Publications
190 results found
Walker MM, Negus R, Rice AJ, et al., 2000, Are all five sites of the Sydney system essential to assess <i>H-pylori</i> and gastritis?, GUT, Vol: 47, Pages: A57-A57, ISSN: 0017-5749
Walker MM, Teare JP, Negus R, et al., 2000, Are all five biopsy sites of the updated Sydney system essential to assess gastritis?, GASTROENTEROLOGY, Vol: 118, Pages: A1320-A1320, ISSN: 0016-5085
Gummett P, Walker MM, Loh V, et al., 1998, Advantages of near patient testing for <i>H-pylori</i> using infrared isotope analysis., GASTROENTEROLOGY, Vol: 114, Pages: A141-A141, ISSN: 0016-5085
Gummett P, Walker MM, Loh V, et al., 1998, Advantages of near patient testing for <i>H-pylori</i> using infra-red isotope analysis, GUT, Vol: 42, Pages: A81-A81, ISSN: 0017-5749
Lloyd J, Darzi A, Teare J, et al., 1997, A solitary benign lymphoid polyp of the rectum in a 51 year old woman, JOURNAL OF CLINICAL PATHOLOGY, Vol: 50, Pages: 1034-1035, ISSN: 0021-9746
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- Citations: 9
Teare JP, Daly CA, Rodgers C, et al., 1997, Pancreatic abnormalities and AIDS related sclerosing cholangitis, Genitourinary Medicine, Vol: 73, Pages: 271-273, ISSN: 0266-4348
Objectives: Biliary tract abnormalities are well recognised in AIDS, most frequently related to opportunistic infection with Cryptosporidium, Microsporidium, and cytomegalovirus. We noted a high frequency of pancreatic abnormalities associated with biliary tract disease. To define these further we reviewed the clinical and radiological features in these patients. Methods: Notes and radiographs were available from two centres for 83 HIV positive patients who had undergone endoscopic retrograde cholangiopancreatography for the investigation of cholestatic liver function tests or abdominal pain. Results: 56 patients had AIDS related sclerosing cholangitis (ARSC); 86% of these patients had epigastric or right upper quadrant pain and 52% had hepatomegaly. Of the patients with ARSC, 10 had papillary stenosis alone, 11 had intra- and extrahepatic sclerosing cholangitis alone, and 35 had a combination of the two. Ampullary biopsies performed in 24 patients confirmed an opportunistic infection in 16. In 15 patients, intraluminal polyps were noted on the cholangiogram. Pancreatograms were available in 34 of the 45 patients with papillary stenosis, in which 29 (81%) had associated pancreatic duct dilatation, often with associated features of chronic pancreatitis. In the remaining 27 patients, final diagnoses included drug induced liver disease, acalculous cholecystitis, gall bladder empyema, chronic B virus hepatitis, and alcoholic liver disease. Conclusion. Pancreatic abnormalities are commonly seen with ARSC and may be responsible for some of the pain not relieved by biliary sphincterotomy. The most frequent radiographic biliary abnormality is papillary stenosis combined with ductal sclerosis.
Thursz M, Mantafounis D, Yallop R, et al., 1997, Severe alcoholic liver disease is associated with the haemochromatosis gene mutant, GASTROENTEROLOGY, Vol: 112, Pages: A1401-A1401, ISSN: 0016-5085
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- Citations: 5
Teare JP, Beveridge IG, Sumiya M, et al., 1997, Cytochrome p450IIE1 polymorphism predisposes to alcoholic cirrhosis, GASTROENTEROLOGY, Vol: 112, Pages: A1398-A1398, ISSN: 0016-5085
Teare JP, Daly CA, Rodgers C, et al., 1997, Pancreatic abnormalities and AIDS related sclerosing cholangitis., Genitourinary …
GARIOCH JJ, BAKER BS, TEARE J, et al., 1995, AN IMMUNOHISTOCHEMICAL STUDY OF INTERFERON-GAMMA, INTERLEUKIN-2 AND INTERLEUKIN-4 IN THE SMALL-INTESTINE OF PATIENTS WITH DERMATITIS-HERPETIFORMIS, JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol: 105, Pages: 515-515, ISSN: 0022-202X
TEARE JP, PRICE DA, FOSTER GR, et al., 1995, REVERSIBLE AIDS-RELATED SCLEROSING CHOLANGITIS, JOURNAL OF HEPATOLOGY, Vol: 23, Pages: 209-211, ISSN: 0169-5185
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- Citations: 5
MARWAY JS, HEAP L, TEARE J, et al., 1995, ANTIOXIDANT STATUS IN THE JEJUNUM - EFFECT OF ACUTE ETHANOL DOSAGE, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 23, Pages: S463-S463, ISSN: 0300-5127
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- Citations: 1
TEARE JP, SPEDDING C, WHITEHEAD MW, et al., 1995, OMEPRAZOLE AND DRY MOUTH, SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, Vol: 30, Pages: 216-218, ISSN: 0036-5521
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- Citations: 41
TEARE JP, BOOTH JCL, BROWN JL, et al., 1995, PSEUDOMEMBRANOUS COLITIS FOLLOWING CLARITHROMYCIN THERAPY, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, Vol: 7, Pages: 275-277, ISSN: 0954-691X
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- Citations: 34
PUNCHARD NA, SENTURK H, TEARE JP, et al., 1994, RESISTANCE OF ERYTHROCYTES TO LIPID-PEROXIDATION IN ALCOHOLIC PATIENTS, GUT, Vol: 35, Pages: 1753-1756, ISSN: 0017-5749
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- Citations: 11
TEARE JP, GREENFIELD SM, WATSON D, et al., 1994, LIPID-PEROXIDATION IN RATS CHRONICALLY FED ETHANOL, GUT, Vol: 35, Pages: 1644-1647, ISSN: 0017-5749
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- Citations: 32
TEARE JP, WATKINSON AF, ERB SR, et al., 1994, TRANSFEMORAL LIVER-BIOPSY BY FORCEPS - A REVIEW OF 104 CONSECUTIVE PROCEDURES, CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY, Vol: 17, Pages: 252-257, ISSN: 0174-1551
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- Citations: 10
SHORI DK, PROCTOR GB, TEARE J, et al., 1994, INDEXES OF PROTEIN-SYNTHESIS AND RNA TRANSLATING ACTIVITIES IN THE MAJOR SALIVARY-GLANDS OF RAT AND COMPARISON TO SYNTHETIC RATES IN LIVER, BIOCHEMICAL SOCIETY TRANSACTIONS, Vol: 22, Pages: S182-S182, ISSN: 0300-5127
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- Citations: 3
SCUDAMORE CH, HEMMING AW, TEARE JP, et al., 1994, SURGICAL-MANAGEMENT OF CHOLEDOCHAL CYSTS, AMERICAN JOURNAL OF SURGERY, Vol: 167, Pages: 497-500, ISSN: 0002-9610
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- Citations: 42
PUNCHARD NA, WATSON DJ, TEARE JP, et al., 1994, EFFECTS OF ALCOHOL ON GASTRIC PROSTAGLANDIN PRODUCTION AND GLUTATHIONE STATUS, 649th Meeting of the Biochemical-Society, Publisher: PORTLAND PRESS, Pages: S196-S196, ISSN: 0300-5127
Punchard NA, Watson DJ, Teare JP, et al., 1994, Effects of alcohol on gastric prostaglandin production and glutathione status., Biochem Soc Trans, Vol: 22, ISSN: 0300-5127
TEARE JP, GREENFIELD SM, WHITEHEAD MW, et al., 1994, A RAT MODEL OF ALCOHOLIC HEPATITIS AND FIBROSIS, GASTROENTEROLOGY, Vol: 106, Pages: A997-A997, ISSN: 0016-5085
TEARE JP, SHERMAN D, GREENFIELD SM, et al., 1993, COMPARISON OF SERUM PROCOLLAGEN-III PEPTIDE CONCENTRATIONS AND PGA INDEX FOR ASSESSMENT OF HEPATIC-FIBROSIS, LANCET, Vol: 342, Pages: 895-898, ISSN: 0140-6736
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- Citations: 93
Greenfield SM, Punchard NA, Teare JP, et al., 1993, Review article: the mode of action of the aminosalicylates in inflammatory bowel disease., Aliment Pharmacol Ther, Vol: 7, Pages: 369-383, ISSN: 0269-2813
Sulphasalazine and other 5-aminosalicylic acid (5-ASA)-containing drugs are used in the treatment of acute inflammatory bowel disease and in the maintenance of clinical remission. Despite their use for over 50 years, the mechanism of action of this class of drugs remains uncertain, although a number of possibilities are discussed in this review. It seems likely that the aminosalicylates are important free radical scavengers, can reduce leukotriene production and can inhibit the cellular release of interleukin-1, all of which are likely to be important in reducing the acute inflammatory response in inflammatory bowel disease. The effects of these drugs on prostaglandin production are more contentious, but it appears that 10(-5) to 10(-4) M concentrations stimulate production of prostaglandins which may be cytoprotective, while higher doses of these drugs inhibit prostaglandin production. The aminosalicylates may maintain remission in inflammatory bowel disease by preventing leucocyte recruitment into the bowel wall. The drugs inhibit the chemotactic response to leukotriene B4, reduce the synthesis of platelet activating factor and also inhibit leucocyte adhesion molecule upregulation.
GREENFIELD SM, PUNCHARD NA, TEARE JP, et al., 1993, THE MODE OF ACTION OF THE AMINOSALICYLATES IN INFLAMMATORY BOWEL-DISEASE, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Vol: 7, Pages: 369-383, ISSN: 0269-2813
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- Citations: 122
GREENFIELD SM, TEARE JP, WHITEHEAD MW, et al., 1993, AMAUROSIS FUGAX, CROHNS-DISEASE AND THE ANTICARDIOLIPIN ANTIBODY, LUPUS, Vol: 2, Pages: 271-273, ISSN: 0961-2033
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- Citations: 14
TEARE JP, GREENFIELD SM, MARWAY JS, et al., 1993, EFFECT OF THYROIDECTOMY AND ADRENALECTOMY ON CHANGES IN LIVER GLUTATHIONE AND MALONALDEHYDE LEVELS AFTER ACUTE ETHANOL INJECTION, FREE RADICAL BIOLOGY AND MEDICINE, Vol: 14, Pages: 655-660, ISSN: 0891-5849
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- Citations: 9
GREENFIELD SM, GREEN AT, TEARE JP, et al., 1993, A RANDOMIZED CONTROLLED-STUDY OF EVENING PRIMROSE OIL AND FISH OIL IN ULCERATIVE-COLITIS, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Vol: 7, Pages: 159-166, ISSN: 0269-2813
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- Citations: 85
TEARE JP, PUNCHARD NA, POWELL JJ, et al., 1993, AUTOMATED SPECTROPHOTOMETRIC METHOD FOR DETERMINING OXIDIZED AND REDUCED GLUTATHIONE IN LIVER, CLINICAL CHEMISTRY, Vol: 39, Pages: 686-689, ISSN: 0009-9147
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- Citations: 58
SIDDIQ T, RICHARDSON PJ, MITCHELL WD, et al., 1993, ETHANOL-INDUCED INHIBITION OF VENTRICULAR PROTEIN-SYNTHESIS INVIVO AND THE POSSIBLE ROLE OF ACETALDEHYDE, CELL BIOCHEMISTRY AND FUNCTION, Vol: 11, Pages: 45-54, ISSN: 0263-6484
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- Citations: 45
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