Imperial College London

Professor Julian Teare

Faculty of MedicineDepartment of Surgery & Cancer

Emeritus Professor
 
 
 
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Contact

 

+44 (0)20 3312 1072j.teare

 
 
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Location

 

CL3 026St Marys Multiple BuildingsSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Glover:2020:10.1055/a-0999-5252,
author = {Glover, B and Teare, J and Patel, N},
doi = {10.1055/a-0999-5252},
journal = {Endoscopy International Open},
pages = {E105--E114},
title = {A systematic review of the role of non-magnified endoscopy for the assessment of H. pylori infection.},
url = {http://dx.doi.org/10.1055/a-0999-5252},
volume = {8},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundThere is growing interest in the endoscopic recognition of H. pylori infection, and application to routine practice. We present a systematic review of the current literature regarding diagnosis of H. pylori during standard (non-magnified) endoscopy, including adjuncts such as image enhancement and computer-aided diagnosis.MethodThe Medline and Cochrane databases were searched for studies investigating the performance of non-magnified optical diagnosis for H. pylori, or those which characterised mucosal features associated with H. pylori infection. Studies were preferred with a validated reference test as the comparator, although were included if at least one validated reference test was used.Results20 suitable studies were identified and included for analysis. In total, 4,703 patients underwent investigation including white light endoscopy, narrow band imaging, i-scan, blue-laser imaging, and computer-aided diagnostic techniques. The endoscopic features of H. pylori infection observed using each modality are discussed and diagnostic accuracies reported. The Regular Arrangement of Collecting Venules (RAC) is an important predictor of the H. pylori naïve stomach. ‘Mosaic’ and ‘Mottled’ patterns have a positive association with H. pylori infection. The ‘Cracked’ pattern may be a predictor of an H. pylori negative stomach following eradication.ConclusionsThis review summarises the current progress made in endoscopic diagnosis of H. pylori infection. At present there is no single diagnostic approach that provides validated diagnostic accuracy. Further prospective studies are required, as is the development of a validated classification system. Early studies in Computer-Aided Diagnosis suggest potential for a high level of accuracy but real-time results are awaited.
AU - Glover,B
AU - Teare,J
AU - Patel,N
DO - 10.1055/a-0999-5252
EP - 114
PY - 2020///
SN - 2196-9736
SP - 105
TI - A systematic review of the role of non-magnified endoscopy for the assessment of H. pylori infection.
T2 - Endoscopy International Open
UR - http://dx.doi.org/10.1055/a-0999-5252
UR - https://www.thieme-connect.de/products/ejournals/abstract/10.1055/a-0999-5252
UR - http://hdl.handle.net/10044/1/71601
VL - 8
ER -