Summary
Honorary Lecturer (ISM)
AffIlIATION
Hepatobiliary and Pancreatic Surgery
Biosketch
Dr. Jayant Kumar is a dedicated surgeon and researcher with a focus on hepatobiliary & pancreatic surgery, complemented by his interest in kidney and liver transplants. He had the privilege of completing an ASTS-accredited multi-organ abdominal transplant fellowship at the University of Chicago, guided by the esteemed Prof John Fung.
Previously, Dr. Kumar received training in HPB and general surgery at Imperial College London and achieved board certification in general surgery. He is also honored to be a member of the respected Royal College of Surgeons Edinburgh.
Dr. Kumar's academic credentials are a testament to his unwavering commitment to advancing the field of hepatobiliary and pancreatic surgery. He proudly holds an MD certification, complemented by a Master's degree in Hepatobiliary and Pancreatic Surgery from the globally renowned Imperial College London. Under the esteemed guidance of Prof. Nagy Habib, renowned for the groundbreaking Habib-4X RF-based device facilitating bloodless liver resections, and Prof. Henri Bismuth, a trailblazer in liver transplantation, Dr. Kumar adeptly defended his thesis.
Dr. Kumar, in his continuous pursuit of excellence in the medical field, successfully completed his Ph.D. in Medicine from the esteemed University of Warwick. His scholarly work provided an in-depth exploration into the clinical ramifications and immuno-modulatory shifts ensuing from liver resection utilizing RF-based devices in liver cancer scenarios. Notably, his research illuminated the role of checkpoint inhibitors in early liver cancer. Within his Ph.D. thesis, Dr. Kumar meticulously delineated its prospective application as both neoadjuvant and adjuvant therapies for Hepatocellular Carcinoma in its nascent stages.
Dr. Kumar has consistently been recognized for his exemplary contributions to the field of medical sciences, as demonstrated by his receipt of the Best Investigator Award from the American College of Surgeons in 2015. His research endeavors extend to probing the potential and intricacies of normothermic perfusion in liver transplantation. During his tenure at Royal Free Hospital, London, he garnered comprehensive training in the Normothermic Perfusion of the liver and played a pivotal role as a primary team member.
His dedication to research has not only led to noteworthy publications but has also been lauded on international platforms. Dr. Kumar was honored with the Young Investigator Award at both the "Asia-Pacific Primary Liver Cancer Expert Meeting" in Seoul, South Korea, and the "Japanese Digestive Disease Week 2018" in Kobe, Japan. In a more recent testament to his expansive knowledge and proficiency, he achieved the 2nd Prize in a rigorous quiz contest held by the AST 2021 (American Society of Transplantation), competing against peers from various surgical and medical subspecialties.
Selected Publications
Journal Articles
Jayant K, Cotter TG, Reccia I, et al., 2023, Comparing High- and Low-Model for End-Stage Liver Disease Living-Donor Liver Transplantation to Determine Clinical Efficacy: A Systematic Review and Meta-Analysis (CHALICE Study), Journal of Clinical Medicine, Vol:12
Reccia I, Pai M, Kumar J, et al., 2023, Tumour Heterogeneity and the Consequent Practical Challenges in the Management of Gastroenteropancreatic Neuroendocrine Neoplasms, Cancers, Vol:15
Podda M, Pisanu A, Morello A, et al., 2022, Laparoscopic <i>versus</i> open colectomy for locally advanced T4 colonic cancer: meta-analysis of clinical and oncological outcomes, British Journal of Surgery, Vol:109, ISSN:0007-1323, Pages:319-331
Witkowski P, Philipson LH, Buse JB, et al., 2022, Islets Transplantation at a Crossroads-Need for Urgent Regulatory Update in the United States: Perspective Presented During the Scientific Sessions 2021 at the American Diabetes Association Congress, Frontiers in Endocrinology, Vol:12, ISSN:1664-2392
Bachul P, Generette GS, Perez-Gutierrez A, et al., 2021, 307.5: Modified Approach Allowed for Improved Islet Allotransplantation Into Pre-vascularized Sernova Cell PouchTM Device - Preliminary Results of the Phase I/II Clinical Trial at University of Chicago., Transplantation, Vol:105
Jayant K, Reccia I, Bachul PJ, et al., 2021, The impact of COVID-19 on kidney transplant recipients in pre-vaccination and delta strain era: a systematic review and meta-analysis, Journal of Clinical Medicine, Vol:10, ISSN:2077-0383, Pages:1-39
Podda M, Pellino G, Coccolini F, et al., 2021, Compliance with evidence-based clinical guidelines in the management of acute biliary pancreatitis: the MANCTRA-1 study protocol, Updates in Surgery, Vol:73, ISSN:2038-131X, Pages:1757-1765
Witkowski P, Barth RN, Japour A, et al., 2021, Regulatory updates are needed to prevent the commercialization of islet transplantation in the United States, American Journal of Transplantation, Vol:21, ISSN:1600-6135, Pages:2620-2622
Bachul PJ, Golab K, Basto L, et al., 2021, Post-Hoc Analysis of a Randomized, Double Blind, Prospective Study at the University of Chicago: Additional Standardizations of Trial Protocol are Needed to Evaluate the Effect of a CXCR1/2 Inhibitor in Islet Allotransplantation, Cell Transplantation, Vol:30, ISSN:0963-6897
Witkowski P, Philipson LH, Kaufman DB, et al., 2021, The demise of islet allotransplantation in the United States: A call for an urgent regulatory update, American Journal of Transplantation, Vol:21, ISSN:1600-6135, Pages:1365-1375
Jayant K, Reccia I, Virdis F, et al., 2021, COVID-19 in hospitalized liver transplant recipients: An early systematic review and meta-analysis, Clinical Transplantation, Vol:35, ISSN:0902-0063
Kumar J, Reccia I, Virdis F, et al., 2021, Belatacept in renal transplantation in comparison to tacrolimus and molecular understanding of resistance pattern: Meta-analysis and systematic review., World J Transplant, Vol:11, ISSN:2220-3230, Pages:70-86
Podda M, Pisanu A, Segalini E, et al., 2020, Emergency right colectomy: is there a role for minimally invasive surgery?-A systematic review and meta-analysis of short-term clinical outcomes, Annals of Laparoscopic and Endoscopic Surgery, Vol:5, ISSN:2518-6973
Kumar J, Habib NAGY, Huang KAI, et al., 2020, Immunological basis of genesis of hepatocellular carcinoma: unique challenges and potential opportunities through immunomodulation, Vaccines, Vol:8, ISSN:2076-393X
da Costa AC, Sodergren M, Jayant K, et al., 2020, Radiofrequency combined with immunomodulation for hepatocellular carcinoma: State of the art and innovations, World Journal of Gastroenterology, Vol:26, ISSN:1007-9327, Pages:2040-2048
Jayant K, Habib N, Huang KW, et al., 2020, Recent Advances: The Imbalance of Immune Cells and Cytokines in the Pathogenesis of Hepatocellular Carcinoma, Diagnostics, Vol:10
Machairas N, Lang H, Jayant K, et al., 2020, Intrahepatic cholangiocarcinoma: Limitations for resectability, current surgical concepts and future perspectives, European Journal of Surgical Oncology, Vol:46, ISSN:0748-7983, Pages:740-746
Podda M, Di Saverio S, Davies RJ, et al., 2020, Prophylactic intra-abdominal drainage following colorectal anastomoses. A systematic review and meta-analysis of randomized controlled trials, American Journal of Surgery, Vol:219, ISSN:0002-9610, Pages:164-174
Generette GS, Bachul PJ, Golab K, et al., 2020, En bloc liver and pancreas transplantation after total pancreatectomy with autologous islet transplantation., Eur J Transl Clin Med, Vol:3, Pages:11-17
Janikashvili N, Jayant K, Kikodze N, et al., 2019, Immunomodulatory changes following isolated RF ablation in colorectal liver metastases: a case report, Medicines, Vol:6, ISSN:2305-6320
Huang KW, Jayant K, Lee P-H, et al., 2019, Positive immuno-modulation following radiofrequency assisted liver resection in hepatocellular carcinoma, Journal of Clinical Medicine, Vol:8, ISSN:2077-0383
Virdis F, Reccia I, Di Saverio S, et al., 2019, Clinical outcomes of primary arterial embolization in severe hepatic trauma: A systematic review, Diagnostic and Interventional Imaging, Vol:100, ISSN:2211-5684, Pages:65-75
Reccia I, Kumar J, Habib N, et al., 2018, The use of radiofrequency ablation in pancreatic cancer in the midst of the dawn of immuno-oncology, Medical Oncology, Vol:35, ISSN:1357-0560
Kumar J, Reccia I, Virdis F, et al., 2018, Systematic review and meta-analysis on the impact of thrombolytic therapy in liver transplantation following donation after circulatory death, Journal of Clinical Medicine, Vol:7, ISSN:2077-0383
Jayant K, Sodergren MH, Reccia I, et al., 2018, A systematic review and meta-analysis comparing liver resection with the rf-based device habib (TM)-4x with the clamp-crush technique, Cancers, Vol:10, ISSN:2072-6694, Pages:1-17
Reccia I, Kumar J, Kusano T, et al., 2018, Radiofrequency-assisted liver resection: Technique and results, Surgical Oncology - Oxford, Vol:27, ISSN:0960-7404, Pages:415-420
Jayant K, Reccia I, Shapiro AMJ, 2018, Normothermic ex-vivo liver perfusion: where do we stand?, Expert Review of Gastroenterology & Hepatology, Vol:12, ISSN:1747-4124, Pages:1045-1058
Mazmishvili K, Jayant K, Janikashvili N, et al., 2018, Study to evaluate the immunomodulatory effects of radiofrequency ablation compared to surgical resection for liver cancer, Journal of Cancer, Vol:9, ISSN:1837-9664, Pages:3187-3195
Reccia I, Sodergren MH, Jayant K, et al., 2018, The journey of radiofrequency-assisted liver resection, Surgical Oncology - Oxford, Vol:27, ISSN:0960-7404, Pages:A16-A18
Kumar J, Reccia I, Virdis F, et al., 2018, The role of normothermic perfusion In liver transplant (TRaNsIT Study): a systematic review of preliminary studies, Hpb Surgery, Vol:2018, ISSN:0894-8569, Pages:1-38
Kumar J, Reccia I, Sodergren MH, et al., 2018, Radiofrequency assisted pancreaticoduodenectomy for palliative surgical resection of locally advanced pancreatic adenocarcinoma, Oncotarget, Vol:9, ISSN:1949-2553, Pages:15732-15739
Mizandari M, Kumar J, Pai M, et al., 2018, Interventional radiofrequency ablation: A promising therapeutic modality in the management of malignant biliary and pancreatic duct obstruction, Journal of Cancer, Vol:9, ISSN:1837-9664, Pages:629-637
Mudan S, Kumar J, Mafalda NC, et al., 2017, Case report on the role of radiofrequency-assisted spleen-preserving surgery for splenic metastasis in the era of check-point inhibitors, Medicine, Vol:96, ISSN:0025-7974, Pages:e9106-e9106
Huang K-W, Lee P-H, Kusano T, et al., 2017, Impact of cavitron ultrasonic surgical aspirator (CUSA) and bipolar radiofrequency device (Habib-4X) based hepatectomy for hepatocellular carcinoma on tumour recurrence and disease-free survival, Oncotarget, Vol:8, ISSN:1949-2553, Pages:93644-93654
Vavra P, Roman J, Zonca P, et al., 2017, Recent Development of Augmented Reality in Surgery: A Review, Journal of Healthcare Engineering, Vol:2017, ISSN:2040-2309
Mizandari M, Azrumelashvili T, Kumar J, et al., 2017, Percutaneous Image-Guided Pancreatic Duct Drainage: Technique, Results and Expected Benefits., Cardiovascular and Interventional Radiology, Vol:40, ISSN:0174-1551, Pages:1911-1920
Reccia I, Kumar J, Tomokazu K, et al., 2017, A systemic review on radiofrequency assisted laparoscopic liver resection: Challenges and window to excel, Surgical Oncology, Vol:26, ISSN:1879-3320, Pages:296-304
Kumar J, Julie BM, Sharma A, et al., 2017, Systematic Review on Role of Mammalian Target of Rapamycin Inhibitors as an Alternative to Calcineurin Inhibitors in Renal Transplant: Challenges and Window to Excel, Experimental and Clinical Transplantation, Vol:15, ISSN:1304-0855, Pages:241-252
Reccia I, Kumar J, Akladios C, et al., 2017, Non-alcoholic fatty liver disease: a sign of systemic disease, Metabolism-Clinical and Experimental, Vol:72, ISSN:0026-0495, Pages:94-108
Kumar J, Reccia I, Kusano T, et al., 2017, Systemic meta-analysis assessing the short term applicability of early conversion to mammalian target of rapamycin inhibitors in kidney transplant., World J Transplant, Vol:7, ISSN:2220-3230, Pages:144-151