I am a Senior Clinical Lecturer and Honorary Paediatric Infectious Diseases Consultant at the Centre for International Child Health at Imperial. My main research interests are age-related immune responses to infectious diseases, in particular to Group B-streptococcus(GBS) in neonates. I am interested in improving our knowledge of how maternal antibody in blood and breast milk is passed to babies and how this protects them from colonisation and disease and how we might improve this with vaccination. I am funded by the the Thrasher Foundation and the Bill and Melinda Gates Foundation.
Royal College of Paediatrics and Child Health (RCPCH), Academic Paediatrics Association (APA), British Paediatric Allergy Infection and Immunity Group (BPAIIG), Children's HIV Association (CHIVA) and International Child Health Group.
et al., SIgA, TGF-ß1, IL-10 and TNFa in colostrum are associated with infant Group B Streptococcus colonisation, Frontiers in Immunology, ISSN:1664-3224
et al., 2017, Immunogenicity and safety of 13-valent pneumococcal conjugate vaccine (PCV13) formulated with 2-phenoxyethanol in multidose vials given with routine vaccination in healthy infants: An open-label randomized controlled trial, Vaccine, Vol:35, ISSN:0264-410X, Pages:3256-3263
et al., 2017, Association between functional antibody against Group B Streptococcus and maternal and infant colonization in a Gambian cohort, Vaccine, Vol:35, ISSN:0264-410X, Pages:2970-2978
et al., 2016, Role of human milk oligosaccharides in Group B Streptococcus colonisation, Clinical & Translational Immunology, Vol:5, ISSN:2050-0068
et al., 2016, Lack of evidence for the efficacy of enhanced surveillance compared to other specific interventions to control neonatal healthcare-associated infection outbreaks, Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol:110, ISSN:0035-9203, Pages:98-106