Jethro Herberg is a Clinical Lecturer and Honorary Consultant in Paediatric Infectious Diseases working at St Mary’s Hospital, London and at Imperial College.
Host inflammatory responses are major contributors to disease pathophysiology, and analysis of host gene expression in different infection and inflammatory states can offer insights which may open the door to new therapies and diagnostic approaches.
At St Mary’s Hospital, London, Dr Herberg is recruiting children presenting with infections and inflammatory conditions to prospective, observational studies which aim to identify pathogen-specific signatures of gene and protein expression, and to identify pathways implicated in patients with severe disease.
Herberg JA, Kaforou M, Wright VJ, 2017, Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children (vol 316, pg 835, 2016), Jama-journal of the American Medical Association, Vol:317, ISSN:0098-7484, Pages:538-538
et al., 2017, Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity, Cell, Vol:168, ISSN:0092-8674, Pages:789-+
et al., 2017, Diagnosis of Bacterial Infection Using a 2-Transcript Host RNA Signature in Febrile Infants 60 Days or Younger, Jama-journal of the American Medical Association, Vol:317, ISSN:0098-7484, Pages:1577-1578
MacDermott N, Herberg JA, 2017, Ebola: lessons learned, Paediatrics & Child Health, Vol:27, ISSN:1205-7088, Pages:128-134
et al., 2016, Does Viral Co-Infection Influence the Severity of Acute Respiratory Infection in Children?, Plos One, Vol:11, ISSN:1932-6203