Imperial College London
Portrait Picture

Professor Jonathan Jeffers

Faculty of Engineering, Department of Mechanical Engineering

Interim Associate Dean Enterprise for Faculty of Engineering
 
 
 
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Contact

 

+44 (0)20 7594 5471j.jeffers

 
 
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Location

 

715City and Guilds BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Parkes:2017:10.1016/j.jbiomech.2017.06.004,
author = {Parkes, M and Cann, P and Jeffers, J},
doi = {10.1016/j.jbiomech.2017.06.004},
journal = {Journal of Biomechanics},
pages = {261--265},
title = {Real-time observation of fluid flows in tissue during stress relaxation using Raman spectroscopy},
url = {http://dx.doi.org/10.1016/j.jbiomech.2017.06.004},
volume = {60},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - This paper outlines a technique to measure fluid levels in articular cartilage tissue during an unconfined stress relaxation test. A time series of Raman spectrum were recorded during relaxation and the changes in the specific Raman spectral bands assigned to water and protein were monitored to determine the fluid content of the tissue. After 1000 s unconfined compression the fluid content of the tissue is reduced by an average of 3.9% ± 1.7%. The reduction in fluid content during compression varies between samples but does not significantly increase with increasing strain. Further development of this technique will allow mapping of fluid distribution and flows during dynamic testing making it a powerful tool to understand the role of interstitial fluid in the functional performance of cartilage.
AU  - Parkes,M
AU  - Cann,P
AU  - Jeffers,J
DO  - 10.1016/j.jbiomech.2017.06.004
EP  - 265
PY  - 2017///
SN  - 1873-2380
SP  - 261
TI  - Real-time observation of fluid flows in tissue during stress relaxation using Raman spectroscopy
T2  - Journal of Biomechanics
UR  - http://dx.doi.org/10.1016/j.jbiomech.2017.06.004
UR  - http://hdl.handle.net/10044/1/49299
VL  - 60
ER  -
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