Imperial College London

Professor Joshua B. Edel

Faculty of Natural SciencesDepartment of Chemistry

Professor of Biosensing & Analytical Sciences
 
 
 
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Contact

 

+44 (0)20 7594 0754joshua.edel Website

 
 
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Assistant

 

Mr John Murrell +44 (0)20 7594 2845

 
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Location

 

442AChemistrySouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Crick:2017:10.1021/acsphotonics.7b00825,
author = {Crick, CR and Albella, P and Kim, H-J and Ivanov, AP and Kim, K-B and Maier, SA and Edel, JB},
doi = {10.1021/acsphotonics.7b00825},
journal = {ACS Photonics},
pages = {2835--2842},
title = {Low-Noise Plasmonic Nanopore Biosensors for Single Molecule Detection at Elevated Temperatures},
url = {http://dx.doi.org/10.1021/acsphotonics.7b00825},
volume = {4},
year = {2017}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Advanced single molecular analysis is a key stepping stone for the rapid sensing and characterization of biomolecules. This will only be made possible through the implementation of versatile platforms, with high sensitivities and the precise control of experimental conditions. The presented work details an advancement of this technology, through the development of a low-noise Pyrex/silicon nitride/gold nanopore platform. The nanopore is surrounded by a plasmonic bullseye structure and provides targeted and controllable heating via laser irradiation, which is directed toward the center of the pore. The device architecture is investigated using multiwavelength laser heating experiments and 'individual DNA molecules are detected under controlled heating. The plasmonic features, optimized through numerical simulations, are tuned to the wavelength of incident light, ensuring a platform that provides substantial heating with high signal-to-noise.
AU - Crick,CR
AU - Albella,P
AU - Kim,H-J
AU - Ivanov,AP
AU - Kim,K-B
AU - Maier,SA
AU - Edel,JB
DO - 10.1021/acsphotonics.7b00825
EP - 2842
PY - 2017///
SN - 2330-4022
SP - 2835
TI - Low-Noise Plasmonic Nanopore Biosensors for Single Molecule Detection at Elevated Temperatures
T2 - ACS Photonics
UR - http://dx.doi.org/10.1021/acsphotonics.7b00825
UR - http://hdl.handle.net/10044/1/53813
VL - 4
ER -