18 results found
O'Reilly KM, Verity R, Durry E, et al., 2018, Population sensitivity of acute flaccid paralysis and environmental surveillance for serotype 1 poliovirus in Pakistan: an observational study, BMC INFECTIOUS DISEASES, Vol: 18, ISSN: 1471-2334
Imran H, Raja D, Grassly NC, et al., 2018, Routine immunization in Pakistan: comparison of multiple data sources and identification of factors associated with vaccination, INTERNATIONAL HEALTH, Vol: 10, Pages: 84-91, ISSN: 1876-3413
Molodecky NA, Blake IM, O'Reilly KM, et al., 2017, Risk factors and short-term projections for serotype-1 poliomyelitis incidence in Pakistan: A spatiotemporal analysis, PLOS MEDICINE, Vol: 14, ISSN: 1549-1676
O'Reilly KM, Lamoureux C, Molodecky NA, et al., 2017, An assessment of the geographical risks of wild and vaccine-derived poliomyelitis outbreaks in Africa and Asia, BMC INFECTIOUS DISEASES, Vol: 17, ISSN: 1471-2334
Pons-Salort M, Molodecky NA, O'Reilly KM, et al., 2016, Population Immunity against Serotype-2 Poliomyelitis Leading up to the Global Withdrawal of the Oral Poliovirus Vaccine: Spatio-temporal Modelling of Surveillance Data, PLOS MEDICINE, Vol: 13, ISSN: 1549-1676
O'Reilly KM, Cori A, Durry E, et al., 2015, A New Method for Estimating the Coverage of Mass Vaccination Campaigns Against Poliomyelitis From Surveillance Data, AMERICAN JOURNAL OF EPIDEMIOLOGY, Vol: 182, Pages: 961-970, ISSN: 0002-9262
Parker EPK, Molodecky NA, Pons-Salort M, et al., 2015, Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame, EXPERT REVIEW OF VACCINES, Vol: 14, Pages: 1113-1123, ISSN: 1476-0584
De Maio N, Wu C-H, O'Reilly KM, et al., 2015, New Routes to Phylogeography: A Bayesian Structured Coalescent Approximation, PLOS GENETICS, Vol: 11, ISSN: 1553-7404
Metcalf CJE, Tatem A, Bjornstad ON, et al., 2014, Transport networks and inequities in vaccination: remoteness shapes measles vaccine coverage and prospects for elimination across Africa, Epidemiology and Infection, Vol: 143, Pages: 1457-1466, ISSN: 1469-4409
Measles vaccination is estimated to have averted 13·8 million deaths between 2000 and 2012.Persisting heterogeneity in coverage is a major contributor to continued measles mortality, and abarrier to measles elimination and introduction of rubella-containing vaccine. Our objective is toidentify determinants of inequities in coverage, and how vaccine delivery must change to achieveelimination goals, which is a focus of the WHO Decade of Vaccines. We combined estimates oftravel time to the nearest urban centre (550 000 people) with vaccination data from DemographicHealth Surveys to assess how remoteness affects coverage in 26 African countries. Building on astatistical mapping of coverage against age and geographical isolation, we quantified howmodifying the rate and age range of vaccine delivery affects national coverage. Our scenarioanalysis considers increasing the rate of delivery of routine vaccination, increasing the target agerange of routine vaccination, and enhanced delivery to remote areas. Geographical isolation plays akey role in defining vaccine inequity, with greater inequity in countries with lower measles vaccinecoverage. Eliminating geographical inequities alone will not achieve thresholds for herd immunity,indicating that changes in delivery rate or age range of routine vaccination will be required. Measlesvaccine coverage remains far below targets for herd immunity in many countries on the Africancontinent and is likely to be inadequate for achieving rubella elimination. The impact of strategiessuch as increasing the upper age range eligible for routine vaccination should be considered.
O'Reilly KM, 2012, Polio vaccination in Pakistan Reply, LANCET, Vol: 380, Pages: 1645-1646, ISSN: 0140-6736
O'Reilly KM, Durry E, ul Islam O, et al., 2012, The effect of mass immunisation campaigns and new oral poliovirus vaccines on the incidence of poliomyelitis in Pakistan and Afghanistan, 2001-11: a retrospective analysis, LANCET, Vol: 380, Pages: 491-498, ISSN: 0140-6736
O'Reilly KM, Chauvin C, Aylward RB, et al., 2011, A Statistical Model of the International Spread of Wild Poliovirus in Africa Used to Predict and Prevent Outbreaks, PLOS MEDICINE, Vol: 8, ISSN: 1549-1676
O'Reilly KM, Low JC, Denwood MJ, et al., 2010, Associations between the Presence of Virulence Determinants and the Epidemiology and Ecology of Zoonotic Escherichia coli, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Vol: 76, Pages: 8110-8116, ISSN: 0099-2240
O'Reilly KM, Medley GF, Green LE, 2010, The control of Corynebacterium pseudotuberculosis infection in sheep flocks: A mathematical model of the impact of vaccination, serological testing, clinical examination and lancing of abscesses, PREVENTIVE VETERINARY MEDICINE, Vol: 95, Pages: 115-126, ISSN: 0167-5877
O'Reilly KM, Green LE, Malone FE, et al., 2008, Parameter estimation and simulations of a mathematical model of Corynebacterium pseudotuberculosis transmission in sheep, PREVENTIVE VETERINARY MEDICINE, Vol: 83, Pages: 242-259, ISSN: 0167-5877
O'Reilly KM, Harris MJ, Mendl M, et al., 2006, Factors associated with preweaning mortality on commercial pig farms in England and Wales, VETERINARY RECORD, Vol: 159, Pages: 193-196, ISSN: 0042-4900
O'Reilly KM, Green MJ, Peeler EJ, et al., 2006, Investigation of risk factors for clinical mastitis in British dairy herds with bulk milk somatic cell counts less than 150,000 cells/ml, VETERINARY RECORD, Vol: 158, Pages: 649-653, ISSN: 0042-4900
Malone FE, Fee SA, Kamp EM, et al., 2006, A serological investigation of caseous lymphadenitis in four flocks of sheep, Irish Veterinary Journal, Vol: 59, Pages: 19-21, ISSN: 1393-3817
A double antibody sandwich ELISA developed by ID-DLO, Lelystad to detect Corynebacterium pseudotuberculosis infection was used on 329 sheep from four pedigree Suffolk flocks in which clinical cases of caseous lymphadenitis (CLA) had occurred. At subsequent necropsy, typical CLA lesions were seen in 133 sheep, and the diagnosis was confirmed on culture. Lesions were most commonly seen in lungs (n = 46), parotid lymph nodes (n = 44), prescapular lymph nodes (n = 38) and mediastinal lymph nodes (n = 31). The sensitivity of the ELISA test for detecting culture-positive sheep was 0.88, while the specificity of the test was 0.55. The antibody ELISA detected 87.5 per cent of sheep that had CLA lesions restricted to internal organs only. It was concluded that the ELISA test has a valuable role in detecting sheep with both clinical and subclinical CLA.
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