Imperial College London

MrJamesKinross

Faculty of MedicineDepartment of Surgery & Cancer

Clinical Senior Lecturer in Colorectal Surgery
 
 
 
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Contact

 

+44 (0)20 3312 1947j.kinross

 
 
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Location

 

1029Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Balog, J.; Kumar, S.; Alexander, J.; Golf, O.; Huang, J.; Wiggins,  T.; Abbassi-Ghadi, N.; Enyedi, A.; Kacska, S.; Kinross, J. et al. In Vivo Endoscopic Tissue Identification by Rapid Evaporative Ionization Mass Spectrometry (REIMS). Angew Chem Int Ed Engl 2015, 54, (38), 11059-62.

Marchesi, J. R.; Adams, D. H.; Fava, F.; Hermes, G. D.; Hirschfield, G. M.; Hold, G.; Quraishi, M. N.; Kinross, J.; Smidt, H.; Tuohy, K. M.; Thomas, L. V.; Zoetendal, E. G.; Hart, A., The gut microbiota and host health: a new clinical frontier. Gut 2015.

Penney, N. C.; Kinross, J. M.; Newton, R. C.; Purkayastha, S., The role of bile acids in reducing the metabolic complications of obesity after bariatric surgery: A systematic review. Int J Obes (Lond) 2015.

Tekkis, P.; Tan, E.; Kontovounisios, C.; Kinross, J.; Georgiou, C.; Rasheed, S.; Brown, G., Hand-sewn coloanal anastomosis for low rectal cancer; technique and long term outcome. Colorectal Dis 2015.

O’Keefe SJD, Li JV, Lahti L, Ou J, Carbonero F, Mohammed K, Posma JM, Kinross J, Wahl E, Ruder E et al: Fat, fibre and cancer risk in African Americans and rural Africans. Nat Commun 2015, 6, 6342 May  2015.

Scott AJ, Mason SE, Arunakirinathan M, Reissis Y, Kinross JM, Smith JJ: Risk stratification by the Appendicitis Inflammatory Response score to guide decision-making in patients with suspected appendicitis. The British journal of surgery 2015, 102(5):563-572.

Kontovounisios C, Kinross J, Tan E, Brown G, Rasheed S, Tekkis P: Complete mesocolic excision in colorectal cancer: a systematic review. Colorectal disease, 2015, 17(1):7-16.

Golf O, Strittmatter N, Karancsi T, Pringle SD, Speller AV, Mroz A, Kinross JM, Abbassi-Ghadi N, Jones EA, Takats Z: Rapid evaporative ionization mass spectrometry imaging platform for direct mapping from bulk tissue and bacterial growth media. Analytical chemistry 2015, 87(5):2527-2534.

Villasenor A, Kinross JM, Li JV, Penney N, Barton RH, Nicholson JK, Darzi A, Barbas C, Holmes E: 1H NMR global metabolic phenotyping of acute pancreatitis in the emergency unit. Journal of proteome research 2014, 13(12):5362-5375.

Veselkov KA, Mirnezami R, Strittmatter N, Goldin RD, Kinross J, Speller AV, Abramov T, Jones EA, Darzi A, Holmes E et al: Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America 2014, 111(3):1216-1221.

Mirnezami R, Spagou K, Vorkas PA, Lewis MR, Kinross J, Want E, Shion H, Goldin RD, Darzi A, Takats Z et al: Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects. Molecular oncology 2014, 8(1):39-49.

Mirnezami R, Jimenez B, Li JV, Kinross JM, Veselkov K, Goldin RD, Holmes E, Nicholson JK, Darzi A: Rapid diagnosis and staging of colorectal cancer via high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy of intact tissue biopsies. Annals of surgery 2014, 259(6):1138-1149.

Kontovounisios C, Baloyiannis Y, Kinross J, Tan E, Rasheed S, Tekkis P: Modified right colon inversion technique as a salvage procedure for colorectal or coloanal anastomosis. Colorectal disease, 2014, 16(12):971-975.

Kinross J, Li JV, Muirhead LJ, Nicholson J: Nutritional modulation of the metabonome: applications of metabolic phenotyping in translational nutritional research. Current opinion in gastroenterology 2014, 30(2):196-207.

Dumas ME, Kinross J, Nicholson JK: Metabolic phenotyping and systems biology approaches to understanding metabolic syndrome and fatty liver disease. Gastroenterology 2014, 146(1):46-62.

Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, Bellia A, Boccia S, Bousquet J, Cardaci V et al: A systems medicine clinical platform for understanding and managing non- communicable diseases. Current pharmaceutical design 2014, 20(38):5945-5956.

Lee H, Beales S, Kinross J, Burns E, Darzi A: The extent of rationing of surgical procedures in England. Lancet 2013, 381(9866):534-535.

Kinross JM, Markar S, Karthikesalingam A, Chow A, Penney N, Silk D, Darzi A: A meta-analysis of probiotic and synbiotic use in elective surgery: does nutrition modulation of the gut microbiome improve clinical outcome? JPEN Journal of parenteral and enteral nutrition 2013, 37(2):243-253.

Kinross JM, Drymousis P, Jimenez B, Frilling A: Metabonomic profiling: a novel approach in neuroendocrine neoplasias. Surgery 2013, 154(6):1185-1192; discussion 1192-1183.

Jimenez B, Mirnezami R, Kinross J, Cloarec O, Keun HC, Holmes E, Goldin RD, Ziprin P, Darzi A, Nicholson JK: 1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication. Journal of proteome research 2013, 12(2):959-968.

Balog J, Sasi-Szabo L, Kinross J, Lewis MR, Muirhead LJ, Veselkov K, Mirnezami R, Dezso B, Damjanovich L, Darzi A et al: Intraoperative tissue identification using rapid evaporative ionization mass spectrometry. Science translational medicine 2013, 5(194):194ra193.

Takats Z, Denes J, Kinross J: Identifying the margin: a new method to distinguish between cancerous and noncancerous tissue during surgery. Future oncology 2012, 8(2):113-116.

Patel V, Lee H, Taylor D, Aggarwal R, Kinross J, Darzi A: Virtual worlds are an innovative tool for medical device training in a simulated environment. Studies in health technology and informatics 2012, 173:338-343.

Nicholson JK, Holmes E, Kinross JM, Darzi AW, Takats Z, Lindon JC: Metabolic phenotyping in clinical and surgical environments. Nature 2012, 491(7424):384-392.

Nicholson JK, Holmes E, Kinross J, Burcelin R, Gibson G, Jia W, Pettersson S: Host-gut microbiota metabolic interactions. Science 2012, 336(6086):1262-1267.

Mirnezami R, Kinross JM, Vorkas PA, Goldin R, Holmes E, Nicholson J, Darzi A: Implementation of molecular phenotyping approaches in the personalized surgical patient journey. Annals of surgery 2012, 255(5):881-889.

Markar SR, Karthikesalingam A, Thrumurthy S, Muirhead L, Kinross J, Paraskeva P: Single-incision laparoscopic surgery (SILS) vs. conventional multiport cholecystectomy: systematic review and meta-analysis. Surgical endoscopy 2012, 26(5):1205-1213.

Markar SR, Blackburn S, Cobb R, Karthikesalingam A, Evans J, Kinross J, Faiz O: Laparoscopic versus open appendectomy for complicated and uncomplicated appendicitis in children. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012, 16(10):1993-2004.

Markar S, Kinross J: Authors' reply to: single-incision laparoscopic surgery (SILS) vs. conventional multiport cholecystectomy: systematic review and meta-analysis. Surgical Endoscopy and Other Interventional Techniques 2012, 26(10):3000-3001.

Kinross J, Nicholson JK: Gut microbiota: Dietary and social modulation of gut microbiota in the elderly. Nature reviews Gastroenterology & hepatology 2012, 9(10):563-564.

Holmes E, Kinross J, Gibson GR, Burcelin R, Jia W, Pettersson S, Nicholson JK: Therapeutic modulation of microbiota-host metabolic interactions. Science translational medicine 2012, 4(137):137rv136.

Markar SR, Venkat-Raman V, Ho A, Karthikesalingam A, Kinross J, Evans J, Bloom I: Laparoscopic versus open appendicectomy in obese patients. International journal of surgery 2011, 9(6):451-455.

Markar SR, Karthikesalingam AP, Venkat-Ramen V, Kinross J, Ziprin P: Robotic vs. laparoscopic Roux-en-Y gastric bypass in morbidly obese patients: systematic review and pooled analysis. The international journal of medical robotics + computer assisted surgery : MRCAS 2011, 7(4):393-400.

Li JV, Ashrafian H, Bueter M, Kinross J, Sands C, le Roux CW, Bloom SR, Darzi A, Athanasiou T, Marchesi JR et al: Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk. Gut 2011, 60(9):1214-1223.

Kinross JM, Holmes E, Darzi AW, Nicholson JK: Metabolic phenotyping for monitoring surgical patients. Lancet 2011, 377(9780):1817-1819.

Kinross JM, Darzi AW, Nicholson JK: Gut microbiome-host interactions in health and disease. Genome medicine 2011, 3(3):14.

Kinross JM, Alkhamesi N, Barton RH, Silk DB, Yap IK, Darzi AW, Holmes E, Nicholson JK: Global metabolic phenotyping in an experimental laparotomy model of surgical trauma. Journal of proteome research 2011, 10(1):277-287.

Patel V, Aggarwal R, Kinross J, Taylor D, Davies R, Darzi A: Improving informed consent of surgical patients using a multimedia-based program?: results of a prospective randomized multicenter study of patients before cholecystectomy. Annals of surgery 2009, 249(3):546-547; author reply 547-548.

Kinross J, Warren O, Basson S, Holmes E, Silk D, Darzi A, Nicholson JK: Intestinal ischemia/reperfusion injury: defining the role of the gut microbiome. Biomarkers in medicine 2009, 3(2):175-192.

Kinross J, von Roon AC, Penney N, Holmes E, Silk D, Nicholson JK, Darzi A: The gut microbiota as a target for improved surgical outcome and improved patient care. Current pharmaceutical design 2009, 15(13):1537-1545.

Leong JJ, Kinross J, Taylor D, Purkayastha S: Surgeons have held conferences in Second Life. Bmj 2008, 337:a683.

Kinross JM, von Roon AC, Holmes E, Darzi A, Nicholson JK: The human gut microbiome: implications for future health care. Current gastroenterology reports 2008, 10(4):396-403.

Warren O, Alexiou C, Massey R, Leff D, Purkayastha S, Kinross J, Darzi A, Athanasiou T: The effects of various leukocyte filtration strategies in cardiac surgery. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2007, 31(4):665-676.

Rekhraj S, Kinross J, Prabhudesai S, Darzi A, Ziprin P: Intraperitoneal chemotherapy as first-line treatment in the management of epithelial ovarian cancer. Mini reviews in medicinal chemistry 2007, 7(5):509-517.

Mangoush O, Purkayastha S, Haj-Yahia S, Kinross J, Hayward M, Bartolozzi F, Darzi A, Athanasiou T: Heparin-bonded circuits versus nonheparin-bonded circuits: an evaluation of their effect on clinical outcomes. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2007, 31(6):1058-1069.

Kinross J, Warren O, Silk D, Darzi A: Perioperative synbiotic treatment to prevent postoperative infectious complications in biliary cancer surgery: a randomized control trial. Annals of surgery 2007, 245(6):1000.

Warren O, Kinross J, Paraskeva P, Darzi A: Emergency laparoscopy--current best practice. World journal of emergency surgery : WJES 2006, 1:24.

Purkayastha S, Chow A, Athanasiou T, Cambaroudis A, Panesar S, Kinross J, Tekkis P, Darzi A: Does serum procalcitonin have a role in evaluating the severity of acute pancreatitis? A question revisited. World journal of surgery 2006, 30(9):1713-1721.

Kinross J, Warren O, Darzi A: ATLS versus ETC: time for a decision? Annals of emergency medicine 2006, 48(6):761-762.

Aziz O, Athanasiou T, Panesar SS, Massey-Patel R, Warren O, Kinross J, Purkayastha S, Casula R, Glenville B, Darzi A: Does minimally invasive vein harvesting technique affect the quality of the conduit for coronary revascularization? The Annals of thoracic surgery 2005, 80(6):2407-2414.

Collaborators

Guido Franzoso, M.D., Ph.D., Imperial College London, Inflammation and Signal Transduction in colorectal cancer, 2011 - 2014

Prof. O'Keefe, Pittsburgh School of medicine, Colorectal cancer, 2011

Dr. Tim Orchard, Imperial College, Inflammatory bowel disease, 2011

Dr. Tony Gordon, Imperial College, Sepsis, 2010

Prof. Glen Gibson, Reading food biosciences unit, Gut microbiome, 2007

Dr. Julian Marchesi, Cardiff School of Biosciences, Gut metagenomics

Research Student Supervision

Eng,D, Personalised diagnostics in inflammatory bowel disease

Mirnezami,R, Systems metabolism of colorectal cancer

Muirhead,L, Analysis of diathermy plumes by Mass Spectrometry in Surgery

Umrani,I, Using virtual worlds to enhance medical student training in the operating theatre.

Vernazza,J, Metabonomic profiling of secondary peritonitis