Imperial College London
Alternate

Joanne P. Webster

Faculty of Medicine, School of Public Health

Visiting Professor
 
 
 
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Contact

 

joanne.webster Website

 
 
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Location

 

Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Jones:2020:10.1038/s41598-020-57736-x,
author = {Jones, BP and Norman, BF and Borrett, HE and Attwood, SW and Mondal, MMH and Walker, AJ and Webster, JP and Jayanthe, Rajapakse PRV and Lawton, SP},
doi = {10.1038/s41598-020-57736-x},
journal = {Scientific Reports},
title = {Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale},
url = {http://dx.doi.org/10.1038/s41598-020-57736-x},
volume = {10},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Schistosoma spindale and Schistosoma indicum are ruminant-infecting trematodes of the Schistosoma indicum group that are widespread across Southeast Asia. Though neglected, these parasites can cause major pathology and mortality to livestock leading to significant welfare and socio-economic issues, predominantly amongst poor subsistence farmers and their families. Here we used mitogenomic analysis to determine the relationships between these two sympatric species of schistosome and to characterise S. spindale diversity in order to identify possible cryptic speciation. The mitochondrial genomes of S. spindale and S. indicum were assembled and genetic analyses revealed high levels of diversity within the S. indicum group. Evidence of functional changes in mitochondrial genes indicated adaptation to environmental change associated with speciation events in S. spindale around 2.5 million years ago. We discuss our results in terms of their theoretical and applied implications.
AU  - Jones,BP
AU  - Norman,BF
AU  - Borrett,HE
AU  - Attwood,SW
AU  - Mondal,MMH
AU  - Walker,AJ
AU  - Webster,JP
AU  - Jayanthe,Rajapakse PRV
AU  - Lawton,SP
DO  - 10.1038/s41598-020-57736-x
PY  - 2020///
SN  - 2045-2322
TI  - Divergence across mitochondrial genomes of sympatric members of the Schistosoma indicum group and clues into the evolution of Schistosoma spindale
T2  - Scientific Reports
UR  - http://dx.doi.org/10.1038/s41598-020-57736-x
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32051431
UR  - http://hdl.handle.net/10044/1/76992
VL  - 10
ER  -
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