Imperial College London
Alternate

Professor Karim Meeran

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor of Endocrinology
 
 
 
//

Contact

 

+44 (0)20 8846 1065k.meeran

 
 
//

Location

 

9E05Charing Cross HospitalCharing Cross Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Dubb:2014:10.1136/bcr-2013-200221,
author = {Dubb, SS and Tafader, A and Meeran, K and Fletcher, J},
doi = {10.1136/bcr-2013-200221},
journal = {BMJ Case Rep},
title = {Hypertension in a teenager: a family affair.},
url = {http://dx.doi.org/10.1136/bcr-2013-200221},
volume = {2014},
year = {2014}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - We present a young, lean, female patient following surveillance by the general practitioner for abnormally high blood pressure readings. Her grandmother died at a young age because of hypertension which shows her family has significant history for hypertension. Her symptoms and signs included feeling hot and nauseous following exercise, sweating and palpitations. Her young age and significant family history immediately prioritises secondary causes including phaeochromocytoma and familial syndromes causing hypertension. Urinary results showed significantly elevated norepinephrine, MRI scanning revealed a mass not within but adjacent to the right adrenal gland while CT-based scanning showed no other ectopics. The patient subsequently underwent surgical intervention at Great Ormond Street Hosptial and following a difficult procedure, that initially started laparoscopically and was converted to open, the tumour was excised. Histopathology and genetic analysis ultimately revealed the patient to have suffered from a paraganglioma type 4 syndrome with a missense mutation of the SDHB gene.
AU  - Dubb,SS
AU  - Tafader,A
AU  - Meeran,K
AU  - Fletcher,J
DO  - 10.1136/bcr-2013-200221
PY  - 2014///
TI  - Hypertension in a teenager: a family affair.
T2  - BMJ Case Rep
UR  - http://dx.doi.org/10.1136/bcr-2013-200221
UR  - https://www.ncbi.nlm.nih.gov/pubmed/24429046
VL  - 2014
ER  -
Download