Imperial College London

Emeritus ProfessorJohnMansfield

Faculty of Natural SciencesDepartment of Life Sciences

Emeritus Professor of Plant Pathology
 
 
 
//

Contact

 

+44 (0)20 7594 5394j.mansfield

 
 
//

Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

//

Summary

 

Publications

Publication Type
Year
to

163 results found

Rufián JS, Macho AP, Corry DS, Mansfield JW, Ruiz-Albert J, Arnold DL, Beuzón CRet al., 2017, Confocal microscopy reveals in planta dynamic interactions between pathogenic, avirulent and non-pathogenic Pseudomonas syringae strains., Mol Plant Pathol

Recent advances in genomics and single-cell analysis have demonstrated the extraordinary complexity reached by microbial populations within their hosts. Communities range from complex multispecies groups to homogeneous populations differentiating into lineages through genetic or non-genetic mechanisms. Diversity within bacterial populations is recognized as a key driver of the evolution of animal pathogens. In plants, however, little is known about how interactions between different pathogenic and non-pathogenic variants within the host impact on defence responses, or how the presence within a mixture may affect the development or the fate of each variant. Using confocal fluorescence microscopy, we analysed the colonization of the plant apoplast by individual virulence variants of Pseudomonas syringae within mixed populations. We found that non-pathogenic variants can proliferate and even spread beyond the inoculated area to neighbouring tissues when in close proximity to pathogenic bacteria. The high bacterial concentrations reached at natural entry points promote such interactions during the infection process. We also found that a diversity of interactions take place at a cellular level between virulent and avirulent variants, ranging from dominant negative effects on proliferation of virulent bacteria to in trans suppression of defences triggered by avirulent bacteria. Our results illustrate the spatial dynamics and complexity of the interactions found within mixed infections, and their potential impact on pathogen evolution.

JOURNAL ARTICLE

Rufian JS, Sanchez-Romero M-A, Lopez-Marquez D, Macho AP, Mansfield JW, Arnold DL, Ruiz-Albert J, Casadesus J, Beuzon CRet al., 2016, Pseudomonas syringae differentiates into phenotypically distinct subpopulations during colonization of a plant host, ENVIRONMENTAL MICROBIOLOGY, Vol: 18, Pages: 3593-3605, ISSN: 1462-2912

JOURNAL ARTICLE

Stewart SA, Hodge S, Bennett M, Mansfield JW, Powell Get al., 2016, Aphid induction of phytohormones in Medicago truncatula is dependent upon time post-infestation, aphid density and the genotypes of both plant and insect, ARTHROPOD-PLANT INTERACTIONS, Vol: 10, Pages: 41-53, ISSN: 1872-8855

JOURNAL ARTICLE

Wye with Hinxhill Parish Council, 2016, Wye Neighbourhood Development Plan, Ashford Borough Council

OTHER

Li B, Hulin MT, Brain P, Mansfield JW, Jackson RW, Harrison RJet al., 2015, Rapid, automated detection of stem canker symptoms in woody perennials using artificial neural network analysis, PLANT METHODS, Vol: 11, ISSN: 1746-4811

JOURNAL ARTICLE

Mitchell K, Brown I, Knox P, Mansfield Jet al., 2015, The role of cell wall-based defences in the early restriction of non-pathogenic hrp mutant bacteria in Arabidopsis, PHYTOCHEMISTRY, Vol: 112, Pages: 139-150, ISSN: 0031-9422

JOURNAL ARTICLE

Zabala MDT, Littlejohn G, Jayaraman S, Studholme D, Bailey T, Lawson T, Tillich M, Licht D, Boelter B, Delfino L, Truman W, Mansfield J, Smirnoff N, Grant Met al., 2015, Chloroplasts play a central role in plant defence and are targeted by pathogen effectors, NATURE PLANTS, Vol: 1, ISSN: 2055-026X

JOURNAL ARTICLE

Hodge S, Ward JL, Beale MH, Bennett M, Mansfield JW, Powell Get al., 2013, Aphid-induced accumulation of trehalose in Arabidopsis thaliana is systemic and dependent upon aphid density, PLANTA, Vol: 237, Pages: 1057-1064, ISSN: 0032-0935

JOURNAL ARTICLE

Mansfield J, Genin S, Magori S, Citovsky V, Sriariyanum M, Ronald P, Dow M, Verdier V, Beer SV, Machado MA, Toth I, Salmond G, Foster GDet al., 2012, Top 10 plant pathogenic bacteria in molecular plant pathology, MOLECULAR PLANT PATHOLOGY, Vol: 13, Pages: 614-629, ISSN: 1464-6722

JOURNAL ARTICLE

Pham J, Liu J, Bennett MH, Mansfield JW, Desikan Ret al., 2012, Arabidopsis histidine kinase 5 regulates salt sensitivity and resistance against bacterial and fungal infection, NEW PHYTOLOGIST, Vol: 194, Pages: 168-180, ISSN: 0028-646X

JOURNAL ARTICLE

Arnold DL, Lovell HC, Jackson RW, Mansfield JWet al., 2011, Pseudomonas syringae pv. phaseolicola: from 'has bean' to supermodel, MOLECULAR PLANT PATHOLOGY, Vol: 12, Pages: 617-627, ISSN: 1464-6722

JOURNAL ARTICLE

Denness L, McKenna JF, Segonzac C, Wormit A, Madhou P, Bennett M, Mansfield J, Zipfel C, Hamann Tet al., 2011, Cell Wall Damage-Induced Lignin Biosynthesis Is Regulated by a Reactive Oxygen Species- and Jasmonic Acid-Dependent Process in Arabidopsis, PLANT PHYSIOLOGY, Vol: 156, Pages: 1364-1374, ISSN: 0032-0889

JOURNAL ARTICLE

Godfrey SAC, Lovell HC, Mansfield JW, Corry DS, Jackson RW, Arnold DLet al., 2011, The Stealth Episome: Suppression of Gene Expression on the Excised Genomic Island PPHGI-1 from Pseudomonas syringae pv. phaseolicola, PLOS PATHOGENS, Vol: 7, ISSN: 1553-7374

JOURNAL ARTICLE

Lovell HC, Jackson RW, Mansfield JW, Godfrey SAC, Hancock JT, Desikan R, Arnold DLet al., 2011, In planta conditions induce genomic changes in Pseudomonas syringae pv. phaseolicola, MOLECULAR PLANT PATHOLOGY, Vol: 12, Pages: 167-176, ISSN: 1464-6722

JOURNAL ARTICLE

Forcat S, Bennett M, Grant M, Mansfield JWet al., 2010, Rapid linkage of indole carboxylic acid to the plant cell wall identified as a component of basal defence in Arabidopsis against hrp mutant bacteria, PHYTOCHEMISTRY, Vol: 71, Pages: 870-876, ISSN: 0031-9422

JOURNAL ARTICLE

Forsyth A, Mansfield JW, Grabov N, de Torres M, Sinapidou E, Grant MRet al., 2010, Genetic Dissection of Basal Resistance to Pseudomonas syringae pv. phaseolicola in Accessions of Arabidopsis, MOLECULAR PLANT-MICROBE INTERACTIONS, Vol: 23, Pages: 1545-1552, ISSN: 0894-0282

JOURNAL ARTICLE

Godfrey SAC, Mansfield JW, Corry DS, Lovell HC, Jackson RW, Arnold DLet al., 2010, Confocal Imaging of Pseudomonas syringae pv. phaseolicola Colony Development in Bean Reveals Reduced Multiplication of Strains Containing the Genomic Island PPHGI-1, MOLECULAR PLANT-MICROBE INTERACTIONS, Vol: 23, Pages: 1294-1302, ISSN: 0894-0282

JOURNAL ARTICLE

Mansfield J, 2010, New Honorary Member of BSPP, PLANT PATHOLOGY, Vol: 59, Pages: 1-2, ISSN: 0032-0862

JOURNAL ARTICLE

Ortiz-Martin I, Thwaites R, Macho AP, Mansfield JW, Beuzon CRet al., 2010, Positive Regulation of the Hrp Type III Secretion System in Pseudomonas syringae pv. phaseolicola, MOLECULAR PLANT-MICROBE INTERACTIONS, Vol: 23, Pages: 665-681, ISSN: 0894-0282

JOURNAL ARTICLE

Ortiz-Martin I, Thwaites R, Mansfield JW, Beuzon CRet al., 2010, Negative Regulation of the Hrp Type III Secretion System in Pseudomonas syringae pv. phaseolicola, MOLECULAR PLANT-MICROBE INTERACTIONS, Vol: 23, Pages: 682-701, ISSN: 0894-0282

JOURNAL ARTICLE

Ward JL, Forcat S, Beckmann M, Bennett M, Miller SJ, Baker JM, Hawkins ND, Vermeer CP, Lu C, Lin W, Truman WM, Beale MH, Draper J, Mansfield JW, Grant Met al., 2010, The metabolic transition during disease following infection of Arabidopsis thaliana by Pseudomonas syringae pv. tomato, PLANT JOURNAL, Vol: 63, Pages: 443-457, ISSN: 0960-7412

JOURNAL ARTICLE

Hamann T, Bennett M, Mansfield J, Somerville Cet al., 2009, Identification of cell-wall stress as a hexose-dependent and osmosensitive regulator of plant responses, PLANT JOURNAL, Vol: 57, Pages: 1015-1026, ISSN: 0960-7412

JOURNAL ARTICLE

Lovell HC, Mansfield JW, Godfrey SAC, Jackson RW, Hancock JT, Arnold DLet al., 2009, Bacterial Evolution by Genomic Island Transfer Occurs via DNA Transformation In Planta, CURRENT BIOLOGY, Vol: 19, Pages: 1586-1590, ISSN: 0960-9822

JOURNAL ARTICLE

Mansfield JW, 2009, From bacterial avirulence genes to effector functions via the hrp delivery system: an overview of 25 years of progress in our understanding of plant innate immunity, MOLECULAR PLANT PATHOLOGY, Vol: 10, Pages: 721-734, ISSN: 1464-6722

JOURNAL ARTICLE

Stewart SA, Hodge S, Ismail N, Mansfield JW, Feys BJ, Prosperi J-M, Huguet T, Ben C, Gentzbittel L, Powell Get al., 2009, The RAP1 Gene Confers Effective, Race-Specific Resistance to the Pea Aphid in Medicago truncatula Independent of the Hypersensitive Reaction, MOLECULAR PLANT-MICROBE INTERACTIONS, Vol: 22, Pages: 1645-1655, ISSN: 0894-0282

JOURNAL ARTICLE

Forcat S, Bennett MH, Mansfield JW, Grant MRet al., 2008, A rapid and robust method for simultaneously measuring changes in the phytohormones ABA, JA and SA in plants following biotic and abiotic stress, PLANT METHODS, Vol: 4, ISSN: 1746-4811

JOURNAL ARTICLE

Goehre V, Spallek T, Haeweker H, Mersmann S, Mentzel T, Boller T, de Torres M, Mansfield JW, Robatzek Set al., 2008, Plant Pattern-Recognition Receptor FLS2 Is Directed for Degradation by the Bacterial Ubiquitin Ligase AvrPtoB, CURRENT BIOLOGY, Vol: 18, Pages: 1824-1832, ISSN: 0960-9822

JOURNAL ARTICLE

Tsiamis G, Siozios S, Mansfield J, Bourtzis Ket al., 2008, Expression of the HrpA gene product in planta activates plant immunity in Arabidopsis thaliana, Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Publisher: BLACKWELL PUBLISHING, Pages: 276-276, ISSN: 1742-464X

CONFERENCE PAPER

Wang G, Ellendorff U, Kemp B, Mansfield JW, Forsyth A, Mitchell K, Bastas K, Liu C-M, Woods-Toer A, Zipfel C, de Wit PJGM, Jones JDG, Toer M, Thomma BPHJet al., 2008, A genome-wide functional investigation into the roles of receptor-like proteins in Arabidopsis, PLANT PHYSIOLOGY, Vol: 147, Pages: 503-517, ISSN: 0032-0889

JOURNAL ARTICLE

Arnold DL, Jackson RW, Waterfield NR, Mansfield JWet al., 2007, Evolution of microbial virulence: the benefits of stress, TRENDS IN GENETICS, Vol: 23, Pages: 293-300, ISSN: 0168-9525

JOURNAL ARTICLE

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: respub-action=search.html&id=00309283&limit=30&person=true