Imperial College London

ProfessorJohnLindon

Faculty of MedicineDepartment of Surgery & Cancer

Senior Research Investigator
 
 
 
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Contact

 

+44 (0)20 7594 3194j.lindon Website

 
 
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Location

 

Office no. 362Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Summary

Research Interests:

Metabonomics, NMR spectroscopy, computational chemistry, multivariate statistics, drug metabolism, applications in biomedicine

  • Development of new NMR spectroscopic methods
  • Analysis of NMR spectra of biofluids in normal and abnormal situations
  • Magic-angle-spinning NMR of tissues 
  • Identification of xenobiotic metabolites
  • Applications of directly coupled HPLC-NMR and HPLC-NMR-MS
  • Multivariate statistical approaches in metabonomics
  • Prediction of xenobiotic metabolism
  • Reactive drug metabolites 

Publications

Journals

Dumas M-E, Domange C, Calderari S, et al., 2016, Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series, Genome Medicine, Vol:8, ISSN:1756-994X

Kaluarachchi MR, Boulangé CL, Garcia-Perez I, et al., 2016, Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers., Bioanalysis, Vol:8, Pages:2023-2043

Karaman I, Ferreira DLS, Boulange CL, et al., 2016, Workflow for Integrated Processing of Multicohort Untargeted H-1 NMR Metabolomics Data in Large-Scale Metabolic Epidemiology, Journal of Proteome Research, Vol:15, ISSN:1535-3893, Pages:4188-4194

Lewis MR, Pearce JTM, Spagou K, et al., 2016, Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping, Analytical Chemistry, Vol:88, ISSN:0003-2700, Pages:9004-9013

More Publications