERIUM-TUBERCULOSIS, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Vol: 91, Pages: 282-286, ISSN: 0009-9104

Journal article

SHATTOCK RJ, FRIEDLAND JS, GRIFFIN GE, 1993, MODULATION OF HIV TRANSCRIPTION IN AND RELEASE FROM HUMAN MONOCYTIC CELLS FOLLOWING PHAGOCYTOSIS OF MYCOBACTERIUM-TUBERCULOSIS, RESEARCH IN VIROLOGY, Vol: 144, Pages: 7-12, ISSN: 0923-2516

Journal article

FRIEDLAND JS, SHATTOCK R, REMICK DG, GRIFFIN GEet al., 1993, MYCOBACTERIAL 65-KD HEAT-SHOCK PROTEIN INDUCES RELEASE OF PROINFLAMMATORY CYTOKINES FROM HUMAN MONOCYTIC CELLS, CLINICAL AND EXPERIMENTAL IMMUNOLOGY, Vol: 91, Pages: 58-62, ISSN: 0009-9104

Journal article

FRIEDLAND JS, SMITH S, LEDINGHAM JGG, 1992, CONTINUOUS CATHETER DRAINAGE OF STREPTOCOCCUS-PNEUMONIAE PERICARDIAL-EFFUSION, JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, Vol: 85, Pages: 762-763, ISSN: 0141-0768

Journal article

FRIEDLAND JS, REMICK DG, SHATTOCK R, GRIFFIN GEet al., 1992, SECRETION OF INTERLEUKIN-8 FOLLOWING PHAGOCYTOSIS OF MYCOBACTERIUM-TUBERCULOSIS BY HUMAN MONOCYTE CELL-LINES, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 22, Pages: 1373-1378, ISSN: 0014-2980

Journal article

FRIEDLAND JS, SUPUTTAMONGKOL Y, REMICK DG, CHAOWAGUL W, STRIETER RM, KUNKEL SL, WHITE NJ, GRIFFIN GEet al., 1992, PROLONGED ELEVATION OF INTERLEUKIN-8 AND INTERLEUKIN-6 CONCENTRATIONS IN PLASMA AND OF LEUKOCYTE INTERLEUKIN-8 MESSENGER-RNA LEVELS DURING SEPTICEMIC AND LOCALIZED PSEUDOMONAS-PSEUDOMALLEI INFECTION, INFECTION AND IMMUNITY, Vol: 60, Pages: 2402-2408, ISSN: 0019-9567

Journal article

FRIEDLAND JS, PATERSON DJ, 1991, EXERTIONAL FATIGUE IN DISORDERS OF MUSCLE, NEW ENGLAND JOURNAL OF MEDICINE, Vol: 324, Pages: 1896-1897, ISSN: 0028-4793

Journal article

FRIEDLAND JS, WARRELL DA, 1991, THE JARISCH-HERXHEIMER REACTION IN LEPTOSPIROSIS - POSSIBLE PATHOGENESIS AND REVIEW, REVIEWS OF INFECTIOUS DISEASES, Vol: 13, Pages: 207-210, ISSN: 0162-0886

Journal article

Friedland JS, Iveson TJ, Fraise AP, Winearls CG, Selkon JB, Oliver DOet al., 1990, A comparison between intraperitoneal ciprofloxacin and intraperitoneal vancomycin and gentamicin in the treatment of peritonitis associated with continuous ambulatory peritoneal dialysis (CAPD)., J Antimicrob Chemother, Vol: 26 Suppl F, Pages: 77-81, ISSN: 0305-7453

In a prospective, randomized, controlled trial in 40 patients, intraperitoneal ciprofloxacin was shown to be as effective as the currently recommended regimen of intraperitoneal vancomycin and gentamicin for the treatment of CAPD peritonitis. There was one treatment failure in the ciprofloxacin arm and four in the comparative arm. A single drug regimen is preferred by patients. The intraperitoneal route of administration of ciprofloxacin therapy has advantages over the oral route.

Journal article

FRIEDLAND JS, IVESON TJ, FRAISE AP, WINEARLS CG, SELKON JB, OLIVER DOet al., 1990, A COMPARISON BETWEEN INTRAPERITONEAL CIPROFLOXACIN AND INTRAPERITONEAL VANCOMYCIN AND GENTAMICIN IN THE TREATMENT OF PERITONITIS ASSOCIATED WITH CONTINUOUS AMBULATORY PERITONEAL-DIALYSIS (CAPD), MEETING ON CIPROFLOXACIN : DEFINING ITS ROLE TODAY, Publisher: W B SAUNDERS CO LTD, Pages: 77-81, ISSN: 0305-7453

Conference paper

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