Imperial College London
Alternate

Joanne P. Webster

Faculty of Medicine, School of Public Health

Visiting Professor
 
 
 
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Contact

 

joanne.webster Website

 
 
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Location

 

Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Léger:2020:10.1016/S2542-5196(20)30129-7,
author = {Léger, E and Borlase, A and Fall, CB and Diouf, ND and Diop, SD and Yasenev, L and Catalano, S and Thiam, CT and Ndiaye, A and Emery, A and Morrell, A and Rabone, M and Ndao, M and Faye, B and Rollinson, D and Rudge, JW and Sène, M and Webster, JP},
doi = {10.1016/S2542-5196(20)30129-7},
journal = {The Lancet Planetary Health},
pages = {e330--e342},
title = {Prevalence and distribution of schistosomiasis in human, livestock, and snail populations in northern Senegal: a One Health epidemiological study of a multi-host system.},
url = {http://dx.doi.org/10.1016/S2542-5196(20)30129-7},
volume = {4},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Schistosomiasis is a neglected tropical disease of global medical and veterinary importance. As efforts to eliminate schistosomiasis as a public health problem and interrupt transmission gather momentum, the potential zoonotic risk posed by livestock Schistosoma species via viable hybridisation in sub-Saharan Africa have been largely overlooked. We aimed to investigate the prevalence, distribution, and multi-host, multiparasite transmission cycle of Haematobium group schistosomiasis in Senegal, West Africa. METHODS: In this epidemiological study, we carried out systematic surveys in definitive hosts (humans, cattle, sheep, and goats) and snail intermediate hosts, in 2016-18, in two areas of Northern Senegal: Richard Toll and Lac de Guiers, where transmission is perennial; and Barkedji and Linguère, where transmission is seasonal. The occurrence and distribution of Schistosoma species and hybrids were assessed by molecular analyses of parasitological specimens obtained from the different hosts. Children in the study villages aged 5-17 years and enrolled in school were selected from school registers. Adults (aged 18-78 years) were self-selecting volunteers. Livestock from the study villages in both areas were also randomly sampled, as were post-mortem samples from local abattoirs. Additionally, five malacological surveys of snail intermediate hosts were carried out at each site in open water sources used by the communities and their animals. FINDINGS: In May to August, 2016, we surveyed 375 children and 20 adults from Richard Toll and Lac de Guiers, and 201 children and 107 adults from Barkedji and Linguère; in October, 2017, to January, 2018, we surveyed 386 children and 88 adults from Richard Toll and Lac de Guiers, and 323 children and 85 adults from Barkedji and Linguère. In Richard Toll and Lac de Guiers the prevalence of urogenital schistosomiasis in children was estimated to be 87% (95% CI 80-95) in 2016 and 88% (82-95) in 2017-
AU  - Léger,E
AU  - Borlase,A
AU  - Fall,CB
AU  - Diouf,ND
AU  - Diop,SD
AU  - Yasenev,L
AU  - Catalano,S
AU  - Thiam,CT
AU  - Ndiaye,A
AU  - Emery,A
AU  - Morrell,A
AU  - Rabone,M
AU  - Ndao,M
AU  - Faye,B
AU  - Rollinson,D
AU  - Rudge,JW
AU  - Sène,M
AU  - Webster,JP
DO  - 10.1016/S2542-5196(20)30129-7
EP  - 342
PY  - 2020///
SN  - 2542-5196
SP  - 330
TI  - Prevalence and distribution of schistosomiasis in human, livestock, and snail populations in northern Senegal: a One Health epidemiological study of a multi-host system.
T2  - The Lancet Planetary Health
UR  - http://dx.doi.org/10.1016/S2542-5196(20)30129-7
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32800151
UR  - https://www.sciencedirect.com/science/article/pii/S2542519620301297?via%3Dihub
UR  - http://hdl.handle.net/10044/1/82047
VL  - 4
ER  -
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