Publications
321 results found
Weber JN, Fenyo EM, 2002, WHO-UNAIDS Guidelines for Standard HIV Isolation and Characterisation Procedures, ISBN: 9789241590211
Oxenius A, Fidler S, Brady M, et al., 2001, Variable fate of virus-specific CD4<SUP>+</SUP> T cells during primary HIV-1 infection, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 31, Pages: 3782-3788, ISSN: 0014-2980
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- Citations: 29
Rowland-Jones SL, Pinheiro S, Kaul R, et al., 2001, How important is the 'quality' of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection?, IMMUNOLOGY LETTERS, Vol: 79, Pages: 15-20, ISSN: 0165-2478
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- Citations: 61
Smith D, Gow I, Colebunders R, et al., 2001, Therapeutic vaccination (p24-VLP) of patients with advanced HIV-1 infection in the pre-HAART era does not alter CD4 cell decline., HIV Med, Vol: 2, Pages: 272-275, ISSN: 1464-2662
In a randomized placebo controlled trial 304 HIV infected patients with CD4 cell counts below 350 cells/microL received therapeutic vaccination with: alum placebo (Group I, n = 102), p24-VLP 500 microg (Group II, n = 101) or p24-VLP 1000 microg (Group III, n = 101) p24-VLP monthly for six months. Over one year the average change in CD4 cell count did not differ significantly between groups (-32, -40 and -52 cells per microL respectively). There was also no difference between groups in progression to CDC category B or C events, or in adverse events. Therapeutic vaccination with p24-VLP does not affect CD4 cell decline in patients with advanced HIV infection.
Bobkov AF, Samokhvalov EI, Lvov DK, et al., 2001, Absence of viral transmission in injecting drug users in Russia, LANCET, Vol: 358, Pages: 1016-1017, ISSN: 0140-6736
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- Citations: 7
Fidler S, Frater J, Clarke J, et al., 2001, HIV-1 drug resistance in primary infections in the UK, BRITISH MEDICAL JOURNAL, Vol: 323, Pages: 632-633, ISSN: 0959-535X
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- Citations: 9
Weber J, Nunn A, O'Conner T, et al., 2001, 'Chemical condoms' for the prevention of HIV infection:: evaluation of novel agents against SHIV<sub>89.6PD</sub> <i>in vitro</i> and <i>in vivo</i>, AIDS, Vol: 15, Pages: 1563-1568, ISSN: 0269-9370
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- Citations: 77
Frater AJ, Beardall A, Ariyoshi K, et al., 2001, Impact of baseline polymorphisms in <i>RT</i> and <i>protease</i> on outcome of highly active antiretroviral therapy in HIV-1-infected African patients, AIDS, Vol: 15, Pages: 1493-1502, ISSN: 0269-9370
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- Citations: 78
Hanon E, Goon P, Taylor GP, et al., 2001, High production of interferon γ but not interleukin-2 by human T-lymphotropic virus type I-infected peripheral blood mononuclear cells, BLOOD, Vol: 98, Pages: 721-726, ISSN: 0006-4971
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- Citations: 74
Oxenius A, Günthard HF, Hirschel B, et al., 2001, Direct <i>ex vivo</i> analysis reveals distinct phenotypic patterns of HIV-specific CD<SUP>8+</SUP> T lymphocyte activation in response to therapeutic manipulation of virus load, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 31, Pages: 1115-1121, ISSN: 0014-2980
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- Citations: 24
Frater AJ, Chaput CC, Beddows S, et al., 2001, Simple detection of point mutations associated with HIV-1 drug resistance, JOURNAL OF VIROLOGICAL METHODS, Vol: 93, Pages: 145-156, ISSN: 0166-0934
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- Citations: 9
Churchill DR, Slade PM, Youle M, et al., 2001, A phase I/II study of the safety and activity of a microsphere formulation of KNI-272 in patients with HIV-1 infection., J Antimicrob Chemother, Vol: 47, Pages: 353-355, ISSN: 0305-7453
Eighteen patients with symptomatic HIV disease were enrolled into a phase I/II study of a microsphere formulation of the HIV protease inhibitor KNI-272, with doses escalated up to a maximum dose of 60 mg/kg/day. One patient developed reversible elevation in hepatic transaminase. The plasma half-life of the drug was very short, varying between 0.25 and 1.1 h. No consistent effect on plasma HIV RNA levels or CD4(+) lymphocyte counts was seen.
Weber JN, Lacey CJN, 2001, The development of novel vaginal microbicides: from the bench to the clinic., AIDS, Vol: 15, Pages: S35-S37, ISSN: 0269-9370
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- Citations: 3
Bobkov A, Kazennova E, Khanina T, et al., 2001, An HIV type 1 subtype a strain of low genetic diversity continues to spread among injecting drug users in Russia: study of the new local outbreaks in Moscow and Irkutsk, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 17, Pages: 257-261, ISSN: 0889-2229
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- Citations: 48
Lacey CJN, Kitchen VS, Rosenstein I, et al., 2001, Are there critical endpoints in phase I/II trials of vaginal microbicides? A double-blind randomised controlled phase I study of 2% docusate sodium vaginal gel, AIDS, Vol: 15, Pages: S59-S60, ISSN: 0269-9370
Saito M, Taylor GP, Saito A, et al., 2001, In vivo selection of T-cell receptor junctional region sequences by HLA-A2 human T-cell lymphotropic virus type 1 Tax11-29 peptide complexes, JOURNAL OF VIROLOGY, Vol: 75, Pages: 1065-1071, ISSN: 0022-538X
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- Citations: 17
Bobkova MR, Kazennova EV, Selimova LM, et al., 2001, Serological approaches to subtyping of HIV-1 in injecting drug users in Russia: evidence of subtype homogeneity at the main sites of the epidemic, INTERNATIONAL JOURNAL OF STD & AIDS, Vol: 12, Pages: 34-40, ISSN: 0956-4624
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- Citations: 4
Taylor GP, Goubau P, Coste J, et al., 2001, The HTLV European Research Network International Antenatal Seroprevalence Study (HERNIAS), AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 17, Pages: S9-S9, ISSN: 0889-2229
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- Citations: 1
Taylor GP, Gessain A, Popescu DM, et al., 2001, Demographics and survival of the first 100 patients in the HTLV European research network ATLL register, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 17, Pages: S42-S42, ISSN: 0889-2229
Hanon E, Goon P, Taylor GP, et al., 2001, High production of interferon-gamma but not interleukin-2 by human T cell lymphotropic virus type I (HTLV-I)-infected peripheral blood mononuclear cells, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 17, Pages: S27-S27, ISSN: 0889-2229
Saito M, Taylor GP, Saito A, et al., 2001, In vivo selection of TCR junctional region sequences by HLAA2/human T cell leukemia virus type-1 (HTLV-1) Tax11-19 peptide complexes., AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 17, Pages: S61-S61, ISSN: 0889-2229
Weber J, 2001, The pathogenesis of HIV-1 infection, BRITISH MEDICAL BULLETIN, Vol: 58, Pages: 61-72, ISSN: 0007-1420
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- Citations: 27
Taylor GP, Gessain A, Popescu DM, et al., 2001, Demographics and survival of the first 100 patients in the HTLV European Research Network ATLL register, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 17, Pages: S69-S69, ISSN: 0889-2229
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- Citations: 1
Clarke JR, Galpin S, Braganza R, et al., 2000, Comparative quantification of diverse serotypes of HIV-1 in plasma from a diverse population of patients, JOURNAL OF MEDICAL VIROLOGY, Vol: 62, Pages: 445-449, ISSN: 0146-6615
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- Citations: 18
Ward H, Ison CA, Day SE, et al., 2000, A prospective social and molecular investigation of gonococcal transmission, LANCET, Vol: 356, Pages: 1812-1817, ISSN: 0140-6736
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- Citations: 41
Hanon E, Asquith RE, Taylor GP, et al., 2000, High frequency of viral protein expression in human T cell lymphotropic virus type 1-infected peripheral blood mononuclear cells, AIDS RESEARCH AND HUMAN RETROVIRUSES, Vol: 16, Pages: 1711-1715, ISSN: 0889-2229
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- Citations: 34
Hanon E, Stinchcombe JC, Saito M, et al., 2000, Fratricide among CD8<SUP>+</SUP> T lymphocytes naturally infected with human T cell lymphotropic virus type I, IMMUNITY, Vol: 13, Pages: 657-664, ISSN: 1074-7613
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- Citations: 141
Stainsby CM, Lyall EGH, Taylor GP, et al., 2000, A significant number of uninfected infants can be HIV RNA (false) positive, AIDS, Vol: 14, Pages: S132-S132, ISSN: 0269-9370
White N, Israel-Biet D, Coker R, et al., 2000, Compartmentalisation of HIV-1 resistance mutations between the lung and blood, AIDS, Vol: 14, Pages: S118-S119, ISSN: 0269-9370
Galpin S, Beddows S, Johargy A, et al., 2000, HIV-1 genetic subtypes and antiretroviral therapy resistance testing, AIDS, Vol: 14, Pages: S118-S118, ISSN: 0269-9370
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