Justin Mason is Professor of Vascular Rheumatology within Vascular Sciences, National Heart and Lung Institute based within the Imperial College Centre for Translational and Experimental Medicine at the Hammersmith Hospital Campus.
Professor Mason leads a basic science research group investigating molecular mechanisms involved in the regulation of vascular endothelial cytoprotection. His work aims to develop a detailed understanding of innate signalling pathways to facilitate the rational design of novel therapies by which vascular endothelium can be conditioned in order to minimise vascular injury, EC dysfunction and subsequent atherogenesis in patients with systemic inflammatory disease. In addition, he is actively involved in clinical translational research, which aims to optimise clinical assessment and treatment of the large vessel vasculitides (Takayasu and Giant Cell arteritis) and understand the relationship between chronic endothelial dysfunction and accelerated atherosclerosis. Read more on Justin's research.
Justin graduated in Medicine in 1986 from the University of London and trained in Rheumatology at the Kennedy Institute of Rheumatology, Charing Cross Hospital and at the Royal Postgraduate Medical School in London. Following award of a Medical Research Council Training Fellowship in 1992 and subsequently a PhD degree in 1996 from Imperial College London, he returned to clinical medicine as senior registrar in medicine and rheumatology at Hammersmith Hospital London. He was the recipient of Arthritis Research UK Intermediate and Senior Clinical Research Fellowships in 1997 and 2000 respectively. He was appointed Professor of Vascular Rheumatology at Imperial College in 2009, Head of Vascular Sciences in 2017 and Head of the Cardiovascular Division of the National Heart and Lung Institute in 2018. He is a Fellow of the Royal College of Physicians and of the Association of Physicians of Great Britain and Ireland.
Justin is co-director of the Imperial College Centre of Excellence in Vasculitis Research. He has previously served as Chair of the Arthritis Research UK Research Education and Capacity Committee, on their Fellowship panel, the British Society for Rheumatology (BSR) Heberden Committee and the Medical Research Society Committee. He was awarded the Heberden Oration and Medal by the BSR in 2018. Justin is currently the Chair of the British Heart Foundation Project Grant Committee and serves on the BHF Medical Director’s Strategy committee.
et al., Pro-arrhythmic electrophysiological and structural remodelling in rheumatoid arthritis, Ajp-heart and Circulatory Physiology
et al., 2020, Novel Positron Emission Tomography Tracers for Imaging Vascular Inflammation, Current Cardiology Reports, Vol:22, ISSN:1523-3782
Porter A, Mason JC, 2020, Intervention in Takayasu aortitis: when, where and how?, Hearts, Vol:1, Pages:62-74
et al., 2020, Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science, Cardiovascular Research, ISSN:0008-6363
et al., 2020, Metformin directly suppresses atherosclerosis in normoglycemic mice via haematopoietic Adenosine Monophosphate-Activated Protein Kinase (AMPK), Cardiovascular Research, ISSN:0008-6363