Imperial College London


Faculty of MedicineDepartment of Surgery & Cancer

Senior Research Investigator



+44 (0)20 7594 3194j.lindon Website




Office no. 362Sir Alexander Fleming BuildingSouth Kensington Campus





Research Interests:

Metabonomics, NMR spectroscopy, computational chemistry, multivariate statistics, drug metabolism, applications in biomedicine

  • Development of new NMR spectroscopic methods
  • Analysis of NMR spectra of biofluids in normal and abnormal situations
  • Magic-angle-spinning NMR of tissues 
  • Identification of xenobiotic metabolites
  • Applications of directly coupled HPLC-NMR and HPLC-NMR-MS
  • Multivariate statistical approaches in metabonomics
  • Prediction of xenobiotic metabolism
  • Reactive drug metabolites 


Dumas ME, Domange C, Calderari S, et al., 2016, Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series., Genome Med, Vol:8

Kaluarachchi MR, Boulangé CL, Garcia-Perez I, et al., 2016, Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers., Bioanalysis, Vol:8, Pages:2023-2043

Karaman I, Ferreira DL, Boulangé CL, et al., 2016, Workflow for Integrated Processing of Multicohort Untargeted (1)H NMR Metabolomics Data in Large-Scale Metabolic Epidemiology., J Proteome Res

Lewis MR, Pearce JT, Spagou K, et al., 2016, Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping., Anal Chem, Vol:88, Pages:9004-9013

Hansen PE, Borisov EV, Lindon JC, 2015, Determination of the tautomeric equilibria of pyridoyl benzoyl beta-diketones in the liquid and solid state through the use of deuterium isotope effects on H-1 and C-13 NMR chemical shifts and spin coupling constants, Spectrochimica Acta Part A-molecular and Biomolecular Spectroscopy, Vol:136, ISSN:1386-1425, Pages:107-112

More Publications