Imperial College London
Alternate

Emeritus ProfessorJohnWarner

Faculty of Medicine, National Heart & Lung Institute

Emeritus in Paediatrics
 
 
 
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Contact

 

j.o.warner

 
 
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Location

 

246Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@inbook{Spergel:2016:10.1016/B978-0-12-420226-9.00018-8,
author = {Spergel, JM and Warner, JO},
booktitle = {Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March},
doi = {10.1016/B978-0-12-420226-9.00018-8},
pages = {303--319},
title = {Pharmacotherapies Early in Life to Prevent the Atopic March},
url = {http://dx.doi.org/10.1016/B978-0-12-420226-9.00018-8},
year = {2016}
}
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RIS format (EndNote, RefMan)

TY  - CHAP
AB  - The progression of atopic dermatitis to asthma is considered part of the atopic march. Various strategies have been examined to prevent this progression. In related diseases such as inflammatory bowel disease, disease-modifying agents exist and affect the natural history of disease. These agents can be broken down into three broad classes: primary, secondary, and tertiary agents. Primary strategies have preliminary success in preventing atopic dermatitis with barrier creams, but additional longitudinal studies are needed to see whether the benefit is maintained. Secondary strategies using antihistamines, topical medications for atopic dermatitis or asthma, have not been able to prevent the progression of atopic dermatitis to asthma or change the natural history of asthma. However, specific immunotherapy has shown benefit in one well-designed study. Tertiary prevention agents that help with symptom and disease flare-ups are successful with the use of maintenance medications for asthma or atopic dermatitis. Additional studies are needed to find the optimal method to prevent development of the atopic march.
AU  - Spergel,JM
AU  - Warner,JO
DO  - 10.1016/B978-0-12-420226-9.00018-8
EP  - 319
PY  - 2016///
SN  - 9780124202269
SP  - 303
TI  - Pharmacotherapies Early in Life to Prevent the Atopic March
T1  - Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March
UR  - http://dx.doi.org/10.1016/B978-0-12-420226-9.00018-8
ER  -
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