Imperial College London
Alternate

Emeritus ProfessorJohnWarner

Faculty of Medicine, National Heart & Lung Institute

Emeritus in Paediatrics
 
 
 
//

Contact

 

j.o.warner

 
 
//

Location

 

246Medical SchoolSt Mary's Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Levin:2017,
author = {Levin, ME and Warner, JO},
journal = {Current Allergy and Clinical Immunology},
pages = {150--154},
title = {The atopic dance},
url = {http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000412709400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202},
volume = {30},
year = {2017}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - The atopic march refers to the disorders that commonly occur together and track with age in a characteristic order, starting with atopic dermatitis often associated with food allergy, then inhalant allergy contributing to the development of asthma and then rhinitis. The implication of this model of the allergic march is that there is a linear progression from one manifestation to another, and a further assumption that there is a single predominant mechanism (of ‘atopy’ which may be defined as the susceptibility to becoming allergic) behind all the manifestations. New insights from the advent of molecular medicine indicate that many allergic diseases are better seen as syndromes comprising multiple phenotypes, with different gene/environment interactions and consequent endotypes. In addition, there are multiple contributing aetiologies to each ‘syndrome’ and complicated interactions between them are better visualised as causal networks, rather than as linear cause and effect. These factors and the variability of progression from one form of atopy to another are at odds with the concept of the ‘atopic march’. We, therefore, suggest that the ‘Atopic March’ is an outdated concept which might be better considered as an ‘Atopic Tango’.
AU  - Levin,ME
AU  - Warner,JO
EP  - 154
PY  - 2017///
SN  - 1609-3607
SP  - 150
TI  - The atopic dance
T2  - Current Allergy and Clinical Immunology
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000412709400004&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://journals.co.za/content/journal/10520/EJC-c3c88dbd9
UR  - http://hdl.handle.net/10044/1/71344
VL  - 30
ER  -
Download