Imperial College London

Dr Jonathan Underwood

Faculty of MedicineDepartment of Infectious Disease

Honorary Clinical Research Fellow



+44 (0)20 3312 1466jonathan.underwood Website CV




Winston Churchill WingSt Mary's Campus





Jonathan Underwood is an infectious diseases and general medicine consultant working at the University Hospital of Wales. He completed a PhD under the supervision of Prof. Alan Winston and Dr. Robert Leech. His main research interest is understanding neurological sequelae of infections particularly the pathogenesis of cognitive impairment in treated HIV-disease and investigating the potential aetiological role of antiretroviral central nervous system toxicity. Primarily using advanced neuroimaging he collaborates with the Computational, Cognitive and Clinical Neuroimaging Laboratory (C3NL) based at Hammersmith Hospital.

Jonathan has recently been awarded an MRC-NIHR Clinical Academic Research Partnership grant to study blood-brain barrier dysfunction and cognitive outcomes following bloodstream infection. This work is in partnership with Prof Neil Harrison based at CUBRIC and the SAIL Databank at Swansea University and Public Health Wales.

Selected Publications

Journal Articles

Underwood J, Robertson KR, Winston A, 2015, Could antiretroviral neurotoxicity play a role in the pathogenesis of cognitive impairment in treated HIV disease?, AIDS, Vol:29, ISSN:0269-9370, Pages:253-261

More Publications